5.1.99.6: NAD(P)H-hydrate epimerase
This is an abbreviated version!
For detailed information about NAD(P)H-hydrate epimerase, go to the full flat file.
Word Map on EC 5.1.99.6
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5.1.99.6
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nadphx
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dehydratase
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epimerization
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neurometabolic
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probands
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moonlighting
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coma
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febrile
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exome
-
edema
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cerebrospinal
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ataxia
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pyridoxal
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leukoencephalopathy
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medicine
- 5.1.99.6
-
nadphx
- dehydratase
-
epimerization
-
neurometabolic
- probands
-
moonlighting
-
coma
-
febrile
-
exome
-
edema
-
cerebrospinal
-
ataxia
- pyridoxal
- leukoencephalopathy
- medicine
Reaction
Synonyms
AIBP, APOA1BP, apolipoprotein A-1-binding protein, epimerase-PPOX, NAD(P)HX epimerase, NAXE, NnR, YjeF, YNL200C
ECTree
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Systematic Name
Systematic Name on EC 5.1.99.6 - NAD(P)H-hydrate epimerase
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(6R)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide 6-epimerase
The enzyme can use either (R)-NADH-hydrate or (R)-NADPH-hydrate as a substrate. Its physiological role is to convert the (R) forms to the (S) forms, which could then be restored to active dinucleotides by EC 4.2.1.93, ATP-dependent NAD(P)H-hydrate dehydratase.