5.1.1.1: alanine racemase
This is an abbreviated version!
For detailed information about alanine racemase, go to the full flat file.
Word Map on EC 5.1.1.1
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5.1.1.1
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pyridoxal
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5'-phosphate
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peptidoglycan
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racemization
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d-cycloserine
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stearothermophilus
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plp-dependent
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d-amino
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aldimine
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d-alanyl-d-alanine
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exosporium
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pyridoxal-5'-phosphate-dependent
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drug development
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5'-phosphate-dependent
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d-alanine:d-alanine
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medicine
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biotechnology
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pharmacology
- 5.1.1.1
- pyridoxal
- 5'-phosphate
- peptidoglycan
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racemization
- d-cycloserine
- stearothermophilus
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plp-dependent
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d-amino
-
aldimine
- d-alanyl-d-alanine
- exosporium
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pyridoxal-5'-phosphate-dependent
- drug development
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5'-phosphate-dependent
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d-alanine:d-alanine
- medicine
- biotechnology
- pharmacology
Reaction
Synonyms
1SFT, AAR, alanine racemase, AlaR, ALR, alr-2, ALR1, ALR2, Alr2 racemase, AlrA, AlrAba, AlrBax, AlrMtb, alrTt, ARL, BA0252, BAS0238, CBL/ALR, CdAlr, cystathionine beta-lyase, D-alanine racemase, DadB, DadX, dadXOF4, dal1, EcAlr, EcCBL, EfAlaR, L-Alanine racemase, L-Alanine:D-alanine racemase, MBalr1, MBAlr2, MetC, More, MurI, OEOE_1641, PDB, Racemase, alanine, tAlaRac, TmCBL, wMelCBL
ECTree
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Application
Application on EC 5.1.1.1 - alanine racemase
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biotechnology
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use of enzyme gene as a promoter-screening tool for identification of conditional promoters in Lactobacillus plantarum. Screen for clones capable of complementing the D-alanine auxotroph phenotype of enzyme deletion mutant in media containing enzyme inhibitor D-cycloserine
drug development
medicine
pharmacology
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the enzyme is an attractive target for antimicrobial drug development
drug development
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Alr is a target for the development of antibacterial drugs
drug development
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Alr is a target for the development of antibacterial drugs
drug development
Alr is a target for the development of antibacterial drugs
drug development
Alr is a target for the development of antibacterial drugs
drug development
the enzyme is a potential target for development of antibiotic compounds
drug development
the enzyme is a target for antibiotic drug development, especially the dimer interface a potential target for structure-aided drug design
drug development
Alkalihalophilus pseudofirmus
the enzyme is an attractive target for designing antibacterial drugs
drug development
Alkalihalophilus pseudofirmus OF4
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the enzyme is an attractive target for designing antibacterial drugs
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drug development
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the enzyme is a potential target for development of antibiotic compounds
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drug development
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the enzyme is an attractive target for antimicrobial drug development
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drug development
Pseudomonas aeruginosa ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1
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Alr is a target for the development of antibacterial drugs
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the requirement for D-Ala as a necessary component of the bacterial cell wall makes the enzyme a logical target for the development of novel antibiotics
medicine
since it is absent in humans, this enzyme is an attractive target for the development of drugs against Streptococcus pneumoniae and other bacterial pathogens
medicine
Alr might be a potential target for the prevention and treatment of caries
medicine
Streptococcus mutans serotype c ATCC 700610 / UA159
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Alr might be a potential target for the prevention and treatment of caries
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potential candidate for the development of a recombinant vaccine
pharmacology
Alr of Mycobacterium tuberculosis is a valid drug target and inhibition of Alr alone results in loss of viability in vitro and in vivo
pharmacology
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Alr of Mycobacterium tuberculosis is a valid drug target and inhibition of Alr alone results in loss of viability in vitro and in vivo
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