4.4.1.4: alliin lyase
This is an abbreviated version!
For detailed information about alliin lyase, go to the full flat file.
Word Map on EC 4.4.1.4
-
4.4.1.4
-
garlic
-
allium
-
allicin
-
sativum
-
onion
-
thiosulfinates
-
crush
-
clove
-
organosulfur
-
s-alkenyl-l-cysteine
-
alliaceae
-
leek
-
s-allyl-l-cysteine
-
lachrymatory
-
medicine
-
acsos
-
s-allyl
-
synthesis
-
nutrition
-
drug development
-
biotechnology
-
analysis
-
pharmacology
- 4.4.1.4
- garlic
- allium
- allicin
- sativum
- onion
- thiosulfinates
-
crush
- clove
-
organosulfur
-
s-alkenyl-l-cysteine
- alliaceae
- leek
- s-allyl-l-cysteine
-
lachrymatory
- medicine
-
acsos
-
s-allyl
- synthesis
- nutrition
- drug development
- biotechnology
- analysis
- pharmacology
Reaction
Synonyms
alkylcysteine sulfoxide lyase, alkylsulphenate lyase, ALL1, alliin lyase, alliin-lyase, alliinase, alliinase I, alliinase II, allinase, C-S lyase, C-S-lyase, cys sulfoxide lyase, cysteine sulfoxide lyase, Cysteine sulphoxide lyase, L-(+)-S-alk(en)ylcysteine sulfoxide lyase, L-cysteine sulfoxide lyase, lyase, alliin, More, P-19486 alliinase, S-alkyl(en)yl-L-cysteine lyase, S-alkylcysteine sulfoxide lyase
ECTree
4.4.1.4 alliin lyaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 4.4.1.4 - alliin lyase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(+)-(S)-allyl-L-cysteine sulfoxide
2-propenyl 2-propenethiosulfinate + pyruvate + NH3
-
-
i.e. allicin
-
?
(+)-propiin + H2O
propane-1-sulfenic acid + pyruvate + NH3
-
-
-
?
(+-)-propiin + H2O
propane-1-sulfenic acid + pyruvate + NH3
-
-
-
?
(2R)-2-amino-3-(1-phenylethylsulfinyl)propanoic acid
(1-phenylethyl)sulfanol + pyruvate + NH4+
-
-
The sulfenic acid condenses with loss of water to form thiosulfinates. The alpha-aminoacrylic acid formed initially subsequently breaks down into pyruvate and ammonia
-
?
(2R)-2-amino-3-(2-methylbenzylsulfinyl)propanoic acid
(2-methylbenzyl)sulfanol + pyruvate + NH4+
-
-
The sulfenic acid condenses with loss of water to form thiosulfinates. The alpha-aminoacrylic acid formed initially subsequently breaks down into pyruvate and ammonia
-
?
(2R)-2-amino-3-(4-chlorobenzylsulfinyl)propanoic acid
(4-chlorobenzyl)sulfanol + pyruvate + NH4+
-
-
The sulfenic acid condenses with loss of water to form thiosulfinates. The alpha-aminoacrylic acid formed initially subsequently breaks down into pyruvate and ammonia
-
?
(2R)-2-amino-3-(4-methylbenzylsulfinyl)propanoic acid
(4-methylbenzyl)sulfanol + pyruvate + NH4+
-
-
The sulfenic acid condenses with loss of water to form thiosulfinates. The alpha-aminoacrylic acid formed initially subsequently breaks down into pyruvate and ammonia
-
?
(2R)-2-amino-3-(ethylsulfinyl)propanoic acid
(2R)-2-amino-3-(ethylsulfinyl)propanoic acid + pyruvate + NH4+
-
-
The sulfenic acid condenses with loss of water to form thiosulfinates. The alpha-aminoacrylic acid formed initially subsequently breaks down into pyruvate and ammonia
-
?
(2R)-2-amino-3-(phenethylsulfinyl)propanoic acid
phenethylsulfanol + pyruvate + NH4+
-
-
The sulfenic acid condenses with loss of water to form thiosulfinates. The alpha-aminoacrylic acid formed initially subsequently breaks down into pyruvate and ammonia
-
?
(2R)-2-amino-3-(phenylsulfinyl)propanoic acid
phenylsulfanol + pyruvate + NH4+
-
-
The sulfenic acid condenses with loss of water to form thiosulfinates. The alpha-aminoacrylic acid formed initially subsequently breaks down into pyruvate and ammonia
-
?
(R)-S-(2-pyridyl)cysteine N-oxide
2-sulfanylpyridine N-oxide + 2-aminoacrylate
-
-
2-sulfanylpyridine N-oxide can spontaneously rearrange into tautomeric and more stable N-hydroxypyridine-(1H)-thione, which can be transformed to 2-(methyldithio)pyridine N-oxide, 2-[(methylthio)methyldithio]pyridine N-oxide, di(2-pyridyl) disulfide N-oxide, and di(2-pyridyl) disulfide N,N'-dioxide
-
?
2-hydroxyethiin
(2-hydroxyethyl)sulfanol + pyruvate + NH4+
-
-
The sulfenic acid condenses with loss of water to form thiosulfinates. The alpha-aminoacrylic acid formed initially subsequently breaks down into pyruvate and ammonia
-
?
beta-chloro-L-Ala
?
-
95% of the activity with desglutamyl-lentinic acid
-
-
?
isoalliin
? + pyruvate + NH4+
-
-
The sulfenic acid condenses with loss of water to form thiosulfinates. The alpha-aminoacrylic acid formed initially subsequently breaks down into pyruvate and ammonia
-
?
L-(+)-S-(2-pyridyl)-cysteine sulfoxide + H2O
?
-
the amount of this cysteine sulfoxide, related to the fresh weight of bulbs, is between 0.13 and 0.44%
-
-
?
L-Cys sulfinic acid
?
-
0.5% of the activity with desglutamyl-lentinic acid
-
-
?
L-cystine
pyruvate + NH4+ + S2- + L-cysteine
-
cystine lyase activity of the enzyme alliinase
-
-
?
propiin
propylsulfanol + pyruvate + NH4+
-
-
The sulfenic acid condenses with loss of water to form thiosulfinates. The alpha-aminoacrylic acid formed initially subsequently breaks down into pyruvate and ammonia
-
?
S-(+)-allyl-L-cysteine sulfoxide + H2O
allyl 2-propenethiosulphinate
-
-
-
-
?
S-(methylthiomethyl)cysteine 4-oxide
(methylthio)methane-sulfenic acid + 2-aminoacrylate
-
i.e. marasmin
-
-
?
S-benzyl-L-cysteine sulfoxide
phenylmethanesulfenic acid + pyruvate + NH3
-
-
-
-
?
S-butyl-L-cysteine + H2O
butanethiol + NH3 + 2-oxopropanoate
-
-
-
?
S-ethyl-cysteine sulfoxide
diethyldisulfide-S-monoxide + pyruvate + NH4+
-
-
-
-
?
S-ethyl-L-cysteine + H2O
ethanethiol + NH3 + 2-oxopropanoate
-
-
-
?
S-methyl-cysteine sulfoxide
dimethyldisulfide-S-monoxide + pyruvate + NH4+
-
-
-
-
?
S-methyl-L-Cys sulfone
?
-
6% of the activity with desglutamyl-lentinic acid
-
-
?
S-methyl-L-cysteine + H2O
methanethiol + NH3 + 2-oxopropanoate
-
-
-
?
S-propyl-cysteine sulfoxide
dipropyldisulfide-S-monoxide + pyruvate + NH4+
-
-
-
-
?
S-propyl-L-cysteine + H2O
propanethiol + NH3 + 2-oxopropanoate
-
-
-
?
(+)-alliin
allicin + pyruvic acid + NH3
-
isolated from garlic and synthetic substrate (S)-allyl-L-cysteine sulfoxide
i.e. 2-propenyl 2-propenethiosulfinate
-
?
(+)-alliin
allicin + pyruvic acid + NH3
-
i.e. (+)-S-allyl-L-cysteine sulfoxide, low activity, the enzyme is more selectively for (-)-alliin than for (+)-alliin, a naturally occurring substrate for plant alliinase
-
-
?
(+)-S-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
-
-
-
?
(+)-S-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
-
-
-
?
(+)-S-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
-
-
-
?
(+)-S-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
-
-
-
?
(+)-S-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
-
-
-
?
(+)-S-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
-
-
-
?
(+)-S-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
-
-
-
?
(+)-S-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
-
-
-
?
(+)-S-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
-
-
-
?
(+)-S-propyl-L-cysteine sulfoxide
propane-1-sulfenic acid + pyruvate + NH3
-
-
-
-
?
(+)-S-propyl-L-cysteine sulfoxide
propane-1-sulfenic acid + pyruvate + NH3
-
-
-
-
?
(+)-S-propyl-L-cysteine sulfoxide
propane-1-sulfenic acid + pyruvate + NH3
-
-
-
-
?
(+)-S-propyl-L-cysteine sulfoxide
propane-1-sulfenic acid + pyruvate + NH3
-
-
-
-
?
(+)-S-propyl-L-cysteine sulfoxide
propane-1-sulfenic acid + pyruvate + NH3
-
-
-
-
?
(+/-)-(1-methyl)-L-cysteine sulfoxide
methanesulfenic acid + pyruvate + NH3
-
about 15% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(1-methyl)-L-cysteine sulfoxide
methanesulfenic acid + pyruvate + NH3
-
about 10% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(1-methyl)-L-cysteine sulfoxide
methanesulfenic acid + pyruvate + NH3
-
about 30% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(1-methyl)-L-cysteine sulfoxide
methanesulfenic acid + pyruvate + NH3
-
about 15% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(1-methyl)-L-cysteine sulfoxide
methanesulfenic acid + pyruvate + NH3
-
about 35% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(1-methyl)-L-cysteine sulfoxide
methanesulfenic acid + pyruvate + NH3
-
about 10% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(1-methyl)-L-cysteine sulfoxide
methanesulfenic acid + pyruvate + NH3
-
about 35% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(1-methyl)-L-cysteine sulfoxide
methanesulfenic acid + pyruvate + NH3
-
about 15% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(1-methyl)-L-cysteine sulfoxide
methanesulfenic acid + pyruvate + NH3
-
about 45% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(butyl)-L-cysteine sulfoxide
butane-1-sulfenic acid + pyruvate + NH3
-
8% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(butyl)-L-cysteine sulfoxide
butane-1-sulfenic acid + pyruvate + NH3
-
7% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(butyl)-L-cysteine sulfoxide
butane-1-sulfenic acid + pyruvate + NH3
-
about 10% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(butyl)-L-cysteine sulfoxide
butane-1-sulfenic acid + pyruvate + NH3
-
6.5% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(butyl)-L-cysteine sulfoxide
butane-1-sulfenic acid + pyruvate + NH3
-
about 10% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(butyl)-L-cysteine sulfoxide
butane-1-sulfenic acid + pyruvate + NH3
-
6.5% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(butyl)-L-cysteine sulfoxide
butane-1-sulfenic acid + pyruvate + NH3
-
about 15% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(butyl)-L-cysteine sulfoxide
butane-1-sulfenic acid + pyruvate + NH3
-
5% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(butyl)-L-cysteine sulfoxide
butane-1-sulfenic acid + pyruvate + NH3
-
6.5% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(propyl)-L-cysteine sulfoxide
propyl-1-sulfenic acid + pyruvate + NH3
-
4% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(propyl)-L-cysteine sulfoxide
propyl-1-sulfenic acid + pyruvate + NH3
-
about 20% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(propyl)-L-cysteine sulfoxide
propyl-1-sulfenic acid + pyruvate + NH3
-
about 5% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(propyl)-L-cysteine sulfoxide
propyl-1-sulfenic acid + pyruvate + NH3
-
3.5% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(propyl)-L-cysteine sulfoxide
propyl-1-sulfenic acid + pyruvate + NH3
-
about 5% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(propyl)-L-cysteine sulfoxide
propyl-1-sulfenic acid + pyruvate + NH3
-
3.5% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(propyl)-L-cysteine sulfoxide
propyl-1-sulfenic acid + pyruvate + NH3
-
about 10% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(propyl)-L-cysteine sulfoxide
propyl-1-sulfenic acid + pyruvate + NH3
-
7% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-(propyl)-L-cysteine sulfoxide
propyl-1-sulfenic acid + pyruvate + NH3
-
3.5% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(+/-)-alliin
allicin + pyruvic acid + NH3
-
carbon-sulfur (C-S) bond lyase activity of alliinase and catalytic alliinase-specific variable domain of the heavy chain of a heavy-chain antibodies, VHHs, overview
-
-
?
(+/-)-alliin
allicin + pyruvic acid + NH3
-
isolated from garlic and synthetic substrate (S)-allyl-L-cysteine sulfoxide
i.e. 2-propenyl 2-propenethiosulfinate
-
?
(+/-)-alliin
allicin + pyruvic acid + NH3
-
rapid, but thermolabil enzyme reaction
-
-
?
(+/-)-alliin
allicin + pyruvic acid + NH3
-
i.e. (+/-)-S-allyl-L-cysteine sulfoxide, the enzyme is more selectively for (-)-alliin than for (+)-alliin, a naturally occurring substrate for plant alliinase
-
-
?
(+/-)-alliin
allicin + pyruvic acid + NH3
-
i.e. (+/-)-S-allyl-L-cysteine sulfoxide, the enzyme is more selectively for (-)-alliin than for (+)-alliin, a naturally occurring substrate for plant alliinase
-
-
?
(-)-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
about 25% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(-)-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
about 30% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(-)-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
about 25% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(-)-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
about 20% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(-)-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
about 30% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(-)-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
about 3.5% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(-)-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
about 30% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(-)-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
about 15% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(-)-(2-propenyl)-L-cysteine sulfoxide
2-propene-thioic acid + pyruvate + ammonia
-
about 30% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
(-)-alliin
allicin + pyruvic acid + NH3
-
isolated from garlic and synthetic substrate (S)-allyl-L-cysteine sulfoxide
i.e. 2-propenyl 2-propenethiosulfinate
-
?
(-)-alliin
allicin + pyruvic acid + NH3
-
i.e. (-)-S-allyl-L-cysteine sulfoxide, the enzyme is more selectively for (-)-alliin than for (+)-alliin, the enzyme can selectively decompose (-)-alliin, whereas the level of (+)-alliin remains unchanged at least during 30-min incubation
-
-
?
(-)-alliin
allicin + pyruvic acid + NH3
-
i.e. (-)-S-allyl-L-cysteine sulfoxide, best substrate, the enzyme is more selectively for (-)-alliin than for (+)-alliin, a naturally occurring substrate for plant alliinase
-
-
?
(S)-(2-pyrrolyl)cysteine
2-pyrrolesulfenic acid + 2-aminoacrylate
-
-
precursor of the orange-red pigment formed upon wounding. Two molecules of 2-pyrrolesulfenic acid give rise to highly reactive S-(2-pyrrolyl)2-pyrrolethiosulfinate which in turn converts into red 2,2'-epidithio-3,3'-dipyrrole (dipyrrolo[2,3-d:2',3'-e]-1,2-dithiin)
-
?
(S)-(2-pyrrolyl)cysteine
2-pyrrolesulfenic acid + 2-aminoacrylate
-
-
precursor of the orange-red pigment formed upon wounding. Two molecules of 2-pyrrolesulfenic acid give rise to highly reactive S-(2-pyrrolyl)2-pyrrolethiosulfinate which in turn converts into red 2,2'-epidithio-3,3'-dipyrrole (dipyrrolo[2,3-d:2',3'-e]-1,2-dithiin)
-
?
(S)-(2-pyrrolyl)cysteine S-oxide
2-pyrrolesulfenic acid + 2-aminoacrylate
-
-
precursor of the orange-red pigment formed upon wounding. Two molecules of 2-pyrrolesulfenic acid give rise to highly reactive S-(2-pyrrolyl)2-pyrrolethiosulfinate which in turn converts into red 2,2'-epidithio-3,3'-dipyrrole (dipyrrolo[2,3-d:2',3'-e]-1,2-dithiin)
-
?
(S)-(2-pyrrolyl)cysteine S-oxide
2-pyrrolesulfenic acid + 2-aminoacrylate
-
-
precursor of the orange-red pigment formed upon wounding. Two molecules of 2-pyrrolesulfenic acid give rise to highly reactive S-(2-pyrrolyl)2-pyrrolethiosulfinate which in turn converts into red 2,2'-epidithio-3,3'-dipyrrole (dipyrrolo[2,3-d:2',3'-e]-1,2-dithiin)
-
?
(S)-(3-pyrrolyl)cysteine S-oxide
3-pyrrolesulfenic acid + 2-aminoacrylate
-
-
-
-
?
(S)-(3-pyrrolyl)cysteine S-oxide
3-pyrrolesulfenic acid + 2-aminoacrylate
-
-
-
-
?
2 alliin + H2O
allicin + 2 pyruvate + 2 NH3
-
higher affinity of immobilized enzyme toward its substrate
-
-
?
2 S-ethyl-L-Cys sulfoxide + H2O
ethyl ethanethiosulfinate + 2 pyruvate + 2 NH3
-
-
-
-
?
2 S-ethyl-L-Cys sulfoxide + H2O
ethyl ethanethiosulfinate + 2 pyruvate + 2 NH3
-
-
-
-
?
2 S-ethyl-L-Cys sulfoxide + H2O
ethyl ethanethiosulfinate + 2 pyruvate + 2 NH3
-
-
-
-
?
2 S-ethyl-L-Cys sulfoxide + H2O
ethyl ethanethiosulfinate + 2 pyruvate + 2 NH3
-
-
-
-
?
2 S-ethyl-L-Cys sulfoxide + H2O
ethyl ethanethiosulfinate + 2 pyruvate + 2 NH3
-
-
-
-
?
2 S-ethyl-L-Cys sulfoxide + H2O
ethyl ethanethiosulfinate + 2 pyruvate + 2 NH3
-
5% of the activity with desglutamyl-lentinic acid
-
-
?
2 S-ethyl-L-Cys sulfoxide + H2O
ethyl ethanethiosulfinate + 2 pyruvate + 2 NH3
-
-
-
?
alliin
2-propene-thioic acid + pyruvate + NH4+
-
i.e. (2R)-3-(allylsulfinyl)-2-aminopropanoic acid
The sulfenic acid condenses with loss of water to form thiosulfinates. The alpha-aminoacrylic acid formed initially subsequently breaks down into pyruvate and ammonia
-
?
alliin
allylsulfenic acid + pyruvate + NH3
-
-
pure allicin has significantly stronger in vitro inhibitory effect on the growth of six tested fungi (Candida albicans, Cryputococcus neoformans, Trichophyton rubum, Microsporum gypseum, Microsporum canis and Epidermophyton floccosum) than alliin and alliinase
-
?
butiin
butane-1-sulfenic acid + pyruvate + NH3
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
butiin
butane-1-sulfenic acid + pyruvate + NH3
Allium cepa * Allium altyncolicum
-
about 10% of the activity with L-(+)-isoalliin
-
-
?
butiin
butane-1-sulfenic acid + pyruvate + NH3
Allium cepa * Allium chevsuricum
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
butiin
butane-1-sulfenic acid + pyruvate + NH3
Allium cepa * Allium globosum
-
about 15% of the activity with L-(+)-alliin
-
-
?
butiin
butane-1-sulfenic acid + pyruvate + NH3
Allium cepa * Allium oliquum
-
about 15% of the activity with L-(+)-isoalliin
-
-
?
butiin
butane-1-sulfenic acid + pyruvate + NH3
Allium cepa * Allium saxatile
-
about 15% of the activity with L-(+)-alliin
-
-
?
butiin
butane-1-sulfenic acid + pyruvate + NH3
Allium cepa * Allium senescens
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
ethiin
ethanesulfenic acid + pyruvate + NH3
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
ethiin
ethanesulfenic acid + pyruvate + NH3
Allium cepa * Allium altyncolicum
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
ethiin
ethanesulfenic acid + pyruvate + NH3
Allium cepa * Allium chevsuricum
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
ethiin
ethanesulfenic acid + pyruvate + NH3
Allium cepa * Allium globosum
-
about 20% of the activity with L-(+)-alliin
-
-
?
ethiin
ethanesulfenic acid + pyruvate + NH3
Allium cepa * Allium oliquum
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
ethiin
ethanesulfenic acid + pyruvate + NH3
Allium cepa * Allium saxatile
-
about 20% of the activity with L-(+)-alliin
-
-
?
ethiin
ethanesulfenic acid + pyruvate + NH3
Allium cepa * Allium senescens
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
L-(+)-alliin
2-propene-thioic acid + pyruvate + NH4+
-
about 60% of the activity with L-(+)-isoalliin
-
-
?
L-(+)-alliin
2-propene-thioic acid + pyruvate + NH4+
Allium cepa * Allium altyncolicum
-
about 60% of the activity with L-(+)-isoalliin
-
-
?
L-(+)-alliin
2-propene-thioic acid + pyruvate + NH4+
Allium cepa * Allium chevsuricum
-
about 60% of the activity with L-(+)-isoalliin
-
-
?
L-(+)-alliin
2-propene-thioic acid + pyruvate + NH4+
Allium cepa * Allium globosum
-
highest activity
-
-
?
L-(+)-alliin
2-propene-thioic acid + pyruvate + NH4+
Allium cepa * Allium oliquum
-
about 35% of the activity with L-(+)-isoalliin
-
-
?
L-(+)-alliin
2-propene-thioic acid + pyruvate + NH4+
Allium cepa * Allium saxatile
-
highest activity
-
-
?
L-(+)-alliin
2-propene-thioic acid + pyruvate + NH4+
Allium cepa * Allium senescens
-
about 60% of the activity with L-(+)-isoalliin
-
-
?
L-(+)-isoalliin
?
Allium cepa * Allium globosum
-
about 90% of the activity with L-(+)-alliin
-
-
?
L-(-)-alliin
2-propene-thioic acid + pyruvate + NH4+
-
about 30% of the activity with L-(+)-isoalliin
-
-
?
L-(-)-alliin
2-propene-thioic acid + pyruvate + NH4+
Allium cepa * Allium altyncolicum
-
about 20% of the activity with L-(+)-isoalliin
-
-
?
L-(-)-alliin
2-propene-thioic acid + pyruvate + NH4+
Allium cepa * Allium chevsuricum
-
about 25% of the activity with L-(+)-isoalliin
-
-
?
L-(-)-alliin
2-propene-thioic acid + pyruvate + NH4+
Allium cepa * Allium globosum
-
about 40% of the activity with L-(+)-alliin
-
-
?
L-(-)-alliin
2-propene-thioic acid + pyruvate + NH4+
Allium cepa * Allium oliquum
-
about 15% of the activity with L-(+)-isoalliin
-
-
?
L-(-)-alliin
2-propene-thioic acid + pyruvate + NH4+
Allium cepa * Allium saxatile
-
about 55% of the activity with L-(+)-alliin
-
-
?
L-(-)-alliin
2-propene-thioic acid + pyruvate + NH4+
Allium cepa * Allium senescens
-
about 30% of the activity with L-(+)-isoalliin
-
-
?
methiin
methanesulfenic acid + 2-aminoacrylate
-
i.e. (SS,RC)-Smethylcysteine S-oxide
-
-
?
methiin
methanesulfenic acid + 2-aminoacrylate
-
i.e. (SS,RC)-Smethylcysteine S-oxide
-
-
?
methiin + H2O
methanesulfenic acid + pyruvate + NH3
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
methiin + H2O
methanesulfenic acid + pyruvate + NH3
Allium cepa * Allium altyncolicum
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
methiin + H2O
methanesulfenic acid + pyruvate + NH3
Allium cepa * Allium chevsuricum
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
methiin + H2O
methanesulfenic acid + pyruvate + NH3
Allium cepa * Allium globosum
-
about 30% of the activity with L-(+)-alliin
-
-
?
methiin + H2O
methanesulfenic acid + pyruvate + NH3
Allium cepa * Allium oliquum
-
about 10% of the activity with L-(+)-isoalliin
-
-
?
methiin + H2O
methanesulfenic acid + pyruvate + NH3
Allium cepa * Allium saxatile
-
about 35% of the activity with L-(+)-alliin
-
-
?
methiin + H2O
methanesulfenic acid + pyruvate + NH3
Allium cepa * Allium senescens
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
methiin + H2O
methanesulfenic acid + pyruvate + NH3
-
-
The sulfenic acid condenses with loss of water to form thiosulfinates. The alpha-aminoacrylic acid formed initially subsequently breaks down into pyruvate and ammonia
-
?
petiveriin
benzylsulfanol + pyruvate + NH4+
-
-
The sulfenic acid condenses with loss of water to form petivericin. The alpha-aminoacrylic acid formed initially subsequently breaks down into pyruvate and ammonia
-
?
propiin
propane-1-sulfenic acid + pyruvate + NH3
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
propiin
propane-1-sulfenic acid + pyruvate + NH3
Allium cepa * Allium altyncolicum
-
about 10% of the activity with L-(+)-isoalliin
-
-
?
propiin
propane-1-sulfenic acid + pyruvate + NH3
Allium cepa * Allium chevsuricum
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
propiin
propane-1-sulfenic acid + pyruvate + NH3
Allium cepa * Allium globosum
-
about 15% of the activity with L-(+)-alliin
-
-
?
propiin
propane-1-sulfenic acid + pyruvate + NH3
Allium cepa * Allium oliquum
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
propiin
propane-1-sulfenic acid + pyruvate + NH3
Allium cepa * Allium saxatile
-
about 15% of the activity with L-(+)-alliin
-
-
?
propiin
propane-1-sulfenic acid + pyruvate + NH3
Allium cepa * Allium senescens
-
about 5% of the activity with L-(+)-isoalliin
-
-
?
S-(1-butenyl)-L-cysteine sulfoxide
?
-
primary products resulting from the alliinase reaction of homoisoalliin seem to be highly unstable and are rapidly converted
-
-
?
S-(1-butenyl)-L-cysteine sulfoxide
?
-
primary products resulting from the alliinase reaction of homoisoalliin seem to be highly unstable and are rapidly converted
-
-
?
S-allyl-L-cysteine sulfoxide + H2O
2-propene-thioic acid + pyruvate + NH4+ + H+
-
-
-
-
?
S-allyl-L-cysteine sulfoxide + H2O
2-propene-thioic acid + pyruvate + NH4+ + H+
-
-
-
-
?
S-allyl-L-cysteine sulfoxide + H2O
2-propene-thioic acid + pyruvate + NH4+ + H+
-
-
-
-
?
S-allyl-L-cysteine sulfoxide + H2O
2-propene-thioic acid + pyruvate + NH4+ + H+
-
i.e. alliin
-
-
?
S-ethyl-L-Cys sulfoxide + H2O
ethylsulfenic acid + pyruvate + NH3
-
about 30% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
S-ethyl-L-Cys sulfoxide + H2O
ethylsulfenic acid + pyruvate + NH3
-
about 35% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
S-ethyl-L-Cys sulfoxide + H2O
ethylsulfenic acid + pyruvate + NH3
-
about 25% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
S-ethyl-L-Cys sulfoxide + H2O
ethylsulfenic acid + pyruvate + NH3
-
about 50% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
S-ethyl-L-Cys sulfoxide + H2O
ethylsulfenic acid + pyruvate + NH3
-
about 25% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
S-ethyl-L-Cys sulfoxide + H2O
ethylsulfenic acid + pyruvate + NH3
-
about 50% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
S-ethyl-L-Cys sulfoxide + H2O
ethylsulfenic acid + pyruvate + NH3
-
about 25% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
S-ethyl-L-Cys sulfoxide + H2O
ethylsulfenic acid + pyruvate + NH3
-
about 55% of the activity with (+)-S-(2-propenyl)-L-cysteine sulfoxide
-
-
?
S-methyl-L-Cys sulfoxide
?
-
40% of the activity with S-ethyl-L-Cys sulfoxide
-
-
?
S-methyl-L-Cys sulfoxide
?
-
5% of the activity with desglutamyl-lentinic acid
-
-
?
S-propyl-L-Cys sulfoxide
?
-
5% of the activity with desglutamyl-lentinic acid
-
-
?
additional information
?
-
-
3,4-diethyl-1,2,5-trithiane is produced by the action of alliinase in crushed onion
-
-
?
additional information
?
-
-
the enzyme catalyzes the conversion of odorless (+)-S-alk(en)yl-L-cysteine sulfoxides into volatile thiosulfinates
-
-
?
additional information
?
-
-
the enzyme catalyzes the conversion of odorless (+)-S-alk(en)yl-L-cysteine sulfoxides into volatile thiosulfinates
-
-
?
additional information
?
-
-
no activity with (+/-)-(ethyl)-L-cysteine sulfoxide
-
-
?
additional information
?
-
-
the enzyme catalyzes the conversion of odorless (+)-S-alk(en)yl-L-cysteine sulfoxides into volatile thiosulfinates
-
-
?
additional information
?
-
-
the enzyme catalyzes the conversion of odorless (+)-S-alk(en)yl-L-cysteine sulfoxides into volatile thiosulfinates
-
-
?
additional information
?
-
-
the enzyme degrades S-alkyl-L-cysteine sulfoxides, causing the characteristic odor of garlic
-
-
?
additional information
?
-
alliinase catalyzes the synthesis of the chemically and therapeutically active compound allicin, i.e. diallyl thiosulfinate
-
-
?
additional information
?
-
-
alliinase catalyzes the synthesis of the chemically and therapeutically active compound allicin, i.e. diallyl thiosulfinate
-
-
?
additional information
?
-
-
allinase catalyzes the conversion of alliin to allicin, the principal component of potential medicinal value in garlic
-
-
?
additional information
?
-
the disulfide bridge between Cys368 and Cys376, located near the C-terminal, plays an important role in maintaining both the rigidity of the catalytic domain and the substrate-cofactor relative orientation, but alliinase activity does not require free SH groups
-
-
?
additional information
?
-
-
the disulfide bridge between Cys368 and Cys376, located near the C-terminal, plays an important role in maintaining both the rigidity of the catalytic domain and the substrate-cofactor relative orientation, but alliinase activity does not require free SH groups
-
-
?
additional information
?
-
-
cell viability of B16 F10 (B16) cells treated with catalytic alliinase-specific variable domain of the heavy chain of a heavy-chain antibodies, VHHs, is reduced
-
-
?
additional information
?
-
-
substrate is gained from different garlic sources or synthetically
-
-
?
additional information
?
-
-
the enzyme catalyzes the conversion of odorless (+)-S-alk(en)yl-L-cysteine sulfoxides into volatile thiosulfinates
-
-
?
additional information
?
-
-
the enzyme catalyzes the conversion of odorless (+)-S-alk(en)yl-L-cysteine sulfoxides into volatile thiosulfinates
-
-
?
additional information
?
-
-
the enzyme catalyzes the conversion of odorless (+)-S-alk(en)yl-L-cysteine sulfoxides into volatile thiosulfinates
-
-
?
additional information
?
-
-
the enzyme catalyzes the conversion of odorless (+)-S-alk(en)yl-L-cysteine sulfoxides into volatile thiosulfinates
-
-
?
additional information
?
-
-
the enzyme is responsible for the degradative conversion of S-alk(en)yl-L-Cys sulfoxide to volatile odorous sulfur-containing metabolites
-
-
?
additional information
?
-
-
the enzyme catalyzes the conversion of odorless (+)-S-alk(en)yl-L-cysteine sulfoxides into volatile thiosulfinates
-
-
?
additional information
?
-
enzyme additionally catalyzes the beta-elimination reaction of (+-)-S-alk(en)yl-L-cysteine sulfoxides to yield thiosulfinate, reaction of EC 4.4.1.4. It can decompose both diastereomers equally
-
-
?
additional information
?
-
-
enzyme additionally catalyzes the beta-elimination reaction of (+-)-S-alk(en)yl-L-cysteine sulfoxides to yield thiosulfinate, reaction of EC 4.4.1.4. It can decompose both diastereomers equally
-
-
?
additional information
?
-
-
substrate specificity, overview. The C-S lyase activity is also detected with this bacterial enzyme when S-alkyl-L-cysteine is used as a substrate, though such a lyase activity is absolutely absent in alliinase of plant origin, cf. EC 4.4.1.6
-
-
?
additional information
?
-
-
substrate specificity, overview. The C-S lyase activity is also detected with this bacterial enzyme when S-alkyl-L-cysteine is used as a substrate, though such a lyase activity is absolutely absent in alliinase of plant origin, cf. EC 4.4.1.6
-
-
?
additional information
?
-
-
functions in the sequence of the lenthionine formation from lentinic acid
-
-
?
