4.4.1.21: S-ribosylhomocysteine lyase

This is an abbreviated version!
For detailed information about S-ribosylhomocysteine lyase, go to the full flat file.

Word Map on EC 4.4.1.21

4.4.1.21

quorum

quorum-sensing

interspecies

harveyi

thioether

4,5-dihydroxy-2,3-pentanedione

nucleosidase

luxs-dependent

furanone

medicine

analysis

Reaction

Synonyms

AI-2 synthase, autoinducer-2 synthase, BsLuxS, EC 3.13.1.2, EC 3.2.1.148, EC 3.3.1.3, EcLuxS, lsrR, Lux S, LuxS, LuxS protein, S-ribosyl homocysteinase, S-ribosylhomocysteinase, S-ribosylhomocysteine lyase, S-ribosylhomocysteinelyase, VhLuxS

ECTree

4 Lyases

4.4 Carbon-sulfur lyases

4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)

4.4.1.21 S-ribosylhomocysteine lyase

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Results	in table
2	Activating Compound
10500	AA Sequence
2	Application
1	CAS Registry Number
21	Cloned(Commentary)
7	Crystallization (Commentary)
1	Expression
34	General Information
2	General Stability
35	Inhibitors
5	kcat/KM [mM/s]
32	Ki Value [mM]
32	KM Value [mM]
35	Metals/Ions
1	Molecular Weight [Da]
33	Natural Substrates/ Products (Substrates)
183	Organism
1	Oxidation Stability
8	Pathway
11	PDB ID
1	pH Optimum
2	pI Value
46	Protein Variants
9	Purification (Commentary)
3	Reaction
13	Reaction Type
160	Reference
2	Source Tissue
1	Storage Stability
135	Substrates and Products (Substrate)
7	Subunits
188	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Stability [°C]
23	Turnover Number [1/s]

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Cloned on EC 4.4.1.21 - S-ribosylhomocysteine lyase

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Bacillus subtilis

654703

as lsrR knockout by chromosomal gene replacement

Escherichia coli

Q8X902

680464

expressed in Escherichia coli DH5alpha cells

4 entries

expression in Escherichia coli

3 entries

expression in Escherichia coli BL21

Bacillus subtilis

O34667

657179

gene luxS, DNA and amino acid sequence determination and analysis, sequence comparisons

Phocaeicola vulgatus

A6KYS6

729946

gene luxS, DNA and amino acid sequence determination and analysis, sequence comparisons, the functional luxS orthologue can complement autoinducer AI-2 production in Escherichia coli strain BL21(DE3)

Bacteroides fragilis

729946

gene luxS, sequence comparisons, expression and transcriptome analysis of wild-type and enzyme knockout mutant strains

Streptococcus suis

A4VTE8

730192

gene luxS, soluble expression of GST-tagged enzyme in Escherichia coli strain BL21(DE3)

Streptococcus mutans

728897

LuxS variants are overexpressed in Escherichia coli in their Fe2+, Zn2+- and Co2+-substituted forms

2 entries

mutant LuxS variants are overexpressed in Escherichia coli in both Zn2+- and Co2+-substituted forms

3 entries

mutant LuxS variants are overexpressed in Escherichia coli in their Fe2+, Zn2+- and Co2+-substituted forms

Vibrio harveyi

Q9Z5X1

678153

overexpression as glutathione-S-transferase fusion in Escherichia coli

Vibrio harveyi

656826