5.3.3.5: cholestenol DELTA-isomerase
This is an abbreviated version!
For detailed information about cholestenol DELTA-isomerase, go to the full flat file.
Word Map on EC 5.3.3.5
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5.3.3.5
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ebp
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x-linked
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chondrodysplasia
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punctata
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stipple
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sigma1
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epiphyseal
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x-inactivation
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8-dehydrocholesterol
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nsdhl
- 5.3.3.5
- ebp
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x-linked
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chondrodysplasia
- punctata
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stipple
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sigma1
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epiphyseal
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x-inactivation
- 8-dehydrocholesterol
- nsdhl
Reaction
Synonyms
3beta-hydroxysteroid DELTA8,7-sterol isomerase, 3beta-hydroxysteroid DELTA8-DELTA7 isomerase, 8,7SI, C-8,7 sterol isomerase, Cholestenol delta-isomerase, D8-D7 sterol isomerase, D8D7I, DELTA8,7-isomerase, DELTA8,7-sterol isomerase, DELTA8-Cholestenol-DELTA7-cholestenol isomerase, DELTA8-DELTA7 isomerase, Delta8-delta7 sterol isomerase, DELTA8-SI, EBP, Emopamil binding protein, emopamil-binding protein, ERG2p, HSI, Isomerase, cholestenol DELTA-, SI, SI1, sterol 8,7-isomerase, sterol DELTA8 isomerase
ECTree
5.3.3.5 cholestenol DELTA-isomeraseAdvanced search results
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results (Engineering
Engineering on EC 5.3.3.5 - cholestenol DELTA-isomerase
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PROTEIN VARIANTS 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
C121A
mutant enzyme with 95% of the in vivo activity of the wild-type enzyme
C128A
mutant enzyme with 81% of the in vivo activity of the wild-type enzyme
C68A
mutant enzyme with 94% of the in vivo activity of the wild-type enzyme
C73A
mutant enzyme with 83% of the in vivo activity of the wild-type enzyme
E123A
mutant enzyme with 10% of the in vivo activity of the wild-type enzyme
E81A
mutant enzyme with 5% of the in vivo activity of the wild-type enzyme
F186A
mutant enzyme with 56% of the in vivo activity of the wild-type enzyme
F188A
mutant enzyme with 94% of the in vivo activity of the wild-type enzyme
F190A
mutant enzyme with 21% of the in vivo activity of the wild-type enzyme
F192A
mutant enzyme with 92% of the in vivo activity of the wild-type enzyme
F37A
mutant enzyme with 74% of the in vivo activity of the wild-type enzyme
F70A
mutant enzyme with 95% of the in vivo activity of the wild-type enzyme
F75A
mutant enzyme with 88% of the in vivo activity of the wild-type enzyme
F84A
mutant enzyme with 72% of the in vivo activity of the wild-type enzyme
G131A
mutant enzyme with 69% of the in vivo activity of the wild-type enzyme
G41A
mutant enzyme with 94% of the in vivo activity of the wild-type enzyme
G82A/F84V
mutant enzyme with 56% of the in vivo activity of the wild-type enzyme
H31A
mutant enzyme with 69% of the in vivo activity of the wild-type enzyme
H77A
mutant enzyme with 9% of the in vivo activity of the wild-type enzyme
I125A
mutant enzyme with 78% of the in vivo activity of the wild-type enzyme
I139A
mutant enzyme with 90% of the in vivo activity of the wild-type enzyme
I32A
mutant enzyme with 73% of the in vivo activity of the wild-type enzyme
I76A
mutant enzyme with 33% of the in vivo activity of the wild-type enzyme
I76L/L78A
mutant enzyme with 74% of the in vivo activity of the wild-type enzyme
L129A
mutant enzyme with 81% of the in vivo activity of the wild-type enzyme
L133A
mutant enzyme with 77% of the in vivo activity of the wild-type enzyme
L135A
mutant enzyme with 92% of the in vivo activity of the wild-type enzyme
L196A
mutant enzyme with 62% of the in vivo activity of the wild-type enzyme
L198A
mutant enzyme with 50% of the in vivo activity of the wild-type enzyme
L204A
mutant enzyme with 77% of the in vivo activity of the wild-type enzyme
L33A
mutant enzyme with 47% of the in vivo activity of the wild-type enzyme
L35A
mutant enzyme with 62% of the in vivo activity of the wild-type enzyme
L43A
mutant enzyme with 103% of the in vivo activity of the wild-type enzyme
L49A
mutant enzyme with 108% of the in vivo activity of the wild-type enzyme
L50A
mutant enzyme with 96% of the in vivo activity of the wild-type enzyme
L65A
mutant enzyme with 82% of the in vivo activity of the wild-type enzyme
L67A
mutant enzyme with 63% of the in vivo activity of the wild-type enzyme
M122A
mutant enzyme with 28% of the in vivo activity of the wild-type enzyme
M193A
mutant enzyme with 53% of the in vivo activity of the wild-type enzyme
S134A
mutant enzyme with 101% of the in vivo activity of the wild-type enzyme
S38A
mutant enzyme with 74% of the in vivo activity of the wild-type enzyme
T124A
mutant enzyme with 91% of the in vivo activity of the wild-type enzyme
T126A
mutant enzyme with 4% of the in vivo activity of the wild-type enzyme
V120A
mutant enzyme with 62% of the in vivo activity of the wild-type enzyme
V138A
mutant enzyme with 94% of the in vivo activity of the wild-type enzyme
V191A
mutant enzyme with 91% of the in vivo activity of the wild-type enzyme
V199A
mutant enzyme with 76% of the in vivo activity of the wild-type enzyme
V203A
mutant enzyme with 71% of the in vivo activity of the wild-type enzyme
V39A
mutant enzyme with 80% of the in vivo activity of the wild-type enzyme
V44A
mutant enzyme with 76% of the in vivo activity of the wild-type enzyme
V45A
mutant enzyme with 79% of the in vivo activity of the wild-type enzyme
V72A
mutant enzyme with 93% of the in vivo activity of the wild-type enzyme
V79A
mutant enzyme with 75% of the in vivo activity of the wild-type enzyme
V85A
mutant enzyme with 68% of the in vivo activity of the wild-type enzyme
W130A
mutant enzyme with 70% of the in vivo activity of the wild-type enzyme
W136A
mutant enzyme with 104% of the in vivo activity of the wild-type enzyme
W187A
mutant enzyme with 56% of the in vivo activity of the wild-type enzyme
W197A
mutant enzyme with 5% of the in vivo activity of the wild-type enzyme
W48A
mutant enzyme with 87% of the in vivo activity of the wild-type enzyme
W69A
mutant enzyme with 17% of the in vivo activity of the wild-type enzyme
W83A
mutant enzyme with 97% of the in vivo activity of the wild-type enzyme
Y185A
mutant enzyme with 64% of the in vivo activity of the wild-type enzyme
Y189A
mutant enzyme with 32% of the in vivo activity of the wild-type enzyme
additional information
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functional complementation by C-8,7 sterol isomerase of the corresponding sterol mutant in yeast and its characterization by exposure to sigma ligands. The full-length Arabidosis thaliana cDNA encoding C-8,7 sterol isomerase complements the erg2 mutation
