5.4.2.2: phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
This is an abbreviated version!
For detailed information about phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent), go to the full flat file.
Word Map on EC 5.4.2.2
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5.4.2.2
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starch
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hexokinase
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glycogen
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malate
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phosphorylase
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6-phosphogluconate
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pyrophosphorylase
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1-phosphate
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adenylate
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esterase
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erythrocyte
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galactose
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glucose-1-phosphate
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aldolase
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phosphofructokinase
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transferrin
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gpi
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allozyme
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haptoglobin
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malic
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glucosephosphate
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zymodemes
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histolytica
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hardy-weinberg
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entamoeba
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glyoxalase
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adp-glucose
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phosphoglucoisomerase
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glucose-6-phosphatase
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monomorphic
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plastidial
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glycogenolysis
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fructokinase
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diptera
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galactose-1-phosphate
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phosphohexose
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starch-gel
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uridylyltransferase
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5.3.1.9
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glc-6-p
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bloodstain
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udp-galactose
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leloir
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amyloplasts
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duffy
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udp-glc
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phosphoenzyme
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isoenzymatic
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2.7.1.1
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1,6-diphosphate
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drug development
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molecular biology
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food industry
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medicine
- 5.4.2.2
- starch
- hexokinase
- glycogen
- malate
- phosphorylase
- 6-phosphogluconate
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pyrophosphorylase
- 1-phosphate
- adenylate
- esterase
- erythrocyte
- galactose
- glucose-1-phosphate
- aldolase
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phosphofructokinase
- transferrin
- gpi
-
allozyme
- haptoglobin
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malic
-
glucosephosphate
-
zymodemes
- histolytica
-
hardy-weinberg
- entamoeba
- glyoxalase
- adp-glucose
- phosphoglucoisomerase
- glucose-6-phosphatase
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monomorphic
- plastidial
-
glycogenolysis
- fructokinase
- diptera
- galactose-1-phosphate
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phosphohexose
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starch-gel
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uridylyltransferase
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5.3.1.9
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glc-6-p
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bloodstain
- udp-galactose
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leloir
- amyloplasts
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duffy
- udp-glc
- phosphoenzyme
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isoenzymatic
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2.7.1.1
- 1,6-diphosphate
- drug development
- molecular biology
- food industry
- medicine
Reaction
Synonyms
alpha phosphoglucomutase, alpha-Pgm, alpha-phosphoglucomutase, alpha-phosphoglucomutase 1, alpha-phosphoglucose mutase, cPGM, cytosolic phosphoglucomutase, EC 2.7.5.1, Glucose phosphomutase, PGM, PGM-I, PGM-II, PGM/PMM, PGM1, PGM2, PGM3, PgmA, PgmG, phospho-glucomutase, phosphoglucomutase, phosphoglucomutase 1, phosphoglucomutase/phosphomannomutase, phosphoglucomutase1, Phosphoglucose mutase, Phosphohexomutase, phosphomannomutase/phosphoglucomutase, Phosphomutase, glucose, plastidic phosphoglucomutase, PMM/PGM, pPGM, SP-1, SpgM, SSO0207, XanA, YMR278w protein
ECTree
5.4.2.2 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)Advanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 5.4.2.2 - phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
alpha-D-glucose 1-phosphate
?
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key enzyme in carbohydrate metabolism
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?
alpha-D-glucose 1-phosphate
?
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degradation of lactose in lactic acid bacteria
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?
alpha-D-glucose 1-phosphate
alpha-D-glucose 6-phosphate
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-
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r
alpha-D-glucose 1-phosphate
alpha-D-glucose 6-phosphate
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-
-
r
alpha-D-glucose 1-phosphate
alpha-D-glucose 6-phosphate
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-
r
alpha-D-glucose 1-phosphate
D-glucose 6-phosphate
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-
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r
alpha-D-glucose 1-phosphate
D-glucose 6-phosphate
it is unclear whether either glucose or mannose phosphate represents the cellular substrate for SsoPHM. The Km values for rSsoPHM toward glucose 6-phosphate and mannose 6-phosphate are in the low millimolar range, significantly higher than that expected for a physiological substrate. Since the protein encoded by sso0207 is the only identifiable phosphohexomutase in the Sulfolbus solfataricus P2 genome, SsoPHM provides the only recognizable avenue for interconverting glucose 6-phosphate and glucose 1-phosphate during glycogen synthesis and breakdown
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-
r
alpha-D-glucose 1-phosphate
D-glucose 6-phosphate
it is unclear whether either glucose or mannose phosphate represents the cellular substrate for SsoPHM. The Km values for rSsoPHM toward glucose 6-phosphate and mannose 6-phosphate are in the low millimolar range, significantly higher than that expected for a physiological substrate. Since the protein encoded by sso0207 is the only identifiable phosphohexomutase in the Sulfolbus solfataricus P2 genome, SsoPHM provides the only recognizable avenue for interconverting glucose 6-phosphate and glucose 1-phosphate during glycogen synthesis and breakdown
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-
r
alpha-D-glucose 1-phosphate
D-glucose 6-phosphate
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-
-
?
alpha-D-glucose 1-phosphate
D-glucose 6-phosphate
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-
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?
D-glucose 6-phosphate
alpha-D-glucose 1-phosphate
it is unclear whether either glucose or mannose phosphate represents the cellular substrate for SsoPHM. The Km values for rSsoPHM toward glucose 6-phosphate and mannose 6-phosphate are in the low millimolar range, significantly higher than that expected for a physiological substrate. Since the protein encoded by sso0207 is the only identifiable phosphohexomutase in the Sulfolbus solfataricus P2 genome, SsoPHM provides the only recognizable avenue for interconverting glucose 6-phosphate and glucose 1-phosphate during glycogen synthesis and breakdown
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-
r
D-glucose 6-phosphate
alpha-D-glucose 1-phosphate
it is unclear whether either glucose or mannose phosphate represents the cellular substrate for SsoPHM. The Km values for rSsoPHM toward glucose 6-phosphate and mannose 6-phosphate are in the low millimolar range, significantly higher than that expected for a physiological substrate. Since the protein encoded by sso0207 is the only identifiable phosphohexomutase in the Sulfolbus solfataricus P2 genome, SsoPHM provides the only recognizable avenue for interconverting glucose 6-phosphate and glucose 1-phosphate during glycogen synthesis and breakdown
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-
r
Glucose 6-phosphate
?
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synthesis of glucose 1-phosphate for the formation of UDPglucose
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-
?
additional information
?
-
-
bifunctional enzyme with phosphoglucomutase and phosphomannomutase, EC 5.4.2.8, activities
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-
?
additional information
?
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bifunctional enzyme with phosphoglucomutase and phosphomannomutase, EC 5.4.2.8, activities. Strongly conserved residue His329 in the active site is critical for enzyme activity. His329 is appropriately positioned to abstract a proton from the O1/O6 hydroxyl of the phosphosugar substrates, and thus may serve as the general base in the reaction
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?
additional information
?
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Pgm3 functions as the major phosphoribomutase in vivo
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?
additional information
?
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bifunctional enzyme with phosphoglucomutase and phosphomannomutase, EC 5.4.2.8, activities, the catalytic efficiency is about 15fold higher for glucose 1-phosphate than for mannose 1-phosphate
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-
?
additional information
?
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bifunctional enzyme with phosphoglucomutase and phosphomannomutase, EC 5.4.2.8, activities, the catalytic efficiency is about 15fold higher for glucose 1-phosphate than for mannose 1-phosphate
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-
?
additional information
?
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bifunctional enzyme with phosphoglucomutase and phosphomannomutase, EC 5.4.2.8, activities, the catalytic efficiency is about 15fold higher for glucose 1-phosphate than for mannose 1-phosphate
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-
?
