5.1.3.13: dTDP-4-dehydrorhamnose 3,5-epimerase

This is an abbreviated version!
For detailed information about dTDP-4-dehydrorhamnose 3,5-epimerase, go to the full flat file.

Reaction

Synonyms

3,5-epimerase, Agl13, bifunctional UDP-4-keto-6-deoxy-D-glucose epimerase/reductase, C14F11.6, deoxythymidine diphosphate-4-dehydrorhamnose 3,5-epimerase, deoxythymidine diphospho-4-keto-6-deoxyglucose 3,5-epimerase, DnmU, dTDP-4-dehydro-6-deoxy-glucose-3,5-epimerase, dTDP-4-dehydrorhamnose 3,5-epimerase, dTDP-4-keto-6-deoxy-D-hexulose 3,5-epimerase, dTDP-4-keto-6-deoxyglucose 3,5-epimerase, dTDP-4-keto-L-rhamnose 3,5-epimerase, dTDP-6-deoxy-D-xylo-4-hexulose 3',5'-epimerase, dTDP-L-rhamnose synthetase, Epimerase, thymidine diphospho-4-ketorhamnose 3,5-, NovW gene product, RfbC, RmbC, rml-3, RmlC, TDP-4-keto-6-deoxy-D-glucose 3,5-epimerase, TDP-4-keto-L-rhamnose-3,5-epimerase, TDP-4-ketorhamnose 3,5-epimerase, TDP-6-deoxy-D-xylo-4-hexopyranosid-4-ulose 3,5-epimerase, Thymidine diphospho-4-ketorhamnose 3,5-epimerase, UGER

ECTree

     5 Isomerases

         5.1 Racemases and epimerases

             5.1.3 Acting on carbohydrates and derivatives

                5.1.3.13 dTDP-4-dehydrorhamnose 3,5-epimerase

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Results	in table
29027	AA Sequence
6	Application
1	CAS Registry Number
12	Cloned(Commentary)
5	Cofactor
6	Crystallization (Commentary)
27	General Information
9	IC50 Value
10	Inhibitors
7	KM Value [mM]
1	Localization
2	Metals/Ions
8	Molecular Weight [Da]
21	Natural Substrates/ Products (Substrates)
221	Organism
11	Pathway
90	PDB ID
5	pH Optimum
6	Protein Variants
8	Purification (Commentary)
3	Reaction
5	Reaction Type
29	Reference
6	Source Tissue
32	Substrates and Products (Substrate)
6	Subunits
55	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Stability [°C]
6	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 5.1.3.13 - dTDP-4-dehydrorhamnose 3,5-epimerase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0004

1-(3-(5-allyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfonyl)-propyl)-1H-benzo[d]imidazol-2(3H)-one

Mycobacterium tuberculosis

P9WH11

pH 7.4, 25°C

702695

0.00012

1-(3-(5-allyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)propyl)-1H-benzo[d]imidazol-2(3H)-one

Mycobacterium tuberculosis

P9WH11

-

702695

0.02

1-(3-(5-allyl-8-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)propyl)-1H-benzo[d]imidazol-2(3H)-one

Mycobacterium tuberculosis

P9WH11

-

702695

0.0008

1-(3-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfonyl)-propyl)-1H-benzo[d]imidazol-2(3H)-one

Mycobacterium tuberculosis

P9WH11

pH 7.4, 25°C

702695

0.0002

1-(3-(5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)propyl)-1H-benzo[d]imidazol-2(3H)-one

Mycobacterium tuberculosis

P9WH11

pH 7.4, 25°C

702695

0.0005

1-(3-(5-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)propyl)-1H-benzo[d]imidazol-2(3H)-one

Mycobacterium tuberculosis

P9WH11

pH 7.4, 25°C

702695

0.0029

1-(3-(5-methylphenyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)propyl)-1H-benzo[d]imidazol-2(3H)-one

Mycobacterium tuberculosis

P9WH11

pH 7.4, 25°C

702695

0.00125

1-(3-(5-propyl-5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)propyl)-1H-benzo[d]imidazol-2(3H)-one

Mycobacterium tuberculosis

P9WH11

pH 7.4, 25°C

702695

0.0033

1-(3-(5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)propyl)-1H-benzo[d]imidazol-2(3H)-one

Mycobacterium tuberculosis

P9WH11

pH 7.4, 25°C

702695