5.1.1.17: isopenicillin-N epimerase
This is an abbreviated version!
For detailed information about isopenicillin-N epimerase, go to the full flat file.
Word Map on EC 5.1.1.17
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5.1.1.17
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cephalosporin
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acremonium
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chrysogenum
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beta-lactam
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clavuligerus
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epimerization
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deacetoxycephalosporin
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cefef
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pyridoxal
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pcbab
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deacetylcephalosporin
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cephamycins
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expandase
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acyltransferase
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pende
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untransformed
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alpha-aminoadipic
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lactamdurans
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daocs
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biotechnology
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synthesis
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medicine
- 5.1.1.17
- cephalosporin
- acremonium
- chrysogenum
- beta-lactam
- clavuligerus
-
epimerization
-
deacetoxycephalosporin
- cefef
- pyridoxal
-
pcbab
-
deacetylcephalosporin
-
cephamycins
-
expandase
- acyltransferase
-
pende
-
untransformed
-
alpha-aminoadipic
- lactamdurans
- daocs
- biotechnology
- synthesis
- medicine
Reaction
Synonyms
cefD2, IPN epimerase, isopenecillin N-CoA epimerase, isopenicillin N epimerase, isopenicillin N-CoA epimerase, PenN epimerase
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Natural Substrates Products
Natural Substrates Products on EC 5.1.1.17 - isopenicillin-N epimerase
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REACTION DIAGRAM
isopenicillin N
penicillin N
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part of the cephalosporin pathway
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?
isopenicillin N
penicillin N
Acremonium chrysogenum C10 / ATCC 48272
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part of the cephalosporin pathway
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?
isopenicillin N
penicillin N
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enzyme epimerizes the side chain of alpha-aminoadipic acid in isopenicillin N from the L- to the D-configuration, this is an important step since the next enzyme in the pathway, DAOCS, is unable to use isopenicillin N as substrate, in spite of the apparent minor structural difference between the two molecules
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r
isopenicillin N
penicillin N
-
part of the cephalosporin pathway
-
?
isopenicillin N
penicillin N
-
part of the cephalosporin pathway
-
r