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5.1.3.27: dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase

This is an abbreviated version!
For detailed information about dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase, go to the full flat file.

Reaction

dTDP-4-dehydro-6-deoxy-alpha-D-glucose
=
dTDP-4-dehydro-6-deoxy-alpha-D-gulose

Synonyms

dTDP-4-keto-6-deoxy-D-glucose 3-epimerase, dTDP-4-keto-6-deoxyglucose 3-epimerase, dTDP-deoxyglucose 3-epimerase, GerF

ECTree

     5 Isomerases
         5.1 Racemases and epimerases
             5.1.3 Acting on carbohydrates and derivatives
                5.1.3.27 dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase

Systematic Name

Systematic Name on EC 5.1.3.27 - dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase

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SYSTEMATIC NAME
IUBMB Comments
dTDP-4-dehydro-6-deoxy-alpha-D-glucose 3-epimerase
The enzyme is involved in the biosynthetic pathway of dTDP-6-deoxy-alpha-D-allose, which is converted to mycinose after attachment to the aglycones of several macrolide antibiotics, including tylosin, chalcomycin, dihydrochalcomycin, and mycinamicin II.