Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

5.2.1.4: maleylpyruvate isomerase

This is an abbreviated version!
For detailed information about maleylpyruvate isomerase, go to the full flat file.

Word Map on EC 5.2.1.4

Reaction

3-maleylpyruvate
=
3-fumarylpyruvate

Synonyms

3-maleylpyruvate cis-trans-isomerase, BagL, HbzG, Isomerase, maleylpyruvate, maleylpyruvate isomerase, MDMPI, MPI, msh gene, mycothiol-dependent maleylpyruvate isomerase, NagL, NarL, ncgl2918 gene, thiol-dependent maleylpyruvate isomerase

ECTree

     5 Isomerases
         5.2 cis-trans-Isomerases
             5.2.1 cis-trans Isomerases (only sub-subclass identified to date)
                5.2.1.4 maleylpyruvate isomerase

Engineering

Engineering on EC 5.2.1.4 - maleylpyruvate isomerase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
C61A
site directed mutagenesis
D151A
site directed mutagenesis, completely inactive
E144A
site directed mutagenesis, completely inactive
E85A
site directed mutagenesis
H148A
site directed mutagenesis, completely inactive
H48A
site directed mutagenesis
H52A
site directed mutagenesis, completely inactive
N56A
site directed mutagenesis, completely inactive
R141A
site directed mutagenesis, completely inactive
R222A
site directed mutagenesis, completely inactive
R82A
site directed mutagenesis, partially inactive
S78A
site directed mutagenesis, almost completely inactive
W44A
site directed mutagenesis, completely inactive
Y76A
site directed mutagenesis, completely inactive
D102A
-
completely inactive
H104A
-
the mutant shows 15.25% catalytic efficiency compared to the wild type enzyme
H38A
-
completely inactive
N108A
-
the mutant shows 50.83% catalytic efficiency compared to the wild type enzyme
P53A
-
completely inactive
Q49A
-
the mutant shows 1.15% catalytic efficiency compared to the wild type enzyme
Q64A
-
completely inactive
R109A
-
the mutant shows 0.88% catalytic efficiency compared to the wild type enzyme
R110A
-
completely inactive
R176A
-
the mutant shows 12.2% catalytic efficiency compared to the wild type enzyme
R8A
-
the mutant shows 12.26% catalytic efficiency compared to the wild type enzyme
R8A/R176A
-
the mutant shows 0.18% catalytic efficiency compared to the wild type enzyme
S9A
-
completely inactive
T11A
-
the mutant shows 97.81% catalytic efficiency compared to the wild type enzyme
D102A
-
completely inactive
-
H104A
-
the mutant shows 15.25% catalytic efficiency compared to the wild type enzyme
-
Q64A
-
completely inactive
-
R176A
-
the mutant shows 12.2% catalytic efficiency compared to the wild type enzyme
-
S9A
-
completely inactive
-