5.3.3.5: cholestenol DELTA-isomerase

This is an abbreviated version!
For detailed information about cholestenol DELTA-isomerase, go to the full flat file.

Word Map on EC 5.3.3.5

5.3.3.5

ebp

x-linked

chondrodysplasia

punctata

stipple

sigma1

epiphyseal

x-inactivation

8-dehydrocholesterol

nsdhl

Reaction

Synonyms

3beta-hydroxysteroid DELTA8,7-sterol isomerase, 3beta-hydroxysteroid DELTA8-DELTA7 isomerase, 8,7SI, C-8,7 sterol isomerase, Cholestenol delta-isomerase, D8-D7 sterol isomerase, D8D7I, DELTA8,7-isomerase, DELTA8,7-sterol isomerase, DELTA8-Cholestenol-DELTA7-cholestenol isomerase, DELTA8-DELTA7 isomerase, Delta8-delta7 sterol isomerase, DELTA8-SI, EBP, Emopamil binding protein, emopamil-binding protein, ERG2p, HSI, Isomerase, cholestenol DELTA-, SI, SI1, sterol 8,7-isomerase, sterol DELTA8 isomerase

ECTree

5 Isomerases

5.3 Intramolecular oxidoreductases

5.3.3 Transposing C=C bonds

5.3.3.5 cholestenol DELTA-isomerase

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Results	in table
38	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
53	Disease/ Diagnostics
1	General Information
34	IC50 Value
229	Inhibitors
104	Ki Value [mM]
4	KM Value [mM]
4	Localization
7	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
22	Organism
14	Pathway
6	PDB ID
1	pH Optimum
1	pI Value
81	Protein Variants
1	Purification (Commentary)
1	Reaction
2	Reaction Type
22	Reference
4	Source Tissue
1	Specific Activity [micromol/min/mg]
1	Storage Stability
32	Substrates and Products (Substrate)
5	Subunits
48	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 5.3.3.5 - cholestenol DELTA-isomerase

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5alpha-cholest-7-en-3beta-ol

Rattus norvegicus

Q9JJ46

enzyme of the cholesterol biosynthetic pathway, mutations are associated with Conradi-Huenermann syndrome. The enzyme may be involved in liver function, since the mRNA is only detected in hepatocytes not in connective tissue or blood vessels. The expression of the SI gene is regulated transcriptionally in vitro and in vivo by widely known regulatory agents ranging from tamoxifen, an oestrogen receptor antagonist and SI-specific inhibitor, to cholesterol-lowering drugs

649702

zymostenol

lathosterol

4 entries

zymosterol

cholesta-7,24-dienol

5 entries