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5.1.3.7: UDP-N-acetylglucosamine 4-epimerase

This is an abbreviated version!
For detailed information about UDP-N-acetylglucosamine 4-epimerase, go to the full flat file.

Word Map on EC 5.1.3.7

Reaction

UDP-N-acetyl-alpha-D-glucosamine
=
UDP-N-acetyl-alpha-D-galactosamine

Synonyms

Epimerase, uridine diphosphoacetylglucosamine, Galactowaldenase, GalE, galE-2, GalESp2, GNE, Gne epimerase, group 3 epimerase, KfoA, More, TM0509, TMGalE, UAE, UDP acetylglucosamine epimerase, UDP-galactose 4-epimerase, UDP-galactose-4-epimerase, UDP-GalNAc 4-epimerase, UDP-Glc(NAc) 4-epimerase, UDP-GlcNAc 4-epimerase, UDP-GlcNAc epimerase, UDP-GlcNAc/Glc 4-epimerase, UDP-hexose 4-epimerase, UDP-N-acetylglucosamine 4'-epimerase, UDP-N-acetylglucosamine 4-epimerase, UDP-N-acetylglucosamine-4'-epimerase, UDP-sugar 4-epimerase, UDPGlcNAc 4-epimerase, Uridine 5'-diphospho-N-acetylglucosamine-4-epimerase, Uridine diphosphate N-acetylglucosamine-4-epimerase, Uridine diphosphoacetylglucosamine epimerase, WbgU, WbPP

ECTree

     5 Isomerases
         5.1 Racemases and epimerases
             5.1.3 Acting on carbohydrates and derivatives
                5.1.3.7 UDP-N-acetylglucosamine 4-epimerase

Application

Application on EC 5.1.3.7 - UDP-N-acetylglucosamine 4-epimerase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
medicine
mutant deficient for gne shows increased surface hydrophobicity, produces deep alterations in the outer membrane architecture, and displays noticeable increases in the sensitivity to microcidal peptides, to eel and human sera, and to phagocytosis/opsonophagocytosis. Significant attenuation of virulence for eels and mice is observed with the mutant, which is correlated with the loss of the O-antigen lipopolysaccharide, while the capsule is maintained
synthesis