5.3.3.14: trans-2-decenoyl-[acyl-carrier protein] isomerase
This is an abbreviated version!
For detailed information about trans-2-decenoyl-[acyl-carrier protein] isomerase, go to the full flat file.
Reaction
Synonyms
FabM
ECTree
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Inhibitors
Inhibitors on EC 5.3.3.14 - trans-2-decenoyl-[acyl-carrier protein] isomerase
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additional information
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not inhibitory: iodoacetic acid, chloroacetic acid, iodoacetamide, N-ethylmaleimide
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covalent modification of ative site residue H70
3-decynoyl-N-acetylcysteamine
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strong inhibition of both dehydrase activity of EC 4.2.1.60 and isomerase activity of enzyme
3-decynoyl-N-acetylcysteamine
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irreversible inactivation of both dehydrase activity of EC 4.2.1.60 and isomerase activity of enzyme, inhibition occurs through isomerization to the allene and subsequent covalent modification of enzyme