5.3.1.24: phosphoribosylanthranilate isomerase

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For detailed information about phosphoribosylanthranilate isomerase, go to the full flat file.

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Synonyms

IGPS:PRAI (indole-3-glycerol-phosphate synthetase/N-5'-phosphoribosylanthranilate isomerase complex), isomerase, phosphoribosylanthranilate, More, N-(5'-phosphoribosyl)anthranilate isomerase, N-(5'-phosphoribosyl)anthranilate isomerase/dehydratase, N-(5-phospho-beta-D-ribosyl)anthranilate ketol-isomerase, N-5�-phosphoribosylanthranilate isomerase, PAI, PfTrpF, phosphoribosyl anthranilate isomerase, phosphoribosyl isomerase A, phosphoribosylanthranilate isomerase, PRA isomerase, PRAI, PRAI-LoxP, PRAI[ML256-452], PriA, PurF(I198V), Trp1, Trp1p, TrpF, TrpFCtL2, TtPRAI, xPRAI

ECTree

     5 Isomerases

         5.3 Intramolecular oxidoreductases

             5.3.1 Interconverting aldoses and ketoses, and related compounds

                5.3.1.24 phosphoribosylanthranilate isomerase

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Results	in table
37052	AA Sequence
1	Application
1	CAS Registry Number
32	Cloned(Commentary)
17	Crystallization (Commentary)
4	General Information
7	General Stability
19	Inhibitors
9	kcat/KM [mM/s]
8	Ki Value [mM]
47	KM Value [mM]
36	Molecular Weight [Da]
78	Natural Substrates/ Products (Substrates)
135	Organism
1	Oxidation Stability
6	Pathway
26	PDB ID
8	pH Optimum
4	pH Stability
36	Protein Variants
32	Purification (Commentary)
8	Reaction
27	Reaction Type
75	Reference
3	Source Tissue
11	Specific Activity [micromol/min/mg]
4	Storage Stability
145	Substrates and Products (Substrate)
34	Subunits
52	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
12	Temperature Stability [°C]
44	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 5.3.1.24 - phosphoribosylanthranilate isomerase

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SYSTEMATIC NAME

IUBMB Comments

N-(5-phospho-beta-D-ribosyl)anthranilate aldose-ketose-isomerase

In some organisms, this enzyme is part of a multifunctional protein, together with one or more other components of the system for the biosynthesis of tryptophan [EC 2.4.2.18 (anthranilate phosphoribosyltransferase), EC 4.1.1.48 (indole-3-glycerol-phosphate synthase), EC 4.1.3.27 (anthranilate synthase) and EC 4.2.1.20 (tryptophan synthase)].