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4.4.1.2: homocysteine desulfhydrase

This is an abbreviated version!
For detailed information about homocysteine desulfhydrase, go to the full flat file.

Reaction

2-aminobut-2-enoate
=
2-iminobutanoate

Synonyms

desulfhydrase, homocysteine, homocysteine desulfurase, Hyc gamma-lyase

ECTree

     4 Lyases
         4.4 Carbon-sulfur lyases
             4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)
                4.4.1.2 homocysteine desulfhydrase

Substrates Products

Substrates Products on EC 4.4.1.2 - homocysteine desulfhydrase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
glycine + H2O
?
show the reaction diagram
L-alanine + H2O
?
show the reaction diagram
L-asparagine + H2O
?
show the reaction diagram
L-cysteine + H2O
2-oxopropanoate + NH3 + ?
show the reaction diagram
-
43.3% of the oxo-acid release activity compared to L-homocysteine as substrate
-
-
?
L-cystine + H2O
?
show the reaction diagram
L-homocysteine + H2O
H2S + NH3 + 2-oxobutanoate
show the reaction diagram
L-homocysteine + H2O
hydrogen sulfide + NH3 + 2-oxobutanoate
show the reaction diagram
L-lysine + H2O
?
show the reaction diagram
-
27.1% of the oxo-acid release activity compared to L-homocysteine as substrate
-
-
?
L-methionine + H2O
2-oxobutanoate + NH3 + ?
show the reaction diagram
-
90% of the oxo-acid release compared to L-homocysteine as substrate
-
-
?