5.3.2.2: oxaloacetate tautomerase

This is an abbreviated version!
For detailed information about oxaloacetate tautomerase, go to the full flat file.

Reaction

Synonyms

High-molecular mass oxalacetate tautomerase, OAA tautomerase, OAT, OAT-1, OAT-2, Oxalacetic keto-enol isomerase, Oxaloacetate keto-enol tautomerase, Oxaloacetate tautomerase-1, Oxaloacetate tautomerase-2, Tautomerase, oxalacetate

ECTree

     5 Isomerases

         5.3 Intramolecular oxidoreductases

             5.3.2 Interconverting keto- and enol-groups

                5.3.2.2 oxaloacetate tautomerase

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Results	in table
1	Activating Compound
14	AA Sequence
1	CAS Registry Number
1	General Stability
33	Inhibitors
6	KM Value [mM]
10	Localization
2	Metals/Ions
5	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
8	Organism
23	PDB ID
2	pH Optimum
2	pH Range
4	pH Stability
3	Purification (Commentary)
1	Reaction
2	Reaction Type
8	Reference
8	Source Tissue
1	Specific Activity [micromol/min/mg]
2	Storage Stability
12	Substrates and Products (Substrate)
4	Subunits
10	Synonyms
1	Systematic Name
3	Temperature Stability [°C]
5	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 5.3.2.2 - oxaloacetate tautomerase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

2-oxoglutarate

Sus scrofa

-

-

2874

acetoacetate

Sus scrofa

-

-

2874

citrate

Sus scrofa

-

-

2874

CuCl2

Sus scrofa

-

-

2874

Diethyloxaloacetate

Sus scrofa

-

-

2874

diphosphate

3 entries

DL-isocitrate

Bos taurus

-

inhibits enzyme form OAT-2

2878

DL-malic acid

Sus scrofa

-

-

2874

Fluorocitrate

2 entries

HgCl2

Sus scrofa

-

-

2874

KCl

Sus scrofa

-

-

2874

Lactate

Sus scrofa

-

-

2874

LiCl

Sus scrofa

-

-

2874

Maleate

2 entries

malonate

2 entries

MgCl2

Sus scrofa

-

-

2874

NaCl

Sus scrofa

-

-

2874

NEM

2 entries

oxalate

2 entries

Oxaloacetic acid diethylester

Bos taurus

-

enzyme form OAT-1 is inhibited, enzyme form OAT-2 not

2879

PCMB

Sus scrofa

-

-

2874

phenylpyruvate

Bos taurus

-

enzyme form OAT-2 is inhibited, enzyme form OAT-1 not

2879

phosphoenolpyruvate

Bos taurus

-

enzyme form OAT-2 is inhibited, enzyme form OAT-1 not

2879

pyruvate

Sus scrofa

-

-

2874

Urea

Sus scrofa

-

-

2874

ZnCl2

Sus scrofa

-

-

2874

diphosphate

Bos taurus

-

enzyme form OAT-2 is inhibited, enzyme form OAT-1 not

2877

diphosphate

Bos taurus

-

-

2878

diphosphate

Bos taurus

-

enzyme form OAT-2 is inhibited, enzyme form OAT-1 not

2879

Fluorocitrate

Bos taurus

-

inhibition of OAT-2, tautomerase reaction and aconitase reaction

2877

Fluorocitrate

Bos taurus

-

-

2878

Maleate

Bos taurus

-

enzyme form OAT-2 is inhibited, enzyme form OAT-1 not

2877

Maleate

Bos taurus

-

-

2879

malonate

Bos taurus

-

enzyme form OAT-2 is inhibited, enzyme form OAT-1 not

2879

malonate

Sus scrofa

-

-

2874

NEM

Bos taurus

-

enzyme form OAT-2 is inhibited, enzyme form OAT-1 not

2877

NEM

Bos taurus

-

enzyme form OAT-2: irreversible loss of oxaloacetate keto-enol tautomerase activity and aconitase activity

2878

oxalate

Bos taurus

-

enzyme form OAT-1 is inhibited, enzyme form OAT-2 not

2877

oxalate

Bos taurus

-

-

2879