Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

5.3.3.12: L-dopachrome isomerase

This is an abbreviated version!
For detailed information about L-dopachrome isomerase, go to the full flat file.

Word Map on EC 5.3.3.12

Reaction

L-Dopachrome
=
5,6-Dihydroxyindole-2-carboxylate

Synonyms

brown (b) locus protein, D-dopachrome isomerase, D-dopachrome tautomerase, D-DT, DCF, DCT, DDT, dopachrome conversion factor, dopachrome delta-isomerase, dopachrome DELTA7-DELTA2-isomerase, dopachrome oxidoreductase, dopachrome tautomerase, dopachrome-rearranging enzyme, isomerase, dopachrome DELTA-, L-dopachchrome-methyl ester tautomerase, macrophage inhibitory factor, Macrophage migration inhibitory factor, macrophage migration-inhibitory factor, MIF, Mif-2, SLATY locus protein, TRP-2, TRP2, tyrosine-related protein 2

ECTree

     5 Isomerases
         5.3 Intramolecular oxidoreductases
             5.3.3 Transposing C=C bonds
                5.3.3.12 L-dopachrome isomerase

Cloned

Cloned on EC 5.3.3.12 - L-dopachrome isomerase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
Dct genotyping
-
DNA and amino acid sequence determination of the tyrosinase-related protein2/DOPAchrome tautomerase gene, polymorphism analysis, overview
-
expressed in HEK-293 cells
-
expression in Escherichia coli strain BL21(DE3)
-
expression of the truncated enzyme lacking its carboxy-terminal transmembrane region in Spodoptera frugiperda Sf9 insect cell using a viral transfer vector
-
gene mif
-
genotyping of healthy and autoimmune vitiligo individuals, overview
-
overexpressed in WM35 melanoma cell line as model system, endogenously expressing low levels of TRP-2. TRP-2 specifically decreases WM35 cell sensitivity to oxidative stress. Overexpreesion of enzyme in HEK-293 cells has no influence on cell sensitivity to oxidative stress
-
recombinant expression of MIF in HeLa cells and in Escherichia coli strain BL21(DE3)
-