5.1.1.1: alanine racemase
This is an abbreviated version!
For detailed information about alanine racemase, go to the full flat file.
Word Map on EC 5.1.1.1
-
5.1.1.1
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pyridoxal
-
5'-phosphate
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peptidoglycan
-
racemization
-
d-cycloserine
-
stearothermophilus
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plp-dependent
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d-amino
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aldimine
-
d-alanyl-d-alanine
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exosporium
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pyridoxal-5'-phosphate-dependent
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drug development
-
5'-phosphate-dependent
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d-alanine:d-alanine
-
medicine
-
biotechnology
-
pharmacology
- 5.1.1.1
- pyridoxal
- 5'-phosphate
- peptidoglycan
-
racemization
- d-cycloserine
- stearothermophilus
-
plp-dependent
-
d-amino
-
aldimine
- d-alanyl-d-alanine
- exosporium
-
pyridoxal-5'-phosphate-dependent
- drug development
-
5'-phosphate-dependent
-
d-alanine:d-alanine
- medicine
- biotechnology
- pharmacology
Reaction
Synonyms
1SFT, AAR, alanine racemase, AlaR, ALR, alr-2, ALR1, ALR2, Alr2 racemase, AlrA, AlrAba, AlrBax, AlrMtb, alrTt, ARL, BA0252, BAS0238, CBL/ALR, CdAlr, cystathionine beta-lyase, D-alanine racemase, DadB, DadX, dadXOF4, dal1, EcAlr, EcCBL, EfAlaR, L-Alanine racemase, L-Alanine:D-alanine racemase, MBalr1, MBAlr2, MetC, More, MurI, OEOE_1641, PDB, Racemase, alanine, tAlaRac, TmCBL, wMelCBL
ECTree
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Turnover Number
Turnover Number on EC 5.1.1.1 - alanine racemase
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2.5
D-Lysine
pH 8.0, 30°C, recombinant mutant I222T/Y354W
4.17
L-lysine
pH 8.0, 30°C, recombinant mutant I222T/Y354W
0.333
D-alanine
+/-0.033, Alr D164K, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
1.317
D-alanine
+/-0.100, Alr E165K, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
4
D-alanine
+/-0.417, Alr E165A, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
4.466
D-alanine
+/-0.200, Alr D164A, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
5.267
D-alanine
+/-0.333, Alr P219A, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
5.783
D-alanine
+/-0.483, Alr wildtype, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
6.35
D-alanine
+/-0.333, Alr E221K, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
6.817
D-alanine
+/-0.650, Alr E221A, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
7.617
D-alanine
+/-0.750, Alr E221P, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
19.25
D-alanine
pH 8.5, temperature not specified in the publication, recombinant wild-type enzyme
32.5
D-alanine
pH 10.0, 65°C, recombinant mutant S173D
96.9
D-alanine
pH 10.0, 65°C, recombinant wild-type enzyme
133.1
D-alanine
pH 10.0, 65°C, recombinant mutant S173D/Q360Y
225
D-alanine
pH 10.0, 65°C, recombinant mutant Q360I
251.2
D-alanine
pH 10.0, 65°C, recombinant mutant Q360Y
633
D-alanine
pH 8.0, 30°C, recombinant mutant I222T/Y354W
633.5
D-alanine
pH 10.0, 65°C, recombinant mutant Q360W
1017
D-alanine
pH 8.0, 30°C, recombinant wild-type enzyme
1298.4
D-alanine
pH 8.5, temperature not specified in the publication, recombinant mutant K271T
0.0024
recombinant His-tagged enzyme, pH 8.0, 70°C, bicine buffer
0.0065
L-alanine
recombinant His-tagged enzyme, pH 8.0, 37°C, bicine buffer
0.022
L-alanine
recombinant His-tagged enzyme, pH 8.0, 37°C, Tris buffer
0.15
L-alanine
recombinant MBP-tagged enzyme, pH 8.0, 37°C
2.8
L-alanine
+/-0.250, Alr D164K, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
16.72
L-alanine
+/-0.850, Alr E165K, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
22.47
L-alanine
+/-2.667, Alr E165A, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
34.7
L-alanine
pH 10.0, 65°C, recombinant mutant S173D
41.82
L-alanine
+/-2.600, Alr D164A, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
51.77
L-alanine
+/-6.067, Alr P219A, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
53.98
L-alanine
+/-3.217, Alr wildtype, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
59.3
L-alanine
pH 8.5, temperature not specified in the publication, recombinant wild-type enzyme
67.07
L-alanine
+/-7.633, Alr E221P, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
68.23
L-alanine
+/-7.550, Alr E221K, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
70.92
L-alanine
+/-2.333, Alr E221A, 30°C, pH 8.0, spectrophotometrically measured at 340 nm
212.4
L-alanine
pH 10.0, 65°C, recombinant wild-type enzyme
246.5
L-alanine
pH 10.0, 65°C, recombinant mutant S173D/Q360Y
286.6
L-alanine
pH 10.0, 65°C, recombinant mutant Q360I
431.5
L-alanine
pH 10.0, 65°C, recombinant mutant Q360Y
612.4
L-alanine
pH 10.0, 65°C, recombinant mutant Q360W
1133
L-alanine
pH 8.0, 30°C, recombinant mutant I222T/Y354W
1533
L-alanine
pH 8.0, 30°C, recombinant wild-type enzyme
3275.5
L-alanine
pH 8.5, temperature not specified in the publication, recombinant mutant K271T