5.1.3.36: heparosan-glucuronate 5-epimerase

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For detailed information about heparosan-glucuronate 5-epimerase, go to the full flat file.

Reaction

Synonyms

HG-5epi

ECTree

     5 Isomerases

         5.1 Racemases and epimerases

             5.1.3 Acting on carbohydrates and derivatives

                5.1.3.36 heparosan-glucuronate 5-epimerase

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Results	in table
1	AA Sequence
1	Cloned(Commentary)
6	Inhibitors
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
1	Organism
1	pH Optimum
1	pH Range
1	Purification (Commentary)
1	Reaction
1	Reference
2	Substrates and Products (Substrate)
1	Subunits
1	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]

Systematic Name

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Systematic Name on EC 5.1.3.36 - heparosan-glucuronate 5-epimerase

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SYSTEMATIC NAME

IUBMB Comments

[heparosan]-D-glucuronate 5-epimerase

The enzyme, characterized from the giant African snail Achatina fulica, participates in the biosynthetic pathway of acharan sulfate. Unlike EC 5.1.3.17, heparosan-N-sulfate-glucuronate 5-epimerase, it shows no activity with D-glucuronate residues in heparosan-N-sulfate.