4.99.1.8: heme ligase
This is an abbreviated version!
For detailed information about heme ligase, go to the full flat file.
![](word_maps/png/4_99_1_8.png)
Word Map on EC 4.99.1.8
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4.99.1.8
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plasmodium
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malaria
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hemozoin
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falciparum
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hemoglobin
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antimalarial
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vacuole
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chloroquine
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detoxify
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medicine
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artemisinins
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reductase-thymidylate
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byproduct
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dihydrofolate
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heme-binding
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polymerization
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yoelii
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analysis
- 4.99.1.8
- plasmodium
- malaria
- hemozoin
- falciparum
- hemoglobin
-
antimalarial
- vacuole
- chloroquine
-
detoxify
- medicine
- artemisinins
-
reductase-thymidylate
-
byproduct
- dihydrofolate
-
heme-binding
- polymerization
- yoelii
- analysis
Reaction
2 ferriprotoporphyrin IX
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Synonyms
alpha-HDP, HDP, heme detoxification protein, heme-detoxification protein
ECTree
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Cloned
Cloned on EC 4.99.1.8 - heme ligase
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expressed in Escherichia coli BL21(DE3) cells
expression in Escherichia coli
expression of full length enzyme in Escherichia coli, expression of two truncated enzyme proteins (HDP3 encoded by amino acids 88-205 of the full-length protein, representing the fasciclin domain and HDP2 encoded by amino acids 187 and lacking the fasciclin domain)
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