4.4.1.4: alliin lyase

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For detailed information about alliin lyase, go to the full flat file.

Word Map on EC 4.4.1.4

4.4.1.4

garlic

allium

allicin

sativum

onion

thiosulfinates

crush

clove

organosulfur

s-alkenyl-l-cysteine

alliaceae

leek

s-allyl-l-cysteine

lachrymatory

medicine

acsos

s-allyl

synthesis

nutrition

drug development

biotechnology

analysis

pharmacology

Reaction

Synonyms

alkylcysteine sulfoxide lyase, alkylsulphenate lyase, ALL1, alliin lyase, alliin-lyase, alliinase, alliinase I, alliinase II, allinase, C-S lyase, C-S-lyase, cys sulfoxide lyase, cysteine sulfoxide lyase, Cysteine sulphoxide lyase, L-(+)-S-alk(en)ylcysteine sulfoxide lyase, L-cysteine sulfoxide lyase, lyase, alliin, More, P-19486 alliinase, S-alkyl(en)yl-L-cysteine lyase, S-alkylcysteine sulfoxide lyase

ECTree

4 Lyases

4.4 Carbon-sulfur lyases

4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)

4.4.1.4 alliin lyase

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Results	in table
1	Activating Compound
57	AA Sequence
19	Application
1	CAS Registry Number
9	Cloned(Commentary)
24	Cofactor
4	Crystallization (Commentary)
1	Expression
3	General Information
6	General Stability
33	Inhibitors
29	kcat/KM [mM/s]
1	Ki Value [mM]
95	KM Value [mM]
4	Localization
34	Molecular Weight [Da]
45	Natural Substrates/ Products (Substrates)
93	Organism
6	Pathway
7	PDB ID
44	pH Optimum
27	pH Range
5	pH Stability
6	pI Value
17	Posttranslational Modification
7	Protein Variants
31	Purification (Commentary)
1	Reaction
2	Reaction Type
93	Reference
42	Source Tissue
23	Specific Activity [micromol/min/mg]
4	Storage Stability
280	Substrates and Products (Substrate)
22	Subunits
51	Synonyms
1	Systematic Name
31	Temperature Optimum [°C]
7	Temperature Range [°C]
10	Temperature Stability [°C]
29	Turnover Number [1/s]

General Information

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General Information on EC 4.4.1.4 - alliin lyase

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metabolism

Petiveria alliacea

lachrymatory factor synthase and alliinase function in tandem, with the alliinase furnishing the sulfenic acid substrate on which the lachrymatory factor synthase acts. The lachrymatory factor synthase modulates the formation of biologically active thiosulfinates that are downstream of the alliinase in a manner dependent upon the relative concentrations of the lachrymatory factor synthase and the alliinase. These observations suggest that manipulation of lachrymatory factor synthase-to-alliinase ratios in plants displaying this system may provide a means by which to rationally modify organosulfur small molecule profiles to obtain desired flavor and/or odor signatures, or increase the presence of desirable biologically active small molecules

706312

physiological function

2 entries