5.4.2.3: phosphoacetylglucosamine mutase

This is an abbreviated version!
For detailed information about phosphoacetylglucosamine mutase, go to the full flat file.

Reaction

Synonyms

2-Acetamido-2-deoxy-D-glucose-1,6-bisphosphate:2-acetamido-2-deoxy-D-glucose 1-phosphate phosphotransferase, Acetylaminodeoxyglucose phosphomutase, Acetylglucosamine phosphomutase, AGM, AGM1, AGM1/PGM3, CaAGM1, DNA-damage-repair/toleration protein DRT101, EC 2.7.5.2, EC 2.7.5.2., HsAGM1, N-acetylglucosamine-phosphate mutase, PAGM, PGlcNAc mutase, PGM3, Phospho-N-acetylglucosamine mutase, phosphoacetylglucosamine mutase 1, Phosphomutase, acetylglucosamine

ECTree

     5 Isomerases

         5.4 Intramolecular transferases

             5.4.2 Phosphotransferases (phosphomutases)

                5.4.2.3 phosphoacetylglucosamine mutase

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Results	in table
12	Activating Compound
3255	AA Sequence
1	Application
1	CAS Registry Number
7	Cloned(Commentary)
2	Crystallization (Commentary)
7	General Information
1	General Stability
2	IC50 Value
19	Inhibitors
2	kcat/KM [mM/s]
11	KM Value [mM]
5	Localization
6	Metals/Ions
4	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
22	Organism
5	Pathway
12	PDB ID
9	pH Optimum
2	pH Range
25	Protein Variants
9	Purification (Commentary)
3	Reaction
2	Reaction Type
22	Reference
27	Source Tissue
2	Specific Activity [micromol/min/mg]
4	Storage Stability
38	Substrates and Products (Substrate)
2	Subunits
22	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]
3	Turnover Number [1/s]

Substrates Products

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of the Enzyme Summary Page.

Substrates Products on EC 5.4.2.3 - phosphoacetylglucosamine mutase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

alpha-D-glucose 1-phosphate

alpha-D-glucose 6-phosphate

Arabidopsis thaliana

-

-

748838

-

-

r

alpha-D-glucose 6-phosphate

alpha-D-glucose 1-phosphate

Arabidopsis thaliana

-

-

748838

-

-

r

D-glucose-1-phosphate

D-glucose-6-phosphate

Aedes aegypti

Q58I85

-

661887

-

-

?

glucosamine 1-phosphate

glucosamine 6-phosphate

Arabidopsis thaliana

-

-

748838

-

-

r

glucosamine 6-phosphate

glucosamine 1-phosphate

Arabidopsis thaliana

-

-

748838

-

-

r

Glucose 1-phosphate

Glucose 6-phosphate

3 entries

N-acetyl-alpha-D-glucosamine

?

Homo sapiens

O95394

-

650329

-

-

?

N-acetyl-alpha-D-glucosamine 1-phosphate

N-acetyl-alpha-D-glucosamine 6-phosphate

2 entries

N-acetyl-alpha-D-glucosamine 1-phosphate

N-acetyl-D-glucosamine 6-phosphate

6 entries

N-acetyl-alpha-D-glucosamine 6-phosphate

N-acetyl-alpha-D-glucosamine 1-phosphate

Arabidopsis thaliana

-

-

748838

-

-

r

N-Acetyl-D-glucosamine 1-phosphate

N-Acetyl-D-glucosamine 6-phosphate

4 entries

N-acetyl-D-glucosamine 6-phosphate

N-acetyl-alpha-D-glucosamine 1-phosphate

3 entries

N-Acetylglucosamine 6-phosphate

?

4 entries

N-Acetylglucosamine 6-phosphate

N-Acetylglucosamine 1-phosphate

3 entries

N-acetylglucosamine-1-phosphate

N-acetylglucosamine-6-phosphate

Aedes aegypti

Q58I85

-

661887

-

-

?

additional information

?

-

4 entries

Glucose 1-phosphate

Glucose 6-phosphate

Sus scrofa

-

-

3300

-

3300

?

Glucose 1-phosphate

Glucose 6-phosphate

Sus scrofa

-

-

3302

-

3302

?

Glucose 1-phosphate

Glucose 6-phosphate

Sus scrofa

-

in presence of glucose 1,6-diphosphate

3296

-

3296

?

N-acetyl-alpha-D-glucosamine 1-phosphate

N-acetyl-alpha-D-glucosamine 6-phosphate

Arabidopsis thaliana

-

-

748838

-

-

r

N-acetyl-alpha-D-glucosamine 1-phosphate

N-acetyl-alpha-D-glucosamine 6-phosphate

Candida albicans

Q9P4V2

-

747706

-

-

r

N-acetyl-alpha-D-glucosamine 1-phosphate

N-acetyl-D-glucosamine 6-phosphate

Candida albicans

Q9P4V2

-

650329

-

650329

?

N-acetyl-alpha-D-glucosamine 1-phosphate

N-acetyl-D-glucosamine 6-phosphate

Giardia intestinalis

-

-

2419

-

-

?

N-acetyl-alpha-D-glucosamine 1-phosphate

N-acetyl-D-glucosamine 6-phosphate

Giardia intestinalis MR4

-

-

2419

-

-

?

N-acetyl-alpha-D-glucosamine 1-phosphate

N-acetyl-D-glucosamine 6-phosphate

Homo sapiens

O95394

-

650329

-

650329

?

N-acetyl-alpha-D-glucosamine 1-phosphate

N-acetyl-D-glucosamine 6-phosphate

Trypanosoma brucei

F4NCC3

-

728329

-

-

r

N-acetyl-alpha-D-glucosamine 1-phosphate

N-acetyl-D-glucosamine 6-phosphate

Trypanosoma brucei 427

F4NCC3

-

728329

-

-

r

N-Acetyl-D-glucosamine 1-phosphate

N-Acetyl-D-glucosamine 6-phosphate

Neurospora crassa

-

-

3297

-

-

?

N-Acetyl-D-glucosamine 1-phosphate

N-Acetyl-D-glucosamine 6-phosphate

Neurospora crassa

-

specific for the alpha-1-phosphate anomer

3301

-

-

?

N-Acetyl-D-glucosamine 1-phosphate

N-Acetyl-D-glucosamine 6-phosphate

Sus scrofa

-

-

3300, 3302, 3303

-

-

?

N-Acetyl-D-glucosamine 1-phosphate

N-Acetyl-D-glucosamine 6-phosphate

Sus scrofa

-

in presence of N-acetylglucosamine 1,6-diphosphate

3296

-

3296

?

N-acetyl-D-glucosamine 6-phosphate

N-acetyl-alpha-D-glucosamine 1-phosphate

Drosophila melanogaster

Q9VTZ4

-

728799

-

-

r

N-acetyl-D-glucosamine 6-phosphate

N-acetyl-alpha-D-glucosamine 1-phosphate

Trypanosoma brucei

F4NCC3

-

728329

-

-

r

N-acetyl-D-glucosamine 6-phosphate

N-acetyl-alpha-D-glucosamine 1-phosphate

Trypanosoma brucei 427

F4NCC3

-

728329

-

-

r

N-Acetylglucosamine 6-phosphate

?

Bos taurus

-

the reaction is involved in the synthesis of active glycosyl intermediates in reticulo-endothelial tissues

3299

-

-

?

N-Acetylglucosamine 6-phosphate

?

Coffea sp.

-

enzyme in the pathway of UDP-N-acetyl-D-glucosamine formation

3305

-

-

?

N-Acetylglucosamine 6-phosphate

?

Giardia intestinalis

-

enzyme is involved in galactosamine synthesis from glucose during encystment, induced during encystment

2419

-

-

?

N-Acetylglucosamine 6-phosphate

?

Giardia intestinalis MR4

-

enzyme is involved in galactosamine synthesis from glucose during encystment, induced during encystment

2419

-

-

?

N-Acetylglucosamine 6-phosphate

N-Acetylglucosamine 1-phosphate

Blastocladiella emersonii

-

-

3298

-

3298

?

N-Acetylglucosamine 6-phosphate

N-Acetylglucosamine 1-phosphate

Bos taurus

-

-

3299

-

3299

?

N-Acetylglucosamine 6-phosphate

N-Acetylglucosamine 1-phosphate

Coffea sp.

-

-

3305

-

3305

?

additional information

?

-

Blastocladiella emersonii

-

one of the two last pathway-specific enzymes of hexosamine biosynthesis. The hexosamine pathway is regulated at the post-translational level during zoospore germination

3298

-

-

?

additional information

?

-

Trypanosoma brucei

F4NCC3

the enzyme exhibits the function of phosphoglucomutase, EC 5.4.2.2, whose gene is lost in Trypanosoma brucei, together with phosphomannomutase, EC 5.4.2.8, producing D-glucose 1-phosphate from D-glucose 6-phosphate, kinetics, overview

728329

-

-

?

additional information

?

-

Trypanosoma brucei

-

the enzyme exhibits the function of phosphoglucomutase, EC 5.4.2.2, whose gene is lost in Trypanosoma brucei, together with phosphomannomutase, EC 5.4.2.8, producing D-glucose 1-phosphate from D-glucose 6-phosphate, kinetics, overview

728329

-

-

?

additional information

?

-

Trypanosoma brucei 427

F4NCC3

the enzyme exhibits the function of phosphoglucomutase, EC 5.4.2.2, whose gene is lost in Trypanosoma brucei, together with phosphomannomutase, EC 5.4.2.8, producing D-glucose 1-phosphate from D-glucose 6-phosphate, kinetics, overview

728329

-

-

?