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5.3.99.2: Prostaglandin-D synthase

This is an abbreviated version!
For detailed information about Prostaglandin-D synthase, go to the full flat file.

Word Map on EC 5.3.99.2

Reaction

(5Z,13E,15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate
=
(5Z,13E,15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate

Synonyms

beta-Trace, Beta-trace protein, betaTP, glutathione dependent prostaglandine D2 synthase, Glutathione-dependent PGD synthetase, glutathione-dependent prostaglandin D2 synthase, Glutathione-independent PGD synthetase, H-PGDS, haematopoietic PGD synthase, haematopoietic prostaglandin D synthase, Hematopoietic prostaglandin D synthase, hematopoietic prostaglandin D2 synthase, HPGDS, Isomerase, prostaglanin R2 D-, L-PGDS, L-prostaglandin D synthase, L-type prostaglandin synthase, lipocalin prostaglandin D synthase, lipocalin type prostaglandin D synthase, lipocalin-prostaglandin D synthase, lipocalin-type PG D synthase, lipocalin-type PGD synthase, lipocalin-type Pgds, lipocalin-type prostaglandin d synthase, lipocalin-type prostaglandin D2 synthase, lipocaline-type prostaglandin D synthase, PGD synthase, PGD-S, PGD2 synthase, PGD2 synthetase, PGDS, PGDS2, PGH-PGD isomerase, PGH2 D-isomerase, Prostaglandin D synthase, Prostaglandin D2 synthase, prostaglandin D2 synthetase, prostaglandin synthase, Prostaglandin-D synthase, Prostaglandin-H2 D-isomerase, Prostaglandin-R-prostaglandin D isomerase, PTGDS

ECTree

     5 Isomerases
         5.3 Intramolecular oxidoreductases
             5.3.99 Other intramolecular oxidoreductases
                5.3.99.2 Prostaglandin-D synthase

KI Value

KI Value on EC 5.3.99.2 - Prostaglandin-D synthase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.061
11-hydroxy-DELTA9-tetrahydrocannabinol
-
at pH 7.6 and 25°C
0.0078
11-nor-9-carboxy-DELTA9-tetrahydrocannabinol
-
at pH 7.6 and 25°C
0.075
4-dibenzo [a,d]cyclohepten-5-ylidene-1-[4-(2H-tetrazol-5-yl)-butyl]-piperidine
-
pH 8.0
0.0022
ajulemic acid
-
at pH 7.6 and 25°C
0.0779
cannabidiol
-
at pH 7.6 and 25°C
0.175
DELTA9-tetrahydrocannabinol
-
at pH 7.6 and 25°C
0.023
L-thyroxine
-
-
0.0018
oleic acid
-
at pH 7.6 and 25°C
0.0037
palmitoleic acid
-
at pH 7.6 and 25°C
0.128
prostaglandin E2
-
at pH 7.6 and 25°C
0.0112
prostaglandin E2-glyceryl ester
-
at pH 7.6 and 25°C
0.081
prostaglandin F2alpha
-
at pH 7.6 and 25°C
0.001
sanguinarine sulfate
at pH 6.5 and 30°C
0.003
SBFI-26
-
at pH 7.6 and 25°C
0.0001
suramin
at pH 6.5 and 30°C
0.0002
Tannic acid
at pH 6.5 and 30°C