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5.3.99.11: 2-keto-myo-inositol isomerase

This is an abbreviated version!
For detailed information about 2-keto-myo-inositol isomerase, go to the full flat file.

Reaction

2,4,6/3,5-pentahydroxycyclohexanone
=
2D-2,3,5/4,6-pentahydroxycyclohexanone

Synonyms

2KMI isomerase, inosose isomerase, IolI

ECTree

     5 Isomerases
         5.3 Intramolecular oxidoreductases
             5.3.99 Other intramolecular oxidoreductases
                5.3.99.11 2-keto-myo-inositol isomerase

Systematic Name

Systematic Name on EC 5.3.99.11 - 2-keto-myo-inositol isomerase

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SYSTEMATIC NAME
IUBMB Comments
2,4,6/3,5-pentahydroxycyclohexanone 2-isomerase
Requires a divalent metal ion for activity. Mn2+, Fe2+ and Co2+ can be used. The enzyme, found in the bacterium Bacillus subtilis, is part of the myo-inositol/D-chiro-inositol degradation pathway leading to acetyl-CoA.