5.4.3.8: glutamate-1-semialdehyde 2,1-aminomutase

This is an abbreviated version!
For detailed information about glutamate-1-semialdehyde 2,1-aminomutase, go to the full flat file.

Word Map on EC 5.4.3.8

5.4.3.8

chlorophyll

5-aminolevulinic

tetrapyrrole

glutamyl-trna

delta-aminolevulinic

synechococcus

gabaculine

hema

4,5-diaminovalerate

trnaglu

4,5-dioxovalerate

aldimine

glutr

five-carbon

glutamyl-trnaglu

trna-dependent

3-amino-2,3-dihydrobenzoic

chelatase

mg-chelatase

Reaction

Synonyms

Aminotransferase, glutamate semialdehyde, AtGSA1, EC 2.7.2.13, Glutamate 1-semialdehyde aminotransferase, glutamate-1-semialdehyde amino-transferase, glutamate-1-semialdehyde aminomutase, Glutamate-1-semialdehyde aminotransferase, glutamate-1-semialdehyde-2,1-aminomutase, glutamate-1-semialdehyde-aminomutase, GSA, GSA aminotransferase, GSA-AT, GSA1, GSAM, GSAT, HemL, PA4088, protein PA4088

ECTree

5 Isomerases

5.4 Intramolecular transferases

5.4.3 Transferring amino groups

5.4.3.8 glutamate-1-semialdehyde 2,1-aminomutase

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Results	in table
3	Activating Compound
32180	AA Sequence
1	CAS Registry Number
17	Cloned(Commentary)
25	Cofactor
8	Crystallization (Commentary)
2	Expression
8	General Information
2	IC50 Value
23	Inhibitors
8	KM Value [mM]
5	Localization
2	Metals/Ions
17	Molecular Weight [Da]
25	Natural Substrates/ Products (Substrates)
74	Organism
7	Pathway
50	PDB ID
3	pH Optimum
2	pH Range
8	Protein Variants
16	Purification (Commentary)
8	Reaction
2	Reaction Type
47	Reference
7	Source Tissue
8	Specific Activity [micromol/min/mg]
68	Substrates and Products (Substrate)
19	Subunits
39	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Turnover Number [1/s]

Cloned

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Cloned on EC 5.4.3.8 - glutamate-1-semialdehyde 2,1-aminomutase

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expressed in Escherichia coli

Synechococcus sp.

P24630

703619

expressed in Escherichia coli BL21(DE3) cells

Bacillus subtilis

P30949

714041

expressed in Escherichia coli DEX cells

Escherichia coli

716103

expression in Escherichia coli

7 entries

gene AtGSA1, recombinant expression of His6-tagged enzyme lacking the N-terminal plastid-targeting sequences in Escherichia coli strain BL21(DE3)

Arabidopsis thaliana

P42799

746660

gene hemL from Corynebacterium glutamicum, recombinant co-expression with gene hemA, encoding the glutamyl t-RNA reductase, from Salmonella typhimurium strain LT2, in Corynebacterium glutamicum strain ATCC 13032 in an operon under the control of trc promoter, and transcription is terminated with the rrnBT1T2 terminator, subcloning of hemL in Escherichia coli strain BL21(DE3)

Corynebacterium glutamicum

Q8NT73

747678

gene pa4088, recombinant expression of His-tagged wild-type and mutant enzymes in Escherichia coli strain BL21(DE3)

Pseudomonas aeruginosa

Q9HWU0

747005

mutant enzyme Lys265Arg, overexpression

Escherichia coli

3432

wild-type enzyme and gabaculine-resistant mutant enzyme, overexpression in Escherichia coli

Synechococcus sp.

3430