5.1.3.19: chondroitin-glucuronate 5-epimerase

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For detailed information about chondroitin-glucuronate 5-epimerase, go to the full flat file.

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Synonyms

Chondroitin D-glucuronosyl 5-epimerase, chondroitin-glucuronate C5-epimerase, dermatan sulfate epimerase, dermatan sulfate epimerase 1, dermatan sulfate epimerase 2, dermatan sulfate epimerase like, dermatan sulfate epimerase-2, dermatan sulfate epimerase-like a, dermatan sulfate epimerase-like b, Dermatan-sulfate 5-epimerase, DS epimerase 1, DS epimerase 2, DS-epi1, DS-epi2, DS-epimerase 1, DSE, DSEL, dsela, dselb, Epimerase, chondroitin glucuronate 5-, Polyglucuronate 5-epimerase, SART2

ECTree

     5 Isomerases

         5.1 Racemases and epimerases

             5.1.3 Acting on carbohydrates and derivatives

                5.1.3.19 chondroitin-glucuronate 5-epimerase

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Results	in table
1	Activating Compound
13	AA Sequence
1	Application
2	CAS Registry Number
9	Cloned(Commentary)
61	Disease/ Diagnostics
1	Expression
15	General Information
8	KM Value [mM]
5	Localization
3	Metals/Ions
1	Molecular Weight [Da]
12	Natural Substrates/ Products (Substrates)
21	Organism
5	Pathway
1	PDB ID
6	pH Optimum
2	Posttranslational Modification
9	Protein Variants
2	Purification (Commentary)
5	Reaction
1	Reaction Type
17	Reference
50	Source Tissue
28	Substrates and Products (Substrate)
1	Subunits
53	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]

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Cloned on EC 5.1.3.19 - chondroitin-glucuronate 5-epimerase

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

cloning and genomic structures of DS-epi1 and DS-epi2, transient functional overexpression of myc/His-tagged DS-epi1 and FLAG-tagged DS-epi2 in HEK-293 cell microsomes

Homo sapiens

-

704644

expression of wild-type and mutant enzymes in HEK-293 cells

Homo sapiens

Q9UL01

704498

functional recombinant enzyme expression in HEK-293 cells, all predicted N-glycans in DS-epi1 are present when the protein is expressed in the cells

Homo sapiens

-

747527

gene dse, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis

Danio rerio

B8A5U5, Q5RGL8

749050

gene dse, located on chromosome 5S, genetic structure, quantitative enzyme real-time PCR expression analysis

Xenopus laevis

A0A166W7U1, B1H189

749120

gene DSE, transient expression of wild-type and mutant enzymes in COS-7 cells

Homo sapiens

Q8IZU8, Q9UL01

727608

gene dsel, located on chromosome 5L, genetic structure, quantitative enzyme real-time PCR expression analysis

Xenopus laevis

A0A166W7U1, B1H189

749120

gene dsela, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis

Danio rerio

B8A5U5, Q5RGL8

749050

gene dselb, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis

Danio rerio

B8A5U5, Q5RGL8

749050