5.3.1.24: phosphoribosylanthranilate isomerase

This is an abbreviated version!
For detailed information about phosphoribosylanthranilate isomerase, go to the full flat file.

Word Map on EC 5.3.1.24

5.3.1.24

indoleglycerol

amidotransferase

alpha8

betaalpha8-barrels

dual-substrate

biotechnology

Reaction

N-(5-phospho-beta-D-ribosyl)anthranilate

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate

Synonyms

IGPS:PRAI (indole-3-glycerol-phosphate synthetase/N-5'-phosphoribosylanthranilate isomerase complex), isomerase, phosphoribosylanthranilate, More, N-(5'-phosphoribosyl)anthranilate isomerase, N-(5'-phosphoribosyl)anthranilate isomerase/dehydratase, N-(5-phospho-beta-D-ribosyl)anthranilate ketol-isomerase, N-5�-phosphoribosylanthranilate isomerase, PAI, PfTrpF, phosphoribosyl anthranilate isomerase, phosphoribosyl isomerase A, phosphoribosylanthranilate isomerase, PRA isomerase, PRAI, PRAI-LoxP, PRAI[ML256-452], PriA, PurF(I198V), Trp1, Trp1p, TrpF, TrpFCtL2, TtPRAI, xPRAI

ECTree

5 Isomerases

5.3 Intramolecular oxidoreductases

5.3.1 Interconverting aldoses and ketoses, and related compounds

5.3.1.24 phosphoribosylanthranilate isomerase

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Results	in table
37052	AA Sequence
1	Application
1	CAS Registry Number
32	Cloned(Commentary)
17	Crystallization (Commentary)
4	General Information
7	General Stability
19	Inhibitors
9	kcat/KM [mM/s]
8	Ki Value [mM]
47	KM Value [mM]
36	Molecular Weight [Da]
78	Natural Substrates/ Products (Substrates)
135	Organism
1	Oxidation Stability
6	Pathway
26	PDB ID
8	pH Optimum
4	pH Stability
36	Protein Variants
32	Purification (Commentary)
8	Reaction
27	Reaction Type
75	Reference
3	Source Tissue
11	Specific Activity [micromol/min/mg]
4	Storage Stability
145	Substrates and Products (Substrate)
34	Subunits
52	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
12	Temperature Stability [°C]
44	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 5.3.1.24 - phosphoribosylanthranilate isomerase

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2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

7,8-dihydroneopterin 3'-phosphate + H2O

2 entries

N-(5-phospho-beta-D-ribosyl)anthranilate

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate

74 entries

additional information

Saccharomyces cerevisiae

the enzyme is essential for cell proliferation in the absence of tryptophan

677592