5.1.3.36: heparosan-glucuronate 5-epimerase

This is an abbreviated version!
For detailed information about heparosan-glucuronate 5-epimerase, go to the full flat file.

Reaction

Synonyms

HG-5epi

ECTree

     5 Isomerases

         5.1 Racemases and epimerases

             5.1.3 Acting on carbohydrates and derivatives

                5.1.3.36 heparosan-glucuronate 5-epimerase

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Results	in table
1	AA Sequence
1	Cloned(Commentary)
6	Inhibitors
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
1	Organism
1	pH Optimum
1	pH Range
1	Purification (Commentary)
1	Reaction
1	Reference
2	Substrates and Products (Substrate)
1	Subunits
1	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]

Substrates Products

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Substrates Products on EC 5.1.3.36 - heparosan-glucuronate 5-epimerase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

[heparosan]-D-glucuronate

[heparosan]-L-iduronate

2 entries

[heparosan]-D-glucuronate

[heparosan]-L-iduronate

Lissachatina fulica

A0A0C6EX43

it is suggested that the enzyme participates in the biosynthetic pathway of acharan sulfate

729809

-

-

?

[heparosan]-D-glucuronate

[heparosan]-L-iduronate

Lissachatina fulica

A0A0C6EX43

no activity with [heparosan]-N-sulfate D-glucuronate. At equilibrium of the epimerization, the proportion of IdoA in the reaction product reaches up to 30% of total hexuronic acid

729809

-

-

?