5.3.99.3: prostaglandin-E synthase

This is an abbreviated version!
For detailed information about prostaglandin-E synthase, go to the full flat file.

Word Map on EC 5.3.99.3

5.3.99.3

cox-2

cyclooxygenase

arachidonic

synthases

prostanoids

lipopolysaccharide

tnf

lps

phospholipase

eicosanoids

lps-induced

pain

endometrium

leukotriene

prostacyclin

thromboxane

nsaids

indomethacin

pgf2alpha

5-lipoxygenase

il-1beta

celecoxib

nonsteroidal

interleukin-1beta

luteolysis

luteal

platinum

15-pgdh

estrous

postictal

medicine

rhodium

pencil

palladium

drug development

6-keto-pgf1alpha

automobile

pghs-2

prostaglandin-endoperoxide

e-prostanoid

ictal

pge2-dependent

l-pgds

15-hydroxyprostaglandin

lipocalin-type

akr1b1

cox-2-dependent

6-keto

coxibs

6-keto-pgf1

ptgds

cox-derived

Reaction

(13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate

(13E)-(15S)-15-hydroxy-9-oxoprosta-11,13-dienoate

Synonyms

CPGES, cPGES/p23, cytosolic prostaglandin E synthase, cytosolic prostaglandin E(2) synthase, cytosolic prostaglandin E(2) synthase-2, endoperoxide isomerase, Isomerase, prostaglandin R2 E-, membrane-associated PGE2 synthase, membrane-associated prostaglandin E synthase-2, membrane-associated prostaglandin E(2) synthase-1, membrane-associated prostaglandin E(2) synthase-2, microsomal PG synthase-1, microsomal PGE synthase-1, microsomal PGE2 synthase, microsomal PGE2 synthase-1, microsomal prostaglandin E synthase, microsomal prostaglandin E synthase 1, microsomal prostaglandin E synthase type 1, microsomal prostaglandin E synthase type 2, microsomal prostaglandin E synthase type-2, microsomal prostaglandin E synthase-1, microsomal prostaglandin E synthase-2, microsomal prostaglandin E(2) synthase-1, microsomal prostaglandin E(2) synthase-2, microsomal prostaglandin E2 synthase 1, microsomal prostaglandin E2 synthase type 1, microsomal prostaglandin E2 synthase-1, microsomal prostaglandin synthase-1, microsomal prostaglandin-E synthase-1, mPGE synthase-2, mPGES, mPGES-1, mPGES-2, MPGES1, MPGES2, p23, PGE, PGE isomerase, PGE synthase, PGE synthase-1, PGE2, PGE2 isomerase, PGE2 synthase, PGE2-synthase, PGES, PGES-1, PGES-2, PGH-PGE isomerase, PGH2/PGE2 isomerase, prostagandin-E synthetase, Prostaglandin E synthase, prostaglandin E synthase 1, prostaglandin E synthase type 2, prostaglandin E synthase-1, prostaglandin E synthase-2, Prostaglandin E2 isomerase, prostaglandin E2 synthase, prostaglandin E2 synthase-1, prostaglandin E2 synthase-I, Prostaglandin endoperoxide E isomerase, Prostaglandin endoperoxide E2 isomerase, Prostaglandin endoperoxide-E isomerase, Prostaglandin H-E isomerase, Prostaglandin H-prostaglandin E isomerase, Prostaglandin R-prostaglandin E isomerase, prostaglandin synthase-1, prostaglandin-E synthase, Prostaglandin-H2 E-isomerase, PTGES

Results	in table
63	Activating Compound
1790	AA Sequence
25	Application
1	CAS Registry Number
37	Cloned(Commentary)
17	Cofactor
11	Crystallization (Commentary)
2974	Disease/ Diagnostics
15	Expression
29	General Information
6	General Stability
352	IC50 Value
471	Inhibitors
30	KM Value [mM]
108	Localization
23	Molecular Weight [Da]
70	Natural Substrates/ Products (Substrates)
145	Organism
8	Pathway
31	PDB ID
13	pH Optimum
3	pH Range
1	pH Stability
58	Protein Variants
21	Purification (Commentary)
3	Reaction
25	Reaction Type
138	Reference
268	Source Tissue
21	Specific Activity [micromol/min/mg]
6	Storage Stability
130	Substrates and Products (Substrate)
23	Subunits
272	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
6	Turnover Number [1/s]

5.3.99.3: prostaglandin-E synthase

Reaction

Synonyms

ECTree

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Synonyms

Synonyms on EC 5.3.99.3 - prostaglandin-E synthase