5.1.1.21: isoleucine 2-epimerase

This is an abbreviated version!
For detailed information about isoleucine 2-epimerase, go to the full flat file.

Word Map on EC 5.1.1.21

5.1.1.21

buchneri

racemization

lactobacillus

epimerization

5'-phosphate

pyridoxal

nonpolar

d-leucine

diaminopimelate

two-base

l-isoleucine

d-valine

Reaction

Synonyms

amino acid racemase, BCAA racemase, branched-chain amino-acid racemase, D-amino acid racemase, DAAR1, ILEP, isoleucine 2-epimerase, phenazine biosynthesis PhzC/PhzF family protein, PLP-dependent fold-type I isoleucine 2-epimerase, PLP-independent racemase

ECTree

5 Isomerases

5.1 Racemases and epimerases

5.1.1 Acting on amino acids and derivatives

5.1.1.21 isoleucine 2-epimerase

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Results	in table
37	AA Sequence
4	Cloned(Commentary)
5	Cofactor
2	Crystallization (Commentary)
10	General Information
2	Inhibitors
11	kcat/KM [mM/s]
11	KM Value [mM]
3	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
10	Organism
16	PDB ID
3	pH Optimum
1	pH Stability
4	Protein Variants
5	Purification (Commentary)
4	Reaction
8	Reference
1	Source Tissue
17	Specific Activity [micromol/min/mg]
1	Storage Stability
35	Substrates and Products (Substrate)
4	Subunits
17	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Stability [°C]
11	Turnover Number [1/s]

Reference

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Reference on EC 5.1.1.21 - isoleucine 2-epimerase

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729935

Mutaguchi, Y.; Ohmori, T.; Wakamatsu, T.; Doi, K.; Ohshima, T.

Identification, purification, and characterization of a novel amino acid racemase, isoleucine 2-epimerase, from Lactobacillus species

J. Bacteriol.

195

5207-5215

2013

Lentilactobacillus otakiensis, Lentilactobacillus buchneri (M1GRN3), Lentilactobacillus buchneri, Lentilactobacillus otakiensis JCM 15040, Lentilactobacillus buchneri JCM 1115 (M1GRN3)

24039265

746630

Hayashi, J.; Mutaguchi, Y.; Minemura, Y.; Nakagawa, N.; Yoneda, K.; Ohmori, T.; Ohshima, T.; Sakuraba, H.

Crystal structure of the novel amino-acid racemase isoleucine 2-epimerase from Lactobacillus buchneri

Acta Crystallogr. Sect. D

428-437

2017

Lentilactobacillus buchneri (M1GRN3), Lentilactobacillus buchneri

28471367

747208

Awad, R.; Gans, P.; Reiser, J.B.

Structural insights into the substrate recognition and reaction specificity of the PLP-dependent fold-type I isoleucine 2-epimerase from Lactobacillus buchneri

Biochimie

137

165-173

2017

Lentilactobacillus buchneri (M1GRN3), Lentilactobacillus buchneri, Lentilactobacillus buchneri JCM 1115 (M1GRN3)

28344038

749170

Strauch, R.C.; Svedin, E.; Dilkes, B.; Chapple, C.; Li, X.

Discovery of a novel amino acid racemase through exploration of natural variation in Arabidopsis thaliana

Proc. Natl. Acad. Sci. USA

112

11726-11731

2015

Arabidopsis thaliana (Q66GM9), Arabidopsis thaliana

26324904