5.2.1.1: maleate isomerase
This is an abbreviated version!
For detailed information about maleate isomerase, go to the full flat file.
Word Map on EC 5.2.1.1
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5.2.1.1
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fumarate
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alcaligenes
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faecalis
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isomerization
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serratia
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racemase
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stearothermophilus
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marcescens
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synthesis
- 5.2.1.1
- fumarate
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alcaligenes
- faecalis
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isomerization
- serratia
- racemase
- stearothermophilus
- marcescens
- synthesis
Reaction
Synonyms
Isomerase, maleate, MaiA, maleate cis-trans isomerase, Pp-Iso
ECTree
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Natural Substrates Products on EC 5.2.1.1 - maleate isomerase
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REACTION DIAGRAM
Maleate
Fumarate
whole cells of recombinant Escherichia coli expressing enzyme mutant MaiR-D48 catalyze the isomerization of maleic acid to fumaric acid at 1 M substrate concentration
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r
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enzyme is induced by malonate favorably in a poor medium whereas it is repressed in a rich medium by carbon sources such as intermediates of the tricarboxylic acid cycle, catabolite repression is reversed by minimizing the functioning of the tricarboxylic acid cycle
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additional information
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malonate and ketomalonate are more effective than maleate in inducing isomerase synthesis
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additional information
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induction by tartronate, ketomalonate and ethylmalonate. Repression by oxalacetate or DL-malate
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additional information
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enzyme is induced by malonate favorably in a poor medium whereas it is repressed in a rich medium by carbon sources such as intermediates of the tricarboxylic acid cycle, catabolite repression is reversed by minimizing the functioning of the tricarboxylic acid cycle
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additional information
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induction by tartronate, ketomalonate and ethylmalonate. Repression by oxalacetate or DL-malate
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