4.5.1.3: dichloromethane dehalogenase

This is an abbreviated version!
For detailed information about dichloromethane dehalogenase, go to the full flat file.

Word Map on EC 4.5.1.3

4.5.1.3

s-transferase

methylotrophic

methylophilus

theta

dehalogenation

extorquens

hyphomicrobium

dichloromethanicum

transconjugants

dihalomethanes

glutathione-dependent

methylobacteria

circulans

degradation

Reaction

+ 2 chloride

Synonyms

DCM dehalogenase, DcmA, dcmAa, DehalA, dehalogenase, dichloromethane, dichloromethane chloride-lyase, dichloromethane dehalogenase

ECTree

4 Lyases

4.5 Carbon-halide lyases

4.5.1 Carbon-halide lyases (only sub-subclass identified to date)

4.5.1.3 dichloromethane dehalogenase

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Results	in table
26	Activating Compound
120	AA Sequence
1	Application
1	CAS Registry Number
15	Cloned(Commentary)
12	Cofactor
5	Expression
23	Inhibitors
50	KM Value [mM]
1	Localization
9	Molecular Weight [Da]
43	Natural Substrates/ Products (Substrates)
134	Organism
2	Pathway
5	pH Optimum
1	pH Range
1	pH Stability
1	pI Value
21	Protein Variants
13	Purification (Commentary)
3	Reaction
1	Reaction Type
59	Reference
6	Source Tissue
16	Specific Activity [micromol/min/mg]
1	Storage Stability
94	Substrates and Products (Substrate)
9	Subunits
50	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]
34	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 4.5.1.3 - dichloromethane dehalogenase

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(Z)-1,2-Dichloroethylene

Hyphomicrobium sp.

648754

1,1,2-trichloroethane

weak

1,1-Dichloroethane

1,2-Dichloroethane

1,3-Dichloropropane

1,4-Dichlorobutane

1-Chlorobutane

1-Chloropentane

1-Chloropropane

2,2-Dichloroethyl methyl ether

Hyphomicrobium sp.

648754

2-Chloroethyl methyl ether

chlorobenzene

Dichloroacetic acid

Dichloromethane

an inhibitory effect with increasing dichloromethane concentrations is observed at concentrations higher than 400 mg/l

702492

Methyl dichloroacetate

Hyphomicrobium sp.

648754

Sodium azide

3 entries

[2-(3-chlorophenyl)hydrazinylidene]propanedinitrile

3 entries