Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

4.6.1.13: phosphatidylinositol diacylglycerol-lyase

This is an abbreviated version!
For detailed information about phosphatidylinositol diacylglycerol-lyase, go to the full flat file.

Word Map on EC 4.6.1.13

Reaction

1-phosphatidyl-1D-myo-inositol
=
1D-myo-inositol 1,2-cyclic phosphate
+
1,2-diacyl-sn-glycerol

Synonyms

1-phosphatidyl-D-myo-inositol inositolphosphohydrolase (cyclic-phosphate-forming), 1-phosphatidylinositol phosphodiesterase, EC 3.1.4.10, monophosphatidylinositol phosphodiesterase, More, Phosphatidylinositol diacylglycerol-lyase, phosphatidylinositol phosphodiesterase, phosphatidylinositol phospholipase C, phosphatidylinositol-specific phospholipase C, phosphatidylinositol-specific PLC, phosphatidylinositolphospholipase C, PI-phospholipase C, PI-PLC, PLC, PLC1, PLC2, PLC3, PLC4, PLC5, PLC6

ECTree

     4 Lyases
         4.6 Phosphorus-oxygen lyases
             4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
                4.6.1.13 phosphatidylinositol diacylglycerol-lyase

Inhibitors

Inhibitors on EC 4.6.1.13 - phosphatidylinositol diacylglycerol-lyase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
AOT
-
bis(2-ethylhexyl)sulfosuccinate
Co2+
-
severe inhibition of wild-type PI-PLC
ET-18-OCH3
-
specific inhibitors of PI-PLC, 0.1 mM abolish stimulatory effect of 0.00005 mM heme in the PI-PLC/protein kinase C pathway
KCl
-
above 10 mM
Mn2+
-
2-5 mM, 50% inhibition
myo-inositol
Ni2+
-
severe inhibition of wild-type PI-PLC
p-chloromercuriphenylsulfonic-acid
-
-
U73122
-
specific inhibitors of PI-PLC, 0.05 mM abolish stimulatory effect of heme in the PI-PLC/protein kinase C pathway
vanadate
-
-