4.6.1.1: adenylate cyclase

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For detailed information about adenylate cyclase, go to the full flat file.

Reaction

Synonyms

3',5'-cyclic AMP synthetase, AC, AC 1, AC 2, AC 3, AC 4, AC 5, AC 7, AC 8, AC 9, AC Rv1625c, AC toxin, AC-IV, AC-V, AC-VI, AC1, AC2, AC3, AC4, AC5, AC6, AC7, AC8, AC9, ACA, ACB, ACbeta, ACG, ACI, ACII, ACIII, ACT, ACTP10, ACV, ACVI, ADCY10, Adcy5, adenyl cyclase, adenylate cyclase, adenylate cyclase 1, adenylate cyclase 10, adenylate cyclase 5, adenylate cyclase 6, adenylate cyclase toxin, adenylate cyclase type 10, adenylate cyclase type 5, adenylate cyclase [ATP pyrophosphate-lyase (cyclizing)], Adenylate cyclase, olfactive type, adenylate cyclases I, adenylate cyclases IV, adenylate cyclases VI, adenylyl cyclase, adenylyl cyclase 1, adenylyl cyclase 2, adenylyl cyclase 5, adenylyl cyclase 6, adenylyl cyclase 8, adenylyl cyclase 9, adenylyl cyclase toxin, adenylyl cyclase type 1, Adenylyl cyclase type 10, adenylyl cyclase type 5, adenylyl cyclase type 6, adenylyl cyclase type 8, adenylyl cyclase type V, adenylyl cyclase type VI, adenylyl cyclase VI, adenylyl cyclase VII, adenylyl cyclase, type-V, adenylyl cyclase, type-VI, adenylyl cyclase-5, adenylyl cyclase-beta, adenylyl cyclase-V, adenylyl cyclases 1, adenylyl cyclases 8, adenylylcyclase, Amac3, ATP pyrophosphate-lyase, ATP-diphosphate-lyase cyclizing, ATP-pyrophosphate lyase cyclizing, bacterial photoactivated adenylyl cyclase, BGP_1043, bPAC, Ca(2+)-inhibitable adenylyl cyclase, Ca(2+)/calmodulin activated adenylyl cyclase, Ca(II)- and calmodulin-dependent adenylyl cyclase edema factor, Ca-stimulated type 8 adenylyl cyclase, Ca2+-calmodulin stimulated adenylyl cyclase type 8, Ca2+-dependent adenylyl cyclase, Ca2+/calmodulin-stimulated adenylyl cyclase 1, calcium-sensitive adenylyl cyclase, calcium-stimulated adenylyl cyclase, class I AC, class I adenylate cyclase, class II AC, class III AC, class III adenylate cyclase, class III adenylyl cyclase, class IIIb AC, class IV AC, class IV adenylyl cyclase, class IVadenylyl cyclase, class V AC, class VI AC, Cya, Cya1, CyaA, CyaA toxin, CyaB, cyaB1, CyaB1 adenylyl cyclase, CyaB2, cyaC, CyaG, cyclase, adenylate, Cyr1p, Edema factor, ExoY, G protein-regulated adenylyl cyclase, GRESAG 4.1, GRESAG 4.3, GRESAG4.1, group 1 adenylyl cyclase, IIC2, ion-channel adenylyl cyclase, Ma1120, mAC, MAP0426c, MAP1279c, MAP1318c, MAP1357, MAP2079, MAP2250c, MAP2440, MAP2507c, MAP2672, MAP2695c, MAP3844, MAP4266, membrane adenylyl cyclase, ML1399, MM0123, MM0157, MM0286, MM0666, MM0730, MM0935, MM1414, MM2428, MM2454, MM2550, MM2962, MM3042, MM3043, MM3257, MM3505, MM3522, MM3640, MM3755, MM3757, MM3795, MM4078, MM4079, MM4080, MM4120, MM4173, MM4340, MM4370, MM4438, MM5137, MM5254, MM5257, More, MSMEG0218, MSMEG0536, MSMEG3253, MSMEG3579, MSMEG3786, MSMEG4282, MSMEG4472, MSMEG4909, MSMEG5003, MSMEG6117, Oscil6304_3613, PAC, particulate adenylyl cyclase, PfACalpha, pituitary adenylate cyclase, PleD, Rutabaga protein, Rv0386, Rv0891c, Rv1120c, Rv1264, Rv1318c, Rv1319c, Rv1320c, Rv1358, Rv1359, Rv1625c, Rv1647, Rv1900c, Rv2212, Rv2435c, Rv2488c, Rv3645, Ry1625c, sAC, sACI/II, SACY, Slr1991 adenylyl cyclase, soluble AC, soluble adenylate cyclase, soluble adenylyl cyclase, TczAC, tmAC, transmembrane adenylyl cyclase, transmembrane adenylyl cyclase type 1, transmembrane adenylyl cyclase type 3, transmembrane adenylyl cyclase type 8, type 1 AC, type 1 adenylyl cyclase, type 1 Ca2+/calmodulin-stimulated adenylyl cyclase, type 3 adenylyl cyclase, type 5 adenylyl cyclase, type 6 adenylyl cyclase, type 8 AC, type 8 adenylyl cyclase, type I adenylate cyclase, type II AC, type III adenylyl cyclase, type V AC, type V adenylate cyclase, type V adenylyl cyclase, type VI adenylyl cyclase, type VIII adenylyl cyclase, VC1, xlAC

ECTree

     4 Lyases

         4.6 Phosphorus-oxygen lyases

             4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)

                4.6.1.1 adenylate cyclase

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Results	in table
407	Activating Compound
21518	AA Sequence
87	Application
1	CAS Registry Number
125	Cloned(Commentary)
28	Cofactor
34	Crystallization (Commentary)
13841	Disease/ Diagnostics
5	Expression
20	General Information
3	General Stability
60	IC50 Value
482	Inhibitors
12	kcat/KM [mM/s]
296	Ki Value [mM]
152	KM Value [mM]
218	Localization
235	Metals/Ions
90	Molecular Weight [Da]
192	Natural Substrates/ Products (Substrates)
1352	Organism
4	Pathway
245	PDB ID
60	pH Optimum
15	pH Range
2	pH Stability
9	Posttranslational Modification
260	Protein Variants
83	Purification (Commentary)
1	Reaction
1	Reaction Type
447	Reference
3	Renatured (Commentary)
399	Source Tissue
66	Specific Activity [micromol/min/mg]
12	Storage Stability
417	Substrates and Products (Substrate)
60	Subunits
776	Synonyms
1	Systematic Name
31	Temperature Optimum [°C]
2	Temperature Range [°C]
15	Temperature Stability [°C]
24	Turnover Number [1/s]

Reaction

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Reaction on EC 4.6.1.1 - adenylate cyclase

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REACTION

REACTION DIAGRAM

COMMENTARY

ORGANISM

UNIPROT

LITERATURE

ATP = 3',5'-cyclic AMP + diphosphate

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