5.1.3.19: chondroitin-glucuronate 5-epimerase
This is an abbreviated version!
For detailed information about chondroitin-glucuronate 5-epimerase, go to the full flat file.
Word Map on EC 5.1.3.19
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5.1.3.19
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iduronic
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glycosaminoglycans
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proteoglycans
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epimerization
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decorin
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d-glucuronic
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ehlers-danlos
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musculocontractural
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chst14
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4-o-sulfotransferase
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mceds
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idoa
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4-o-sulfated
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analysis
- 5.1.3.19
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iduronic
- glycosaminoglycans
- proteoglycans
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epimerization
- decorin
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d-glucuronic
- ehlers-danlos
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musculocontractural
- chst14
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4-o-sulfotransferase
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mceds
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idoa
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4-o-sulfated
- analysis
Reaction
Synonyms
Chondroitin D-glucuronosyl 5-epimerase, chondroitin-glucuronate C5-epimerase, dermatan sulfate epimerase, dermatan sulfate epimerase 1, dermatan sulfate epimerase 2, dermatan sulfate epimerase like, dermatan sulfate epimerase-2, dermatan sulfate epimerase-like a, dermatan sulfate epimerase-like b, Dermatan-sulfate 5-epimerase, DS epimerase 1, DS epimerase 2, DS-epi1, DS-epi2, DS-epimerase 1, DSE, DSEL, dsela, dselb, Epimerase, chondroitin glucuronate 5-, Polyglucuronate 5-epimerase, SART2
ECTree
5.1.3.19 chondroitin-glucuronate 5-epimeraseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 5.1.3.19 - chondroitin-glucuronate 5-epimerase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
D-glucuronate
L-iduronate
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in dermatan sulfate, iduronic acid residues are either clustered together in blocks or alternating with glucuronic acid, forming hybrid structures
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additional information
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most of the L-iduronic acid residues generated by the enzyme occur singly, although some formation of two or three consecutive L-iduronic acid residue containing disaccharide units is observed
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additional information
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dermatan sulfate and chondroitin sulfate are inactive as substrates, which indicates that epimerization takes place before sulfation
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additional information
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epimerization of D-glucuronosyl residues to L-iduronosyl during biosynthesis of dermatan sulfate
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additional information
?
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epimerization of D-glucuronosyl residues to L-iduronosyl during biosynthesis of dermatan sulfate
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