5.4.3.6: tyrosine 2,3-aminomutase

This is an abbreviated version!
For detailed information about tyrosine 2,3-aminomutase, go to the full flat file.

Reaction

Synonyms

3,5-dihydro-5-methylidene-4H-imidazol-4-one-dependent aminomutase, 3,5-dihydro-5-methylidine-4H-imidazol-4-one-dependent tyrosine aminomutase, Aminomutase, tyrosine 2,3-, CmdF, MfTAM, MIO-dependent aminomutase, MIO-dependent tyrosine aminomutase, More, MxTAM, OsTAM, SgcC4, TAM, Tam1, Tyrosine alpha,beta-amino mutase, Tyrosine alpha,beta-mutase, tyrosine aminomutase

ECTree

     5 Isomerases

         5.4 Intramolecular transferases

             5.4.3 Transferring amino groups

                5.4.3.6 tyrosine 2,3-aminomutase

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Results	in table
152	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
4	Cofactor
2	Crystallization (Commentary)
2	Expression
9	General Information
1	General Stability
6	IC50 Value
18	Inhibitors
10	kcat/KM [mM/s]
16	KM Value [mM]
2	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
16	Organism
4	Pathway
8	PDB ID
7	pH Optimum
2	pH Range
43	Protein Variants
8	Purification (Commentary)
5	Reaction
5	Reaction Type
16	Reference
5	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
35	Substrates and Products (Substrate)
2	Subunits
35	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]
18	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 5.4.3.6 - tyrosine 2,3-aminomutase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

(2S,3R)-3-(4-fluorophenyl)oxirane-2-carboxylate

Streptomyces globisporus

-

-

691277

(2S,3R)-3-(4-methoxyphenyl)oxirane-2-carboxylate

Streptomyces globisporus

-

-

691277

(2S,3R)-3-phenyloxirane-2-carboxylate

Streptomyces globisporus

-

-

691277

(3R)-3-ammonio-2,2-difluoro-3-(4-hydroxyphenyl)propanoate

Streptomyces globisporus

-

-

691277

(3R)-3-ammonio-2,2-difluoro-3-(4-methoxyphenyl)propanoate

Streptomyces globisporus

-

-

691277

(3R)-3-ammonio-2,2-difluoro-3-phenylpropanoate

Streptomyces globisporus

-

-

691277

2-oxoglutarate

Brevibacillus brevis

-

-

3405

Cd2+

Streptomyces globisporus

-

weak inhibition

650190

Cu2+

Streptomyces globisporus

-

strong inhibition

650190

NaBH4

Brevibacillus brevis

-

-

3405

p-hydroxycinnamate

Brevibacillus brevis

-

-

3405

p-hydroxyphenylpyruvate

Brevibacillus brevis

-

-

3405

phenylhydrazine

Brevibacillus brevis

-

-

3405

phenylpyruvate

Brevibacillus brevis

-

-

3405

pyruvate

Brevibacillus brevis

-

-

3405

Semicarbazide

Brevibacillus brevis

-

-

3405

Zn2+

Streptomyces globisporus

-

weak inhibition

650190

additional information

Oryza sativa Japonica Group

-

hemipteran and lepidopteran herbivores show no negative effects at physiologically relevant beta-tyrosine concentrations

748914

-