5.1.1.22: 4-hydroxyproline betaine 2-epimerase

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For detailed information about 4-hydroxyproline betaine 2-epimerase, go to the full flat file.

Reaction

Synonyms

(4R)-4-hydroxyproline betaine 2-epimerase, hpbD, Hyp-B 2-epimerase

ECTree

5 Isomerases

5.1 Racemases and epimerases

5.1.1 Acting on amino acids and derivatives

5.1.1.22 4-hydroxyproline betaine 2-epimerase

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Results	in table
3	AA Sequence
1	Cloned(Commentary)
2	Crystallization (Commentary)
2	kcat/KM [mM/s]
2	KM Value [mM]
6	Natural Substrates/ Products (Substrates)
4	Organism
1	Pathway
2	Reaction
4	Reference
6	Substrates and Products (Substrate)
7	Synonyms
1	Systematic Name
2	Turnover Number [1/s]

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Reference on EC 5.1.1.22 - 4-hydroxyproline betaine 2-epimerase

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740940

Kumar, R.; Zhao, S.; Vetting, M.W.; Wood, B.M.; Sakai, A.; Cho, K.; Solbiati, J.; Almo, S.C.; Sweedler, J.V.; Jacobson, M.P.; Gerlt, J.A.; Cronan, J.E.

Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine

mBio

e00933

2014

Paracoccus denitrificans (A1B198), Paracoccus denitrificans Pd 1222 (A1B198)

24520058

741061

Zhao, S.; Kumar, R.; Sakai, A.; Vetting, M.W.; Wood, B.M.; Brown, S.; Bonanno, J.B.; Hillerich, B.S.; Seidel, R.D.; Babbitt, P.C.; Almo, S.C.; Sweedler, J.V.; Gerlt, J.A.; Cronan, J.E.; Jacobson, M.P.

Discovery of new enzymes and metabolic pathways by using structure and genome context

Nature

502

698-702

2013

Salipiger bermudensis (Q0FPQ4), Salipiger bermudensis JCM 13377 (Q0FPQ4)

24056934