5.3.2.3: TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming)

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For detailed information about TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming), go to the full flat file.

Reaction

Synonyms

dTDP-6-deoxy-D-xylo-hexos-4-ulose 3,4-ketoisomerase, FdtA, RavIM, TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase

ECTree

     5 Isomerases

         5.3 Intramolecular oxidoreductases

             5.3.2 Interconverting keto- and enol-groups

                5.3.2.3 TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming)

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Results	in table
201	AA Sequence
1	Application
4	Cloned(Commentary)
2	Crystallization (Commentary)
1	General Stability
5	kcat/KM [mM/s]
5	KM Value [mM]
1	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
8	Organism
6	Pathway
3	pH Optimum
10	Protein Variants
4	Purification (Commentary)
1	Reaction
8	Reference
1	Storage Stability
13	Substrates and Products (Substrate)
3	Subunits
9	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
5	Turnover Number [1/s]

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Application on EC 5.3.2.3 - TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming)

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

synthesis

Streptomyces ravidus

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synthesis of TDP-D-ravidosamine, necessary for in vitro glycosylation assays. TDP-D-ravidosamine is the anticipated sugar donor substrate of RavGT (the glycosyltransferase that links D-ravidosamine to the polyketide derived backbone defuco-gilvocarcin V). Defuco-gilvocarcin V exhibits superior anticancer/antibacterial activities

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