4.99.1.3: sirohydrochlorin cobaltochelatase
This is an abbreviated version!
For detailed information about sirohydrochlorin cobaltochelatase, go to the full flat file.
Word Map on EC 4.99.1.3
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4.99.1.3
-
protoporphyrin
-
megaterium
-
typhimurium
-
chlorophyll
-
precorrin-2
-
uroporphyrinogen
-
tetrapyrrole
-
primordial
-
sirohaem
-
dehydrogenation
-
histidine-rich
-
epr
-
atp-independent
-
ferrochelation
- 4.99.1.3
- protoporphyrin
- megaterium
- typhimurium
- chlorophyll
- precorrin-2
- uroporphyrinogen
- tetrapyrrole
-
primordial
-
sirohaem
-
dehydrogenation
-
histidine-rich
- epr
-
atp-independent
-
ferrochelation
Reaction
Synonyms
anaerobic cobalt chelatase, archaeal cobaltochelatase, CbiK, CbiKc, CbiKp, CbiX, CbiX0H, CbiXL, CbiXOH, CbiXS, cobalamin cobalt chelatase, cobalt chelatase, cobaltochelatase, More, sirohydrochlorin cobalt chelatase, sirohydrochlorin cobalt-lyase, sirohydrochlorin cobaltochelatase, sirohydrochlorin-ferrochelatase
ECTree
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Reference on EC 4.99.1.3 - sirohydrochlorin cobaltochelatase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Schubert, H.L.; Raux, E.; Wilson, K.S.; Warren, M.J.
Common chelatase design in the branched tetrapyrrole pathways of heme and anaerobic cobalamin synthesis
Biochemistry
38
10660-10669
1999
Salmonella enterica subsp. enterica serovar Typhimurium
Brindley, A.A.; Raux E.; Leech, H.K.; Schubert, H.L.; Warren, M.J.
A story of chelatase evolution: Identification and characterisation of a small 13-15 kDa 'ancestral' cobaltochelatase (CbiXS) in the Archaea
J. Biol. Chem.
278
22388-22395
2003
Methanosarcina barkeri, Methanobacter thermoautotrophicum, Methanosarcina barkeri Fusaro / DSM 804
Schubert, H.L.; Raux, E.; Matthews, M.A.; Phillips, J.D.; Wilson, K.S.; Hill, C.P.; Warren, M.J.
Structural diversity in metal ion chelation and the structure of uroporphyrinogen III synthase
Biochem. Soc. Trans.
30
595-600
2002
Salmonella enterica subsp. enterica serovar Typhimurium
Leech, H.K.; Raux-Deery, E.; Heathcote, P.; Warren, M.J.
Production of cobalamin and sirohaem in Bacillus megaterium: an investigation into the role of the branchpoint chelatases sirohydrochlorin ferrochelatase (SirB) and sirohydrochlorin cobalt chelatase (CbiX)
Biochem. Soc. Trans.
30
610-613
2002
Priestia megaterium
Raux, E.; Schubert, H.L.; Warren, M.J.
Biosynthesis of cobalamin (vitamin B12): a bacterial conundrum
Cell. Mol. Life Sci.
57
1880-1893
2000
Priestia megaterium, Porphyromonas gingivalis, Clostridium acetobutylicum, Clostridioides difficile, no activity in Bacillus subtilis, Pseudomonas aeruginosa, Cereibacter sphaeroides, Salmonella enterica subsp. enterica serovar Typhimurium, no activity in eukaryota
Raux, E.; Thermes, C.; Heathcote, P.; Rambach, A.; Warren, M.J.
A role for Salmonella typhimurium cbiK in cobalamin (vitamin B12) and siroheme biosynthesis
J. Bacteriol.
179
3202-3212
1997
Salmonella enterica subsp. enterica serovar Typhimurium
Leech, H.K.; Raux, E.; McLean, K.J.; Munro, A.W.; Robinson, N.J.; Borrelly, G.P.; Malten, M.; Jahn, D.; Rigby, S.E.; Heathcote, P.; Warren, M.J.
Characterization of the cobaltochelatase CbiXL: evidence for a 4Fe-4S center housed within an MXCXXC motif
J. Biol. Chem.
278
41900-41907
2003
Synechocystis sp., Priestia megaterium, Priestia megaterium DSM 509
Yin, J.; Xu, L.X.; Cherney, M.M.; Raux-Deery, E.; Bindley, A.A.; Savchenko, A.; Walker, J.R.; Cuff, M.E.; Warren, M.J.; James, M.N.
Crystal structure of the vitamin B12 biosynthetic cobaltochelatase, CbiXS, from Archaeoglobus fulgidus
J. Struct. Funct. Genomics
7
37-50
2006
Archaeoglobus fulgidus (O29537)
Pisarchik, A.; Petri, R.; Schmidt-Dannert, C.
Probing the structural plasticity of an archaeal primordial cobaltochelatase CbiXS
Protein Eng. Des. Sel.
20
257-265
2007
Methanosarcina barkeri (P61816)
Lobo, S.A.; Brindley, A.A.; Romao, C.V.; Leech, H.K.; Warren, M.J.; Saraiva, L.M.
Two distinct roles for two functional cobaltochelatases (CbiK) in Desulfovibrio vulgaris Hildenborough
Biochemistry
47
5851-5857
2008
Desulfovibrio vulgaris (Q72CB8), Desulfovibrio vulgaris (Q72EC8), Desulfovibrio vulgaris Hildenborough (Q72CB8), Desulfovibrio vulgaris Hildenborough (Q72EC8)
Lundqvist, J.; Elmlund, D.; Heldt, D.; Deery, E.; Soederberg, C.A.; Hansson, M.; Warren, M.; Al-Karadaghi, S.
The AAA(+) motor complex of subunits CobS and CobT of cobaltochelatase visualized by single particle electron microscopy
J. Struct. Biol.
167
227-234
2009
Brucella melitensis
Romao, C.V.; Ladakis, D.; Lobo, S.A.; Carrondo, M.A.; Brindley, A.A.; Deery, E.; Matias, P.M.; Pickersgill, R.W.; Saraiva, L.M.; Warren, M.J.
Evolution in a family of chelatases facilitated by the introduction of active site asymmetry and protein oligomerization
Proc. Natl. Acad. Sci. USA
108
97-102
2011
Archaeoglobus fulgidus, Salmonella enterica, Desulfovibrio vulgaris (Q72EC8)
Bali, S.; Rollauer, S.; Roversi, P.; Raux-Deery, E.; Lea, S.M.; Warren, M.J.; Ferguson, S.J.
Identification and characterization of the missing terminal enzyme for siroheme biosynthesis in alpha-proteobacteria
Mol. Microbiol.
92
153-163
2014
Paracoccus denitrificans, Paracoccus pantotrophus
Moore, S.J.; Mayer, M.J.; Biedendieck, R.; Deery, E.; Warren, M.J.
Towards a cell factory for vitamin B12 production in Bacillus megaterium: bypassing of the cobalamin riboswitch control elements
New Biotechnol.
31
553-561
2014
Priestia megaterium, Priestia megaterium DSM 319
Lobo, S.; Videira, M.; Pacheco, I.; Wass, M.; Warren, M.; Teixeira, M.; Matias, P.; Romao, C.; Saraiva, L.
Desulfovibrio vulgaris CbiKP cobaltochelatase evolution of a haem binding protein orchestrated by the incorporation of two histidine residues
Environ. Microbiol.
19
106-118
2017
Desulfovibrio vulgaris (Q72EC8), Desulfovibrio vulgaris DSM 644 (Q72EC8)
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