5.1.1.9: arginine racemase

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For detailed information about arginine racemase, go to the full flat file.

Word Map on EC 5.1.1.9

5.1.1.9

racemization

transamination

dithiothreitol

graveolens

pyridoxal

Reaction

Synonyms

arginine racemase, ArgR, Racemase, arginine

ECTree

5 Isomerases

5.1 Racemases and epimerases

5.1.1 Acting on amino acids and derivatives

5.1.1.9 arginine racemase

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Results	in table
1	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
8	Cofactor
4	Crystallization (Commentary)
2	General Stability
8	Inhibitors
16	kcat/KM [mM/s]
20	KM Value [mM]
4	Localization
4	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
10	Organism
2	Pathway
6	pH Optimum
2	Protein Variants
5	Purification (Commentary)
1	Reaction
1	Reaction Type
10	Reference
4	Specific Activity [micromol/min/mg]
1	Storage Stability
41	Substrates and Products (Substrate)
2	Subunits
4	Synonyms
1	Systematic Name
16	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 5.1.1.9 - arginine racemase

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D-arginine

L-arginine

Pseudomonas aeruginosa

racemization of arginine is a two-step mechanism, intermediate is 2-keto-arginine, a first enzyme (DauA) catalyzes oxidative deamination of D-arginine into 2-ketoarginine and ammonia, and the second enzyme DauB is able to use 2-ketoarginine and ammonia as substrates and convert them into L-arginine in the presence of NADPH or NADH, DauA and DauB are coupled catabolic and anabolic dehydrogenases to perform D-to-L racemization of arginine, which serves as prerequisite of D-arginine utilization through L-arginine catabolic pathways

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