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5.2.1.2: maleylacetoacetate isomerase

This is an abbreviated version!
For detailed information about maleylacetoacetate isomerase, go to the full flat file.

Word Map on EC 5.2.1.2

Reaction

4-Maleylacetoacetate
=
4-Fumarylacetoacetate

Synonyms

AtGSTZ1, AtMAAI, glutathione S-transferase Zeta 1-1, glutathione S-transferase zeta-class 1, glutathione S-transferase zeta/maleylacetoacetate isomerase, glutathione transferase zeta, glutathione transferase zeta 1/maleylacetoacetate isomerase, Gstz1, GSTZ1-1, GSTz1/MAAI, GSTzeta/MAAI, Isomerase, maleylacetoacetate, MAAI, MAc-tI, maleylacetoacetate isomerase, Maleylacetoacetic isomerase, Maleylacetone cis-trans-isomerase, Maleylacetone isomerase, More

ECTree

     5 Isomerases
         5.2 cis-trans-Isomerases
             5.2.1 cis-trans Isomerases (only sub-subclass identified to date)
                5.2.1.2 maleylacetoacetate isomerase

Reference

Reference on EC 5.2.1.2 - maleylacetoacetate isomerase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Seltzer, S.
cis-trans Isomerization
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
6
381-406
1972
Vibrio sp.
-
Manually annotated by BRENDA team
Hagedorn, S.R.; Chapman, P.J.
Glutathione-independent maleylacetoacetate isomerase in gram-positive bacteria
J. Bacteriol.
163
803-805
1985
Corynebacterium sp., Moraxella sp., Nocardia globerula, Rhodococcus rhodnii, Pseudomonas alcaligenes, Nocardia globerula CL1
Manually annotated by BRENDA team
Feliu, A.L.; Smith, K.J.; Seltzer, S.
Unique, one-step, double isomerization (2E,4Z<-->2Z,4E) of 6-oxo-2,4-heptadienoic acid catalyzed by maleylacetone cis-trans isomerase
J. Am. Chem. Soc.
106
3046-3047
1984
Vibrio sp., Vibrio sp. 1
-
Manually annotated by BRENDA team
Lin, M.; Seltzer, S.
Maleylacetone cis-trans isomerase: formation of an N-ethylmaleimide-labeled enzyme only during the slow phase of the biphasic inhibition reaction
FEBS Lett.
124
169-172
1981
Vibrio sp.
-
Manually annotated by BRENDA team
Seltzer, S.; Lin, M.
Maleylacetone cis-trans-Isomerase. Mechanism of the interaction of coenzyme glutathione and substrate maleylacetone in the presence and absence of enzyme
J. Am. Chem. Soc.
101
3091-3097
1979
Vibrio sp.
-
Manually annotated by BRENDA team
Morrison, W.S.; Wong, G.; Seltzer, S.
Maleylacetone cis-trans-isomerase: affinity chromatography on glutathione-bound Sepharose. Two-substrate-binding sequence from inhibition patterns
Biochemistry
15
4228-4233
1976
Vibrio sp.
Manually annotated by BRENDA team
Seltzer, S.
Purification and properties of maleylacetone cis-trans isomerase from Vibrio 01
J. Biol. Chem.
248
215-222
1973
Vibrio sp.
Manually annotated by BRENDA team
Whitlow, K.J.; D'Iorio, A.; Mavrides, C.
Regulation of the enzymes of tyrosine catabolism in Tetrahymena pyriformis
Biochim. Biophys. Acta
264
440-449
1972
Tetrahymena pyriformis, Tetrahymena pyriformis W
Manually annotated by BRENDA team
Lack, L.
Enzymic cis-trans isomerization of maleylpyruvic acid
J. Biol. Chem.
236
2835-2840
1961
Pseudomonas sp.
Manually annotated by BRENDA team
Fernandez-Canon, J.M.; Penalva, M.A.
Characterization of a fungal maleylacetoacetate isomerase gene and identification of its human homologue
J. Biol. Chem.
273
329-337
1998
Aspergillus nidulans, Aspergillus nidulans (O43123), Homo sapiens, Homo sapiens (O43708)
Manually annotated by BRENDA team
Seltzer, S.; Hane, J.
Maleylacetate cis-trans isomerase: one-step double cis-trans isomerization of monomethyl muconate and the enzyme's probable role in benzene metabolism
Bioorg. Chem.
16
394-407
1988
Vibrio sp.
-
Manually annotated by BRENDA team
Angaw-Duguma, L.; Marecek, J.; Seltzer, S.
The synthesis and enzyme-catalyzed one-step cis-trans double isomerization of monomethyl 5-oxo-1,3-hexadien-1-ylphosphonate, an analogue of maleylacetone
Bioorg. Chem.
20
213-222
1992
Vibrio sp.
-
Manually annotated by BRENDA team
Seltzer, S.
Maleylacetoacetate cis-trans isomerase
Coenzymes and cofactors, Glutathione, Chem. Biochem. Med. Aspects Pt. A (Dolphin D, Poulson R, Avromonic O, eds. ) John Wiley & Sons, New York
3
733-751
1989
Mammalia, Vibrio sp.
-
Manually annotated by BRENDA team
Lee, H.E.; Seltzer, S.
cis-beta-Acetylacrylate is a substrate for maleylacetoacetate cis-trans isomerase. Mechanistic implications
Biochem. Int.
18
91-97
1989
Vibrio sp.
Manually annotated by BRENDA team
Board, P.G.; Taylor, M.C.; Coggan, M.; Parker, M.W.; Lantum, H.B.; Anders, M.W.
Clarification of the role of key active site residues of glutathione transferase zeta/maleylacetoacetate isomerase by a new spectrophotometric technique
Biochem. J.
374
731-737
2003
Homo sapiens
Manually annotated by BRENDA team
Polekhina, G.; Board, P.G.; Blackburn, A.C.; Parker, M.W.
Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity
Biochemistry
40
1567-1576
2001
Homo sapiens (O43708), Homo sapiens
Manually annotated by BRENDA team
Lim, C.E.; Matthaei, K.I.; Blackburn, A.C.; Davis, R.P.; Dahlstrom, J.E.; Koina, M.E.; Anders, M.W.; Board, P.G.
Mice deficient in glutathione transferase zeta/maleylacetoacetate isomerase exhibit a range of pathological changes and elevated expression of alpha, mu, and pi class glutathione transferases
Am. J. Pathol.
165
679-693
2004
Mus musculus
Manually annotated by BRENDA team
Qiang, L.; Farmer, S.R.
C/EBPalpha-dependent induction of glutathione S-transferase zeta/maleylacetoacetate isomerase (GSTzeta/MAAI) expression during the differentiation of mouse fibroblasts into adipocytes
Biochem. Biophys. Res. Commun.
340
845-851
2006
Mus musculus
Manually annotated by BRENDA team
Dixon, D.P.; Edwards, R.
Enzymes of tyrosine catabolism in Arabidopsis thaliana
Plant Sci.
171
360-366
2006
Arabidopsis thaliana (Q9ZVQ3), Arabidopsis thaliana
Manually annotated by BRENDA team
Theodoratos, A.; Tu, W.J.; Cappello, J.; Blackburn, A.C.; Matthaei, K.; Board, P.G.
Phenylalanine-induced leucopenia in genetic and dichloroacetic acid generated deficiency of glutathione transferase Zeta
Biochem. Pharmacol.
77
1358-1363
2009
Mus musculus
Manually annotated by BRENDA team
Shroads, A.L.; Langaee, T.; Coats, B.S.; Kurtz, T.L.; Bullock, J.R.; Weithorn, D.; Gong, Y.; Wagner, D.A.; Ostrov, D.A.; Johnson, J.A.; Stacpoole, P.W.
Human polymorphisms in the glutathione transferase zeta 1/maleylacetoacetate isomerase gene influence the toxicokinetics of dichloroacetate
J. Clin. Pharmacol.
52
837-849
2012
Homo sapiens
Manually annotated by BRENDA team
Boone, C.; Zhong, G.; Smeltz, M.; James, M.; McKenna, R.
Preliminary X-ray crystallographic analysis of glutathione transferase zeta 1 (GSTZ1a-1a)
Acta Crystallogr. Sect. F
70
187-189
2014
Homo sapiens (O43708)
Manually annotated by BRENDA team
Zolfaghari, N.
Competitive rational inhibitor design to 4-maleylaceto-acetate isomerase
Bioinformation
13
140-143
2017
Homo sapiens (O43708)
Manually annotated by BRENDA team
Shroads, A.L.; Coats, B.S.; Langaee, T.; Shuster, J.J.; Stacpoole, P.W.
Chloral hydrate, through biotransformation to dichloroacetate, inhibits maleylacetoacetate isomerase and tyrosine catabolism in humans
Drug Metab. Pers. Ther.
30
49-55
2015
Homo sapiens (O43708), Homo sapiens
Manually annotated by BRENDA team