5.4.2.7: phosphopentomutase
This is an abbreviated version!
For detailed information about phosphopentomutase, go to the full flat file.
Word Map on EC 5.4.2.7
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5.4.2.7
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nucleoside
-
purine
-
5-phosphate
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phosphoglucomutase
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deoxyriboaldolase
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2-deoxyribose
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ribose-5-phosphate
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nucleobase
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phosphorylases
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deoxyribonucleosides
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2'-deoxyribonucleoside
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ribokinase
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1,6-diphosphate
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phosphorolysis
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phosphomutases
-
analysis
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biotechnology
- 5.4.2.7
- nucleoside
- purine
- 5-phosphate
- phosphoglucomutase
- deoxyriboaldolase
- 2-deoxyribose
- ribose-5-phosphate
-
nucleobase
- phosphorylases
- deoxyribonucleosides
- 2'-deoxyribonucleoside
- ribokinase
- 1,6-diphosphate
-
phosphorolysis
-
phosphomutases
- analysis
- biotechnology
Reaction
Synonyms
alpha-D-Glucose-1,6-bisphosphate:deoxy-D-ribose-1-phosphate phosphotransferase, alpha-D-ribose1,5-phosphomutase, deoB, Deoxyribomutase, Deoxyribose phosphomutase, EC 2.7.5.6, PGM3, Phosphodeoxyribomutase, Phosphomutase, deoxyribose, phosphopentomutase, Phosphoribomutase, PPM, PPMase
ECTree
5.4.2.7 phosphopentomutaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 5.4.2.7 - phosphopentomutase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-deoxy-D-ribose 1-phosphate
2-deoxy-D-ribose 5-phosphate
-
-
-
?
Glucose 1-phosphate
?
-
at 2.4% of the activity relative to ribose 1-phosphate
-
-
?
Ribose 1-phosphate
?
-
inducible enzyme. In order to enter the pentose phosphate cycle ribose 1-phosphate must be isomerized to ribose 5-phosphate
-
-
?
2,3-dideoxyribose 5-phosphate
2,3-dideoxyribose 1-phosphate
-
-
-
?, r
2,3-dideoxyribose 5-phosphate
2,3-dideoxyribose 1-phosphate
-
-
-
?
2-deoxy-D-ribose 5-phosphate
2-deoxy-D-ribose 1-phosphate
-
-
-
r
2-deoxyribose 5-phosphate
2-deoxyribose 1-phosphate
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at 156% of the activity relative to ribose 5-phosphate
-
?
2-deoxyribose 5-phosphate
2-deoxyribose 1-phosphate
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at 156% of the activity relative to ribose 5-phosphate
-
?
alpha-D-ribose 1-phosphate
D-ribose 5-phosphate
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PPM is involve in the salvage pathway of nucleoside synthesis
-
?
alpha-D-ribose 1-phosphate
D-ribose 5-phosphate
-
-
-
?
D-Arabinose 5-phosphate
D-Arabinose 1-phosphate
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at 8.61% of the activity relative to ribose 5-phosphate
-
-
?
D-Arabinose 5-phosphate
D-Arabinose 1-phosphate
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at 8.61% of the activity relative to ribose 5-phosphate
-
-
?
D-ribose 1-phosphate
D-ribose 5-phosphate
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only the reverse reaction is mentioned: D-ribose 5-phosphate to D-ribose 1-phosphate
-
-
?
D-ribose 1-phosphate
D-ribose 5-phosphate
-
only the reverse reaction is mentioned: D-ribose 5-phosphate to D-ribose 1-phosphate
-
?
D-ribose 1-phosphate
D-ribose 5-phosphate
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only the reverse reaction is mentioned: D-ribose 5-phosphate to D-ribose 1-phosphate
-
?
D-ribose 1-phosphate
D-ribose 5-phosphate
-
-
-
?
Deoxyribose 1-phosphate
Deoxyribose 5-phosphate
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at 25% of the activity relative to ribose 1-phosphate
-
-
?
additional information
?
-
-
does not accept 2,3-dideoxyribose 5-phosphate as substrate
-
-
?
additional information
?
-
-
the enzyme is involved in the salvage pathway of nucleoside synthesis
-
-
?
additional information
?
-
-
the enzyme is involved in the salvage pathway of nucleoside synthesis
-
-
?
additional information
?
-
-
Pgm3 functions as the major phosphoribomutase in vivo
-
-
?
additional information
?
-
-
phosphoglucomutases Pgm1, Pgm2, and Pgm3, EC 5.4.2.2, of Saccharomyces cerevisiae show ability to interconvert ribose-1-phosphate and ribose-5-phosphate. The purified proteins, studied in vitro with regard to their kinetic properties on glucose-1-phosphate and ribose-1-phosphate, are all active on both substrates with Pgm1 exhibiting only residual activity on ribose-1-phosphate. The Pgm2 and Pgm3 proteins have almost equal kinetic properties on ribose-1-phosphate, but Pgm2 has a 2000times higher preference for glucose-1-phosphate when compared to Pgm3
-
-
?
additional information
?
-
trace levels of activity with glucose 1-phosphate and mannose 1-phosphate. No activity with fructose 1-phosphate, N-acetylglucosamine 1-phosphate and 3-phosphoglycerate
-
-
?
additional information
?
-
-
trace levels of activity with glucose 1-phosphate and mannose 1-phosphate. No activity with fructose 1-phosphate, N-acetylglucosamine 1-phosphate and 3-phosphoglycerate
-
-
?
