4.99.1.8: heme ligase

This is an abbreviated version!
For detailed information about heme ligase, go to the full flat file.

Word Map on EC 4.99.1.8

4.99.1.8

plasmodium

malaria

hemozoin

falciparum

hemoglobin

antimalarial

vacuole

chloroquine

detoxify

medicine

artemisinins

reductase-thymidylate

byproduct

dihydrofolate

heme-binding

polymerization

yoelii

analysis

Reaction

2 ferriprotoporphyrin IX =

Synonyms

alpha-HDP, HDP, heme detoxification protein, heme-detoxification protein

ECTree

4 Lyases

4.99 Other lyases

4.99.1 Sole sub-subclass for lyases that do not belong in the other subclasses

4.99.1.8 heme ligase

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Results	in table
3	AA Sequence
4	Application
5	Cloned(Commentary)
3	General Information
2	IC50 Value
5	Inhibitors
6	Localization
2	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
14	Organism
1	Pathway
2	pH Optimum
2	pH Range
11	Protein Variants
4	Purification (Commentary)
1	Reaction
14	Reference
1	Renatured (Commentary)
4	Source Tissue
14	Substrates and Products (Substrate)
2	Subunits
19	Synonyms
1	Systematic Name
2	Temperature Stability [°C]

Cloned

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Cloned on EC 4.99.1.8 - heme ligase

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expressed in Escherichia coli BL21(DE3) cells

2 entries

expression in Escherichia coli

2 entries

expression of full length enzyme in Escherichia coli, expression of two truncated enzyme proteins (HDP3 encoded by amino acids 88-205 of the full-length protein, representing the fasciclin domain and HDP2 encoded by amino acids 187 and lacking the fasciclin domain)

Plasmodium falciparum

694830