5.3.1.9: glucose-6-phosphate isomerase

This is an abbreviated version!
For detailed information about glucose-6-phosphate isomerase, go to the full flat file.

Reaction

Synonyms

6-Phosphoglucose isomerase, AfcPGI, AMF, AMF/PGI, At4g24620, autocrine motility factor, autocrine motility factor/phosphoglucose isomerase, Cupin-PGI, D-Glucose-6-phosphate isomerase, D-glucose-6-phosphate ketol-isomerase, G6-PI, Glucose 6-phosphate isomerase, Glucose phosphate isomerase, Glucose phosphoisomerase, glucose-6-phosphate isomerase, glucose-6-phosphate isomerase, cytosolic, Glucosephosphate isomerase 2, GPI, Hexose 6-phosphate isomerase, Hexose isomerase, Hexose monophosphate isomerase, Hexose phosphate isomerase, Hexosephosphate isomerase, Isomerase, glucose phosphate, Neuroleukin, NLK, Oxoisomerase, PGI, PGI/AMF, Pgi1, PGI2, PGI3, pgiA, PHI, Phosphoglucoisomerase, Phosphoglucose isomerase, phosphoglucose isomerase/autocrine motility factor, Phosphohexoisomerase, Phosphohexomutase, Phosphohexose isomerase, Phosphosaccharomutase, SA-36, Sperm antigen-36, SwoM, TK1111, VEG54, Vegetative protein 54

ECTree

     5 Isomerases

         5.3 Intramolecular oxidoreductases

             5.3.1 Interconverting aldoses and ketoses, and related compounds

                5.3.1.9 glucose-6-phosphate isomerase

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Results	in table
1	Activating Compound
49706	AA Sequence
14	Application
1	CAS Registry Number
33	Cloned(Commentary)
25	Crystallization (Commentary)
2172	Disease/ Diagnostics
4	Expression
26	General Information
3	General Stability
4	IC50 Value
151	Inhibitors
37	kcat/KM [mM/s]
42	Ki Value [mM]
180	KM Value [mM]
26	Localization
21	Metals/Ions
105	Molecular Weight [Da]
33	Natural Substrates/ Products (Substrates)
547	Organism
1	Oxidation Stability
34	Pathway
183	PDB ID
38	pH Optimum
8	pH Range
4	pH Stability
2	pI Value
1	Posttranslational Modification
69	Protein Variants
62	Purification (Commentary)
7	Reaction
3	Reaction Type
154	Reference
3	Renatured (Commentary)
69	Source Tissue
37	Specific Activity [micromol/min/mg]
7	Storage Stability
146	Substrates and Products (Substrate)
69	Subunits
110	Synonyms
1	Systematic Name
24	Temperature Optimum [°C]
6	Temperature Range [°C]
47	Temperature Stability [°C]
74	Turnover Number [1/s]

General Stability

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General Stability on EC 5.3.1.9 - glucose-6-phosphate isomerase

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

immobilization increases the stability against urea

Oryctolagus cuniculus

-

2849

phosphoglucose isomerase in Tris-HCl buffer has 30% lower observed activity than that in the HEPES buffer at pH 7.0. At working conditions (100 mM HEPES buffer (pH 7.5) containing 10 mM Mg2+ and 0.5 mM Mn2+ at 60°C), no significant activity is lost after 50 washings of immobilized cellulose-binding module-phosphoglucose isomerase

Acetivibrio thermocellus

-

714592

the most basic of the five isoenzymes is more stable than the more acidic isoenzymes at pH extremes, at high ionic strength, in the presence of denaturants, or upon exposure to proteases

Bos taurus

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2851