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5.2.1.13: prolycopene isomerase

This is an abbreviated version!
For detailed information about prolycopene isomerase, go to the full flat file.

Word Map on EC 5.2.1.13

Reaction

7,9,7',9'-tetracis-lycopene
=
all-trans-lycopene

Synonyms

carotene cis-trans isomerase, carotenoid isomerase, CoCRTISO1-ORa, CoCRTISO1-ORb, CoCRTISO1Y, CoCRTISO2, CoCRTISO3, CoCRTISO4, CRTISO, LOC_Os11g36440, Mhz5, Mit3, ZEBRA LEAF 2, ZEBRA2, Zmcrtiso1

ECTree

     5 Isomerases
         5.2 cis-trans-Isomerases
             5.2.1 cis-trans Isomerases (only sub-subclass identified to date)
                5.2.1.13 prolycopene isomerase

Engineering

Engineering on EC 5.2.1.13 - prolycopene isomerase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
A412S
site-directed mutagenesis, the mutant shows substrate specificity like the wild-type enzyme
G450E
site-directed mutagenesis, the isozyme CoCRTISO1-ORb mutant is catalytically inactive
I370T
site-directed mutagenesis, the isozyme CoCRTISO1-ORa mutant is catalytically inactive
L581P
site-directed mutagenesis, the isozyme CoCRTISO1-ORa mutant is catalytically inactive
P584L
site-directed mutagenesis, the mutant shows substrate specificity like the wild-type enzyme
S412A
site-directed mutagenesis, the isozyme CoCRTISO1-ORb mutant is catalytically inactive