5.3.1.5: xylose isomerase

This is an abbreviated version!
For detailed information about xylose isomerase, go to the full flat file.

Reaction

Synonyms

D-XI, D-xylose aldose-ketose-isomerase, D-xylose isomerase, D-Xylose ketoisomerase, D-xylose ketol isomerase, D-xylose ketol-isomerase, D-xylose: ketol-isomerase, D-xylulose keto-isomerase, glucose isomerase, glucose/xylose isomerase, GXI, Isomerase, xylose, Maxazyme, Optisweet, SDXyI, Spezyme, Sweetase, Sweetzyme, Sweetzyme Q, Swetase, T80 xylose isomerase, TcaXI, TNXI, TthXI, XI, XYLA, XylC, xylose (glucose) isomerase, xylose isomerase

ECTree

     5 Isomerases

         5.3 Intramolecular oxidoreductases

             5.3.1 Interconverting aldoses and ketoses, and related compounds

                5.3.1.5 xylose isomerase

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Results	in table
4	Activating Compound
16677	AA Sequence
36	Application
1	CAS Registry Number
62	Cloned(Commentary)
34	Crystallization (Commentary)
2	Expression
3	General Information
9	General Stability
108	Inhibitors
44	kcat/KM [mM/s]
5	Ki Value [mM]
168	KM Value [mM]
2	Localization
124	Metals/Ions
66	Molecular Weight [Da]
63	Natural Substrates/ Products (Substrates)
4	Organic Solvent Stability
360	Organism
6	Pathway
335	PDB ID
56	pH Optimum
22	pH Range
23	pH Stability
1	pI Value
2	Posttranslational Modification
100	Protein Variants
60	Purification (Commentary)
1	Reaction
44	Reaction Type
237	Reference
2	Source Tissue
98	Specific Activity [micromol/min/mg]
2	Storage Stability
355	Substrates and Products (Substrate)
55	Subunits
130	Synonyms
1	Systematic Name
46	Temperature Optimum [°C]
18	Temperature Range [°C]
56	Temperature Stability [°C]
117	Turnover Number [1/s]

Organism

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Organism on EC 5.3.1.5 - xylose isomerase

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ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

Actinomyces olivocinereus

-

2766

-

-

brenda

Actinoplanes missouriensis

4 entries

Actinoplanes sp.

-

2766

-

-

brenda

Aerobacter levanicum

-

2766

-

-

brenda

Aeromonas hydrophila

-

2766

-

-

brenda

Arthrobacter sp.

-

2759, 2765, 2766, 2767, 2768, 2771, 2773

-

-

brenda

Bacillus licheniformis

-

2766, 661686

-

-

brenda

Bacillus sp. (in: Bacteria)

3 entries

Bacillus sp. (in: Bacteria) No. KX-6

No. KX-6

2747

-

-

brenda

Bacillus sp. (in: Bacteria) TX-3

TX-3

2774

-

-

brenda

Bacteroides stercoris

-

713924

-

-

brenda

Bacteroides stercoris HJ-15

-

713924

-

-

brenda

Bacteroides thetaiotaomicron

-

726628

Q8A9M2

UniProt

brenda

Bacteroides thetaiotaomicron DSM 2079

-

726628

Q8A9M2

UniProt

brenda

Bifidobacterium adolescentis

2 entries

Brevibacterium helvolum

-

2766

-

-

brenda

Brevibacterium pentosoaminoacidicum

-

2766

-

-

brenda

Burkholderia cenocepacia

-

727184

-

-

brenda

Ciona intestinalis

-

701444

-

-

brenda

Citrobacter freundii

-

2766

-

-

brenda

Citrobacter intermedius

-

2766

-

-

brenda

Clostridium cellulovorans

-

747399

D9SR73

UniProt

brenda

Clostridium cellulovorans DSM 3052

-

747399

D9SR73

UniProt

brenda

Corynebacterium sp.

-

2766

-

-

brenda

Deamia testudo

-

691766, 716725

-

-

brenda

Desemzia incerta

-

2766

-

-

brenda

Enterobacter cloacae

-

2766

-

-

brenda

Escherichia coli

5 entries

Escherichia coli DH5-alpha

strain DH5alpha

673762

-

-

brenda

Escherichia coli HB101xylA

-

671399

-

-

brenda

Escherichia coli K-12

-

706476

-

-

brenda

Geobacillus stearothermophilus

-

2739

-

-

brenda

Glutamicibacter nicotianae

-

671399, 713809

-

-

brenda

Glutamicibacter nicotianae BIM B-5

-

671399

-

-

brenda

Glutamicibacter nicotianae BIM V-5

-

713809

-

-

brenda

Gordonia rubripertincta

-

2766

-

-

brenda

Hordeum vulgare

barley

2760

-

-

brenda

Klebsiella aerogenes

-

2766

-

-

brenda

Lachnoclostridium phytofermentans

-

701788

-

-

brenda

Lactiplantibacillus pentosus

-

2766

-

-

brenda

Lactiplantibacillus plantarum

-

2766

-

-

brenda

Lactobacillus gayonii

-

2766

-

-

brenda

Lactobacillus lycopersici

-

2766

-

-

brenda

Lactobacillus mannitopoeus

-

2766

-

-

brenda

Lactococcus lactis

-

660752

-

-

brenda

Lactococcus lactis 210 (Xyl-)

-

660752

-

-

brenda

Lactococcus lactis IO-1 (Xyl+)

-

660752

-

-

brenda

Lactococcus lactis subsp. lactis

-

2738

-

-

brenda

Lentilactobacillus buchneri

-

2766

-

-

brenda

Leuconostoc mesenteroides

-

2766

-

-

brenda

Levilactobacillus brevis

-

2736, 2738

-

-

brenda

Limosilactobacillus fermentum

-

2766

-

-

brenda

Limosilactobacillus reuteri

-

727658

-

-

brenda

Limosilactobacillus reuteri DSM Z 17509

-

727658

-

-

brenda

Microbacterium arborescens

-

2766

-

-

brenda

Microbispora rosea

-

2766

-

-

brenda

Micromonospora coerulea

-

2766

-

-

brenda

Mycobacterium sp.

-

2766

-

-

brenda

no activity in Corynebacterium glutamicum

-

703500

-

-

brenda

no activity in Hansenula polymorpha

-

673762

-

-

brenda

no activity in Hansenula polymorpha CBS4732s leu2-2

-

673762

-

-

brenda

no activity in Saccharomyces cerevisiae

-

671181

-

-

brenda

Nocardia asteroides

-

2766

-

-

brenda

Nocardiopsis dassonvillei

-

2766

-

-

brenda

Opuntia ficus-indica

-

713800

-

-

brenda

Opuntia vulgaris

-

713800

-

-

brenda

Orpinomyces sp.

-

690595, 690596

B7SLY1

UniProt

brenda

Paenarthrobacter ureafaciens

induced by presence of xylose and xylite. The synthesis of enzyme is controlled by catabolite repression occuring at the transcriptional level and mediated by cyclic 3',5'-AMP

694047

-

-

brenda

Paraburkholderia sacchari

gene xylA

702992

B6VCW7

Uniprot

brenda

Paraburkholderia sacchari IPT101

gene xylA

702992

B6VCW7

Uniprot

brenda

Paracolobacterium aerogenoides

-

2766

-

-

brenda

Pectobacterium atrosepticum

-

671399

-

-

brenda

Pectobacterium atrosepticum jn42xylA

-

671399

-

-

brenda

Piromyces sp.

4 entries

Piromyces sp. E2

-

749350

Q9P8C9

UniProt

brenda

Priestia megaterium

-

2766

-

-

brenda

Pseudonocardia sp.

-

2766

-

-

brenda

Saccharomyces cerevisiae

3 entries

Sarcina sp.

-

2766

-

-

brenda

Scheffersomyces stipitis

gene XYL1

703500

-

-

brenda

Sphingomonas paucimobilis

-

2766

-

-

brenda

Streptococcus venuceus

-

2766

-

-

brenda

Streptomyces achromogenes

-

2766

-

-

brenda

Streptomyces albus

2 entries

Streptomyces albus NRRL 5778

NRRL 5778

2735

-

-

brenda

Streptomyces bikiniensis

-

2766

-

-

brenda

Streptomyces bobili

-

2766

-

-

brenda

Streptomyces californicus

-

2766

-

-

brenda

Streptomyces coelicolor

recombinant enzyme from Hansenula polymorpha transformants

661804

-

-

brenda

Streptomyces corchorusii

-

660647, 662603

-

-

brenda

Streptomyces corchorusii J-59

-

660647, 662603

-

-

brenda

Streptomyces diastaticus No. 7

-

649115

-

-

brenda

Streptomyces diastaticus No. 7 M1033

-

649115

-

-

brenda

Streptomyces echinatus

-

2766

-

-

brenda

Streptomyces flaveus

-

2766

-

-

brenda

Streptomyces flavogriseus

-

2740

-

-

brenda

Streptomyces flavovirens

-

2766

-

-

brenda

Streptomyces fradiae

-

2766

-

-

brenda

Streptomyces glaucescens

-

2766

-

-

brenda

Streptomyces griseofuscus

-

2766

-

-

brenda

Streptomyces griseolus

-

2766

-

-

brenda

Streptomyces griseus

-

2766

-

-

brenda

Streptomyces matensis

-

2766

-

-

brenda

Streptomyces nivens

-

2766

-

-

brenda

Streptomyces olivaceus

-

2766

-

-

brenda

Streptomyces olivochromogenes

2 entries

Streptomyces phaeochromogenes

-

2756, 2766, 658891

-

-

brenda

Streptomyces platensis

-

2766

-

-

brenda

Streptomyces roseochromogenus

-

2766

-

-

brenda

Streptomyces rubiginosus

6 entries

Streptomyces sp.

3 entries

Streptomyces sp. 1

-

653167

-

-

brenda

Streptomyces sp. 32

-

653167

-

-

brenda

Streptomyces sp. NCIM 2730

NCIM 2730

2750, 651082

-

-

brenda

Streptomyces venezuelae

-

2766

-

-

brenda

Streptomyces violaceoruber

-

2746

-

-

brenda

Streptomyces virginiae

-

2766

-

-

brenda

Streptomyces viridobrunneus

-

653167

-

-

brenda

Streptomyces wedmorensis

-

2766

-

-

brenda

Streptosporangium album

-

2766

-

-

brenda

Streptosporangium vulgare

-

2766

-

-

brenda

Thermoanaerobacter ethanolicus

-

714586

D2DK62

UniProt

brenda

Thermoanaerobacter ethanolicus JW200 (ATCC 31550)

-

714586

D2DK62

UniProt

brenda

Thermoanaerobacter thermohydrosulfuricus

-

2766

-

-

brenda

Thermoanaerobacterium saccharolyticum

2 entries

Thermoanaerobacterium saccharolyticum B6A-RI

B6A-RI

2752

-

-

brenda

Thermoanaerobacterium saccharolyticum JW/SL-YS 489

-

2752

-

-

brenda

Thermoanaerobacterium thermosulfurigenes

-

2761, 2766, 2769, 661686

-

-

brenda

Thermopolyspora sp.

-

2766

-

-

brenda

Thermotoga neapolitana

2 entries

Thermotoga neapolitana 5068

-

714591

-

-

brenda

Thermus aquaticus

-

2755, 2772

-

-

brenda

Thermus aquaticus HB8

-

2755, 2772

-

-

brenda

Thermus caldophilus

-

649109, 652795

-

-

brenda

Thermus thermophilus

6 entries

Thermus thermophilus HB8 / ATCC 27634 / DSM 579

2 entries

Vibrio sp.

-

716090

C7G532

UniProt

brenda

Vibrio sp. XY-214

-

716090

C7G532

UniProt

brenda

Weizmannia coagulans

-

2731, 2732, 2733, 2766, 658891

-

-

brenda

Weizmannia coagulans HN-68

-

2731, 2732, 2733

-

-

brenda

Xanthomonas sp.

-

2766

-

-

brenda

Zymomonas mobilis

-

2766

-

-

brenda

Actinoplanes missouriensis

-

2762, 2763, 2766, 658891

-

-

brenda

Actinoplanes missouriensis

-

661268

P12851

Uniprot

brenda

Actinoplanes missouriensis

-

663282

-

-

brenda

Actinoplanes missouriensis

expressed in Escherichia coli

2753

-

-

brenda

Bacillus sp. (in: Bacteria)

-

2744, 2758

-

-

brenda

Bacillus sp. (in: Bacteria)

No. KX-6

2747

-

-

brenda

Bacillus sp. (in: Bacteria)

TX-3

2774

-

-

brenda

Bifidobacterium adolescentis

-

2756

-

-

brenda

Bifidobacterium adolescentis

-

726633

A1A0H0

UniProt

brenda

Escherichia coli

-

2742, 2745, 2766, 661686, 671399, 671487, 673762, 690541

-

-

brenda

Escherichia coli

recombinant enzyme from Hansenula polymorpha transformants

661804

-

-

brenda

Escherichia coli

source of genes encoding xylose isomerase (xylA) and xylulokinase (xylB)

671459

-

-

brenda

Escherichia coli

strain DH5alpha

673762

-

-

brenda

Escherichia coli

transformed strain LE392-pRK248/pTXI-1, that overproduces the enzyme by induction of the strong lambda PI promoter

2749

-

-

brenda

Piromyces sp.

-

675810, 701788, 726727

-

-

brenda

Piromyces sp.

gene xylA

703769

-

-

brenda

Piromyces sp.

recombinant enzyme, expressed in Saccharomyces cerevisiae

661806

-

-

brenda

Piromyces sp.

source of xylose isomerase gene, a phylogenetic tree of the diversity of xylose isomerase genes is given - based on GenBank database

671181

-

-

brenda

Saccharomyces cerevisiae

-

705436

-

-

brenda

Saccharomyces cerevisiae

designed strain TMB 3045, carrying the XI gene from Thermus thermophilus

663450

-

-

brenda

Saccharomyces cerevisiae

strain TMB 3050, derived from strain TMB 3045, which carries the XI gene from Thermus thermophilus

663450

-

-

brenda

Streptomyces albus

-

2737

-

-

brenda

Streptomyces albus

NRRL 5778

2735

-

-

brenda

Streptomyces olivochromogenes

-

2739, 2748, 2764, 2766, 2770

-

-

brenda

Streptomyces olivochromogenes

-

661142

P15587

Uniprot

brenda

Streptomyces rubiginosus

-

2741, 2766, 652625, 652772, 653233, 658891, 660597, 661385

-

-

brenda

Streptomyces rubiginosus

-

663282

P24300

UniProt

brenda

Streptomyces rubiginosus

-

673423, 673424

-

-

brenda

Streptomyces rubiginosus

-

676870, 690979, 693837, 716936, 726953

P24300

UniProt

brenda

Streptomyces rubiginosus

-

728730

-

-

brenda

Streptomyces rubiginosus

-

746622, 749383

P24300

UniProt

brenda

Streptomyces sp.

-

2734, 2743, 2751

-

-

brenda

Streptomyces sp.

NCIM 2730

2750, 651082

-

-

brenda

Streptomyces sp.

thermophilic strain PLC

2754

-

-

brenda

Thermoanaerobacterium saccharolyticum

-

2752

-

-

brenda

Thermoanaerobacterium saccharolyticum

B6A-RI

2752

-

-

brenda

Thermotoga neapolitana

-

2757, 661686, 714591

-

-

brenda

Thermotoga neapolitana

-

745533

P45687

SwissProt

brenda

Thermus thermophilus

-

2766, 651118, 651814, 652795

-

-

brenda

Thermus thermophilus

-

703492

P26997

UniProt

brenda

Thermus thermophilus

-

713691

-

-

brenda

Thermus thermophilus

-

728722

P26997

UniProt

brenda

Thermus thermophilus

-

746869

-

-

brenda

Thermus thermophilus

source of xylose isomerase gene, a phylogenetic tree of the diversity of xylose isomerase genes is given - based on GenBank database

671181

-

-

brenda

Thermus thermophilus HB8 / ATCC 27634 / DSM 579

-

713691

-

-

brenda

Thermus thermophilus HB8 / ATCC 27634 / DSM 579

-

728722

P26997

UniProt

brenda