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5.1.1.15: 2-aminohexano-6-lactam racemase

This is an abbreviated version!
For detailed information about 2-aminohexano-6-lactam racemase, go to the full flat file.

Word Map on EC 5.1.1.15

Reaction

(S)-2-aminohexano-6-lactam
=
(R)-2-aminohexano-6-lactam

Synonyms

ACL racemase, ACLR, alpha-Amino-delta-valerolactam racemase, alpha-Amino-epsilon-caprolactam racemase, Aminocaprolactam racemase, moe, More, Racemase, alpha-amino-epsilon-caprolactam, Racemase, alpha-amino-epsilon-caprolactam (Achromobacter obae reduced), SMc02413

ECTree

     5 Isomerases
         5.1 Racemases and epimerases
             5.1.1 Acting on amino acids and derivatives
                5.1.1.15 2-aminohexano-6-lactam racemase

Substrates Products

Substrates Products on EC 5.1.1.15 - 2-aminohexano-6-lactam racemase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
D-2-amino-delta-valerolactam
L-2-amino-delta-valerolactam
show the reaction diagram
-
best substrate
-
-
r
D-2-amino-omega-octalactam
L-2-amino-omega-octalactam
show the reaction diagram
-
1.78% activity compared to D-2-aminohexano-6-lactam
-
-
r
D-2-aminobutyric acid amide
L-2-aminobutyric acid amide
show the reaction diagram
-
0.19% activity compared to D-2-aminohexano-6-lactam
-
-
r
D-2-aminohexano-6-lactam
L-2-aminohexano-6-lactam
show the reaction diagram
D-Ala
L-Ala
show the reaction diagram
-
-
-
-
r
D-alanine amide
L-alanine amide
show the reaction diagram
-
2.12% activity compared to D-2-aminohexano-6-lactam
-
-
r
D-alpha-amino-beta-caprolactam
DL-alpha-amino-beta-caprolactam
show the reaction diagram
-
-
-
-
?
L-2-amino-delta-valerolactam
D-2-amino-delta-valerolactam
show the reaction diagram
-
17.2% activity compared to D-2-aminohexano-6-lactam
-
-
r
L-2-amino-omega-octalactam
D-2-amino-omega-octalactam
show the reaction diagram
-
1.41% activity compared to D-2-aminohexano-6-lactam
-
-
r
L-2-aminobutyric acid amide
D-2-aminobutyric acid amide
show the reaction diagram
L-2-aminohexano-6-lactam
D-2-aminohexano-6-lactam
show the reaction diagram
L-alanine amide
D-alanine amide
show the reaction diagram
L-alpha-Amino-beta-thio-epsilon-caprolactam
D-alpha-Amino-beta-thio-epsilon-caprolactam
show the reaction diagram
-
racemized more than 3times faster and binds about 4fold stronger to the enzyme than L-alpha-amino-epsilon-caprolactam
-
-
?
L-alpha-Amino-delta-valerolactam
D-alpha-Amino-delta-valerolactam
show the reaction diagram
-
-
-
?
L-alpha-Amino-epsilon-caprolactam
D-alpha-Amino-epsilon-caprolactam
show the reaction diagram
L-leucine amide
D-leucine amide
show the reaction diagram
L-methionine amide
D-methionine amide
show the reaction diagram
L-phenylalanine amide
D-phenylalanine amide
show the reaction diagram
L-phenylglycine amide
D-phenylglycine amide
show the reaction diagram
L-serine amide
D-serine amide
show the reaction diagram
L-valine amide
D-valine amide
show the reaction diagram
additional information
?
-