4.4.1.4: alliin lyase

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For detailed information about alliin lyase, go to the full flat file.

Word Map on EC 4.4.1.4

4.4.1.4

garlic

allium

allicin

sativum

onion

thiosulfinates

crush

clove

organosulfur

s-alkenyl-l-cysteine

alliaceae

leek

s-allyl-l-cysteine

lachrymatory

medicine

acsos

s-allyl

synthesis

nutrition

drug development

biotechnology

analysis

pharmacology

Reaction

Synonyms

alkylcysteine sulfoxide lyase, alkylsulphenate lyase, ALL1, alliin lyase, alliin-lyase, alliinase, alliinase I, alliinase II, allinase, C-S lyase, C-S-lyase, cys sulfoxide lyase, cysteine sulfoxide lyase, Cysteine sulphoxide lyase, L-(+)-S-alk(en)ylcysteine sulfoxide lyase, L-cysteine sulfoxide lyase, lyase, alliin, More, P-19486 alliinase, S-alkyl(en)yl-L-cysteine lyase, S-alkylcysteine sulfoxide lyase

ECTree

4 Lyases

4.4 Carbon-sulfur lyases

4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)

4.4.1.4 alliin lyase

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Results	in table
1	Activating Compound
57	AA Sequence
19	Application
1	CAS Registry Number
9	Cloned(Commentary)
24	Cofactor
4	Crystallization (Commentary)
1	Expression
3	General Information
6	General Stability
33	Inhibitors
29	kcat/KM [mM/s]
1	Ki Value [mM]
95	KM Value [mM]
4	Localization
34	Molecular Weight [Da]
45	Natural Substrates/ Products (Substrates)
93	Organism
6	Pathway
7	PDB ID
44	pH Optimum
27	pH Range
5	pH Stability
6	pI Value
17	Posttranslational Modification
7	Protein Variants
31	Purification (Commentary)
1	Reaction
2	Reaction Type
93	Reference
42	Source Tissue
23	Specific Activity [micromol/min/mg]
4	Storage Stability
280	Substrates and Products (Substrate)
22	Subunits
51	Synonyms
1	Systematic Name
31	Temperature Optimum [°C]
7	Temperature Range [°C]
10	Temperature Stability [°C]
29	Turnover Number [1/s]

Temperature Optimum

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Temperature Optimum on EC 4.4.1.4 - alliin lyase

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assay at

30 - 35

Allium cepa * Allium altyncolicum

assay at

with the most preferred substrate petiveriin, Petiveria alliacea alliinase shows 80% higher activity at 37°C and 100% higher activity at 52°C than at ambient temperature (25°C). Even at 67°C, alliinase activity is still 19% higher than that observed at room temperature, indicating that the alliinase retains significant functionality over a broad range of temperature and possesses a high overall intrinsic thermal stability