4.6.1.6: cytidylate cyclase

This is an abbreviated version!
For detailed information about cytidylate cyclase, go to the full flat file.

3',5'-cyclic-CMP synthase, CyaA, cytidyl cyclase, cytidylyl cyclase, Edema factor

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Results	in table
2	Activating Compound
4	AA Sequence
1	CAS Registry Number
21	Inhibitors
3	kcat/KM [mM/s]
13	Ki Value [mM]
6	KM Value [mM]
6	Localization
8	Metals/Ions
9	Natural Substrates/ Products (Substrates)
185	Organism
4	pH Optimum
3	pH Range
1	Reaction
1	Reaction Type
14	Reference
35	Source Tissue
1	Specific Activity [micromol/min/mg]
14	Substrates and Products (Substrate)
7	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Turnover Number [1/s]

pH Range on EC 4.6.1.6 - cytidylate cyclase

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5.5 - 9.5

about 35% of activity maximum at pH 5.5, about 55% of activity maximum at pH 9.5

6 - 8.5

7.4 - 9.4

20% of activity maximum at physiological pH 7.4, maximal activity at pH 9.4, enzyme dispersed from the membrane fraction of brain