5.1.1.3: glutamate racemase

This is an abbreviated version!
For detailed information about glutamate racemase, go to the full flat file.

Word Map on EC 5.1.1.3

5.1.1.3

peptidoglycan

l-glutamate

cofactor-independent

drug development

pediococcus

poly-gamma-glutamate

pyrophilus

pentosaceus

fermenti

ciceri

stereoinversion

medicine

synthesis

Reaction

Synonyms

AAR, BAS0806, BAS4379, BcGR, BsGR, BsRacE, CBL/ALR, cystathionine beta-lyase, D-glutamate racemase, DapF, FnGR, GBAA_0847, GBAA_4717, GLR, GluR, glutamate racemase, glutamic acid racemases, GRL, HpMurI, MetC, More, MurI, RACE, RacE1, RacE2, Racemase, glutamate, Rv1338, TmCBL, wMelCBL

ECTree

5 Isomerases

5.1 Racemases and epimerases

5.1.1 Acting on amino acids and derivatives

5.1.1.3 glutamate racemase

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Results	in table
18	Activating Compound
34962	AA Sequence
17	Application
1	CAS Registry Number
43	Cloned(Commentary)
8	Cofactor
18	Crystallization (Commentary)
2	Expression
63	General Information
6	General Stability
126	IC50 Value
235	Inhibitors
34	kcat/KM [mM/s]
24	Ki Value [mM]
102	KM Value [mM]
1	Localization
1	Metals/Ions
33	Molecular Weight [Da]
55	Natural Substrates/ Products (Substrates)
144	Organism
8	Pathway
69	PDB ID
21	pH Optimum
7	pH Range
3	pH Stability
53	Protein Variants
36	Purification (Commentary)
15	Reaction
10	Reaction Type
120	Reference
2	Source Tissue
18	Specific Activity [micromol/min/mg]
4	Storage Stability
135	Substrates and Products (Substrate)
37	Subunits
104	Synonyms
1	Systematic Name
15	Temperature Optimum [°C]
5	Temperature Range [°C]
8	Temperature Stability [°C]
86	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 5.1.1.3 - glutamate racemase

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24.1

(R,S)-1-hydroxy-1-oxo-4-amino-4-carboxyphosphorinane

Enterococcus faecalis

pH and temperature not specified in the publication

727152

215

(R,S)-4-amino-4-carboxy-1,1-dioxotetrahydro-thiopyran

Enterococcus faecalis

pH and temperature not specified in the publication

727152

21.2

1,1-dioxo-tetrahydrothiopyran-4-one

Enterococcus faecalis

pH and temperature not specified in the publication

727152

0.0068

1-(3-(5-methylbenzo[d]oxazol-2-yl)phenyl)-3-(4-nitrophenyl)thiourea

Mycobacterium tuberculosis

P9WPW9

pH 8.0, 37°C, recombinant enzyme

747696

0.025

1-(3-(5-methylbenzo[d]oxazol-2-yl)phenyl)-3-(p-tolyl)thiourea

Mycobacterium tuberculosis

P9WPW9

above, pH 8.0, 37°C, recombinant enzyme

747696

0.0088

1-(3-(5-methylbenzo[d]oxazol-2-yl)phenyl)-3-phenylthiourea

Mycobacterium tuberculosis

P9WPW9

pH 8.0, 37°C, recombinant enzyme

747696

0.025

1-(3-(5-methylbenzo[d]oxazol-2-yl)phenyl)-3-phenylurea

Mycobacterium tuberculosis

P9WPW9

above, pH 8.0, 37°C, recombinant enzyme

747696

0.025

1-(3-(benzo[d]oxazol-2-yl)phenyl)-3-(4-chlorophenyl)thiourea

Mycobacterium tuberculosis

P9WPW9

above, pH 8.0, 37°C, recombinant enzyme

747696

0.0115

1-(3-(benzo[d]oxazol-2-yl)phenyl)-3-(4-chlorophenyl)urea

Mycobacterium tuberculosis

P9WPW9

pH 8.0, 37°C, recombinant enzyme

747696

0.0011

1-(3-(benzo[d]oxazol-2-yl)phenyl)-3-(4-fluorophenyl)thiourea

Mycobacterium tuberculosis

P9WPW9

pH 8.0, 37°C, recombinant enzyme

747696

0.00182

1-(3-(benzo[d]oxazol-2-yl)phenyl)-3-(4-fluorophenyl)urea

Mycobacterium tuberculosis

P9WPW9

pH 8.0, 37°C, recombinant enzyme

747696

0.025

1-(3-(benzo[d]oxazol-2-yl)phenyl)-3-(4-methoxyphenyl)urea

Mycobacterium tuberculosis

P9WPW9

above, pH 8.0, 37°C, recombinant enzyme

747696

0.0044

1-(3-(benzo[d]oxazol-2-yl)phenyl)-3-(4-nitrophenyl)thiourea

Mycobacterium tuberculosis

P9WPW9

pH 8.0, 37°C, recombinant enzyme

747696

0.025

1-(3-(benzo[d]oxazol-2-yl)phenyl)-3-(4-nitrophenyl)urea

Mycobacterium tuberculosis

P9WPW9

above, pH 8.0, 37°C, recombinant enzyme

747696

0.025

1-(3-(benzo[d]oxazol-2-yl)phenyl)-3-(p-tolyl)thiourea

Mycobacterium tuberculosis

P9WPW9

above, pH 8.0, 37°C, recombinant enzyme

747696

0.00835

1-(3-(benzo[d]oxazol-2-yl)phenyl)-3-(p-tolyl)urea

Mycobacterium tuberculosis

P9WPW9

pH 8.0, 37°C, recombinant enzyme

747696

0.0013

1-(3-(benzo[d]oxazol-2-yl)phenyl)-3-benzylthiourea

Mycobacterium tuberculosis

P9WPW9

pH 8.0, 37°C, recombinant enzyme

747696

0.025

1-(3-(benzo[d]oxazol-2-yl)phenyl)-3-benzylurea

Mycobacterium tuberculosis

P9WPW9

above, pH 8.0, 37°C, recombinant enzyme

747696

0.00712

1-(3-(benzo[d]oxazol-2-yl)phenyl)-3-isopropylurea

Mycobacterium tuberculosis

P9WPW9

pH 8.0, 37°C, recombinant enzyme

747696

0.025

1-(3-(benzo[d]oxazol-2-yl)phenyl)-3-phenylthiourea

Mycobacterium tuberculosis

P9WPW9

above, pH 8.0, 37°C, recombinant enzyme

747696

0.025

1-(3-(benzo[d]oxazol-2-yl)phenyl)-3-phenylurea

Mycobacterium tuberculosis

P9WPW9

above, pH 8.0, 37°C, recombinant enzyme

747696

0.025

1-(4-chlorophenyl)-3-(3-(5-methylbenzo[d]oxazol-2-yl)phenyl)thiourea

Mycobacterium tuberculosis

P9WPW9

above, pH 8.0, 37°C, recombinant enzyme

747696

0.025

1-(4-chlorophenyl)-3-(3-(5-methylbenzo[d]oxazol-2-yl)phenyl)urea

Mycobacterium tuberculosis

P9WPW9

above, pH 8.0, 37°C, recombinant enzyme

747696

0.0228

1-(4-fluorophenyl)-3-(3-(5-methylbenzo[d]oxazol-2-yl)phenyl)thiourea

Mycobacterium tuberculosis

P9WPW9

pH 8.0, 37°C, recombinant enzyme

747696

0.0085

1-(4-fluorophenyl)-3-(3-(5-methylbenzo[d]oxazol-2-yl)phenyl)urea

Mycobacterium tuberculosis

P9WPW9

pH 8.0, 37°C, recombinant enzyme

747696

0.025

1-(4-methoxyphenyl)-3-(3-(5-methylbenzo[d]oxazol-2-yl)phenyl)urea

Mycobacterium tuberculosis

P9WPW9

above, pH 8.0, 37°C, recombinant enzyme

747696

0.025

1-benzyl-3-(3-(5-methylbenzo[d]oxazol-2-yl)phenyl)thiourea

Mycobacterium tuberculosis

P9WPW9

above, pH 8.0, 37°C, recombinant enzyme

747696

47.7

1-hydroxyphosphinan-4-one 1-oxide

Enterococcus faecalis

pH and temperature not specified in the publication

727152

0.0009 - 0.0038

2-(butylsulfanyl)-8-(4-fluorobenzyl)-4-(methylamino)-5,8-dihydropteridine-6,7-dione

2 entries

0.0014 - 0.0025

2-(butylsulfanyl)-9-(2-methoxy-5-nitrobenzyl)-9H-purin-6-amine

2 entries

0.0022 - 0.0026

2-(butylsulfanyl)-9-(3-chloro-2,6-difluorobenzyl)-9H-purin-6-amine

2 entries

0.007 - 0.4

2-(butylsulfanyl)-9-(4-nitrophenyl)-9H-purin-6-amine

3 entries

105

2-amino-4-phosphonobutanoic acid

Enterococcus faecalis

pH and temperature not specified in the publication

727152

0.000026 - 0.0027

2-butoxy-9-(3-chloro-2,6-difluorobenzyl)-N-(pyridin-3-ylmethyl)-9H-purin-6-amine

3 entries

0.000033

2-[(5-chloro-1-methyl-1H-indol-3-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-3-[1-methyl-4-(methylsulfonyl)-1H-pyrrol-2-yl]-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

Q9ZLT0

691296

0.000069

2-[(6-chloroquinolin-4-yl)methyl]-5,7-bis(cyclopropylmethyl)-3-(1-methyl-1H-imidazol-5-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000079

2-[(6-chloroquinolin-4-yl)methyl]-5-cyclopropyl-7-(cyclopropylmethyl)-3-(1-methyl-1H-imidazol-5-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00017

2-[(6-chloroquinolin-4-yl)methyl]-5-methyl-3-(1-methyl-1H-imidazol-5-yl)-7-(2-methylpropyl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00026

2-[(6-chloroquinolin-4-yl)methyl]-5-methyl-7-(2-methylpropyl)-3-(1-methyl-1H-pyrrol-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00046

2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-3-(1-methyl-1H-imidazol-5-yl)-5-(pent-4-yn-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000056

2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-3-(1-methyl-1H-imidazol-5-yl)-5-(prop-2-en-1-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000024

2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-3-(1-methyl-1H-imidazol-5-yl)-5-(prop-2-yn-1-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00022

2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-3-(1-methyl-1H-imidazol-5-yl)-5-(propan-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00017

2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-3-(1-methyl-1H-imidazol-5-yl)-5-[4-(morpholin-4-yl)but-2-yn-1-yl]-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000054

2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-(3-hydroxyprop-2-yn-1-yl)-3-(1-methyl-1H-imidazol-5-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000072

2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-ethyl-3-(1-methyl-1H-imidazol-5-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00081

2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-3-(1-methyl-1H-1,2,4-triazol-5-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000041

2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-3-(1-methyl-1H-imidazol-5-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.0009

2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-3-(4-methyl-1H-imidazol-5-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00022

2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-3-(4-methyl-1H-pyrazol-3-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00023

2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-3-(4-methyl-4H-1,2,4-triazol-3-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000034

2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-3-[1-methyl-4-(methylsulfonyl)-1H-pyrrol-2-yl]-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

2 entries

0.00015

2-[2-[(6-chloroquinolin-4-yl)methyl]-5,7-bis(cyclopropylmethyl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-imidazole-4-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00025

2-[2-[(6-chloroquinolin-4-yl)methyl]-5-cyclopropyl-7-(cyclopropylmethyl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-imidazole-4-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00025

2-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-4,6-dioxo-5-(prop-2-en-1-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-imidazole-4-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000089

2-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-4,6-dioxo-5-(prop-2-yn-1-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-imidazole-4-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00018

2-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-ethyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-imidazole-4-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000087

2-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-imidazole-4-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00074

3-(2-amino-4-methyl-1,3-thiazol-5-yl)-2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00028

3-(2-amino-5-methyl-1,3-thiazol-4-yl)-2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.0028

3-(3-chlorothiophen-2-yl)-5-(furan-2-yl)-N-methyl-3H-pyrido[2,3-e][1,4]diazepin-2-amine

Helicobacter pylori

Q9ZLT0

691326

0.000039

3-(4-acetyl-1-methyl-1H-pyrrol-2-yl)-2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.007

3-(5-methylbenzo[d]oxazol-2-yl)aniline

Mycobacterium tuberculosis

P9WPW9

pH 8.0, 37°C, recombinant enzyme

747696

0.025

3-(benzo[d]oxazol-2-yl)aniline

Mycobacterium tuberculosis

P9WPW9

above, pH 8.0, 37°C, recombinant enzyme

747696

2.9

3-sulfobenzoic acid

Bacillus subtilis

Q6L876

structural analogue of dipicolinate dianion

704192

0.0015 - 0.0031

4-amino-2-(butylsulfanyl)-8-(2,6-difluorobenzyl)-5,8-dihydropteridine-6,7-dione

2 entries

0.00065 - 0.0015

4-amino-2-(butylsulfanyl)-8-(3,4-dichlorobenzyl)-5,8-dihydropteridine-6,7-dione

2 entries

0.0011 - 0.0035

4-amino-2-(butylsulfanyl)-8-(4-fluorobenzyl)-5,8-dihydropteridine-6,7-dione

2 entries

0.0076 - 0.021

4-amino-8-benzyl-2-(benzylsulfanyl)-5,8-dihydropteridine-6,7-dione

2 entries

0.0024 - 0.0064

4-amino-8-benzyl-2-(butylsulfanyl)-5,8-dihydropteridine-6,7-dione

2 entries

0.0019 - 0.052

4-amino-8-benzyl-2-(cyclopentylsulfanyl)-5,8-dihydropteridine-6,7-dione

2 entries

0.00022

4-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-5-methylfuran-2-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000063

5-(but-2-yn-1-yl)-2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-3-(1-methyl-1H-imidazol-5-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.002

5-(furan-2-yl)-N-methyl-3-(thiophen-2-yl)-3H-pyrido[2,3-e][1,4]diazepin-2-amine

Helicobacter pylori

Q9ZLT0

691326

0.0014

5-methyl-7-(2-methylpropyl)-2-(naphthalen-1-ylmethyl)-3-(pyridin-4-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000062

5-[2-[(6-chloroquinolin-4-yl)methyl]-5,7-bis(cyclopropylmethyl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000055

5-[2-[(6-chloroquinolin-4-yl)methyl]-5-(cyanomethyl)-7-(cyclopropylmethyl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00008

5-[2-[(6-chloroquinolin-4-yl)methyl]-5-cyclopropyl-7-(cyclopropylmethyl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000086

5-[2-[(6-chloroquinolin-4-yl)methyl]-5-methyl-7-(2-methylpropyl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00007

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-4,6-dioxo-5-(prop-2-en-1-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000028

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-4,6-dioxo-5-(prop-2-yn-1-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00024

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-4,6-dioxo-5-(propan-2-yl)-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00067

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-4,6-dioxo-5-[2-(1H-1,2,3-triazol-1-yl)ethyl]-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00047

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-4,6-dioxo-5-[2-(1H-pyrazol-1-yl)ethyl]-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000013

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-4,6-dioxo-5-[4-(1H-1,2,4-triazol-1-yl)but-2-yn-1-yl]-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00012

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-4,6-dioxo-5-[4-(1H-pyrazol-1-yl)but-2-yn-1-yl]-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000088

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-(2-hydroxyethyl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000057

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-(4-hydroxybut-2-yn-1-yl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00007

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-ethyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000026

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00006

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-4-methylfuran-2-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00026

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-[4-(1H-imidazol-1-yl)but-2-yn-1-yl]-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000051

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-[4-(morpholin-4-yl)but-2-yn-1-yl]-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.000016

5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-[5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl]-1H-pyrrole-3-sulfonamide

Helicobacter pylori

Q9ZLT0

691296

0.000074

5-[5-(but-2-yn-1-yl)-2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.00016

5-[5-(but-3-yn-2-yl)-2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-pyrrole-3-carbonitrile

Helicobacter pylori

pH and temperature not specified in the publication

727144

0.0043 - 0.0044

9-(2,6-difluoro-3-methylbenzyl)-2-[(1,1,1,2,2-pentafluoropentan-3-yl)oxy]-9H-purin-6-amine

2 entries

0.0353

bis(2,4-bis (trichloromethyl)-1,3,5-triazapentadienato)-Zn(II) complex

Burkholderia cenocepacia

recombinant enzyme, pH 8.0, 37°C

749098

60.4

bis(2-carboxyethyl)-phosphinic acid

Enterococcus faecalis

pH and temperature not specified in the publication

727152

0.15

dipicolinic acid

Burkholderia cenocepacia

recombinant enzyme, pH 8.0, 37°C

749098

0.0044 - 0.361

exiguaquinol

2 entries

0.0017

N,8-dimethyl-5-phenyl-3-(thiophen-2-yl)-3H-pyrido[2,3-e][1,4]diazepin-2-amine

Helicobacter pylori

Q9ZLT0

691326

0.00625

N-benzyl-N'-[3-(5-methyl-1,3-benzoxazol-2-yl)phenyl]urea

Mycobacterium tuberculosis

P9WPW9

pH 8.0, 37°C, recombinant enzyme

747696

0.0007

N-methyl-3,5-di(thiophen-2-yl)-3H-pyrido[2,3-e][1,4]diazepin-2-amine

Helicobacter pylori

Q9ZLT0

691326

0.0006

N-methyl-5-(1H-pyrrol-3-yl)-3-(thiophen-2-yl)-3H-pyrido[2,3-e][1,4]diazepin-2-amine

Helicobacter pylori

Q9ZLT0

691326

0.0022

N-methyl-5-phenyl-3-(thiophen-2-yl)-3H-pyrido[2,3-e][1,4]diazepin-2-amine

Helicobacter pylori

Q9ZLT0

691326

0.0014 - 0.4

pyrazolopyrimidinedione analogue

3 entries

0.01

tris(2,4-bis(trichloromethyl)-1,3,5-triazapentadienate)-Mn(III) complex

Burkholderia cenocepacia

recombinant enzyme, pH 8.0, 37°C

749098