4.4.1.34: isoprene-epoxide-glutathione S-transferase
This is an abbreviated version!
For detailed information about isoprene-epoxide-glutathione S-transferase, go to the full flat file.
Reaction
Synonyms
IsoI, isol
ECTree
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Systematic Name
Systematic Name on EC 4.4.1.34 - isoprene-epoxide-glutathione S-transferase
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2-(glutathion-S-yl)-2-methylbut-3-en-1-ol lyase [(3R)-3,4-epoxy-3-methylbut-1-ene forming]
The enzyme, characterized from the bacterium Rhodococcus sp. AD45, is involved in isoprene degradation. The enzyme can catalyse the glutathione-dependent ring opening of various epoxides, but the highest activity is with (3R)-3,4-epoxy-3-methylbut-1-ene, which is derived from isoprene by EC 1.14.13.69, alkene monooxygenase.